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Cancer of Unknown Primary Symptoms

Symptoms of cancer of unknown primary (CUP) vary from person to person and depend on where the cancer has spread. They may include:

  • Swollen lymph nodes that are firm and not painful
  • Mass in the abdomen that can be felt from the outside or causes a feeling of fullness after a small meal
  • Shortness of breath
  • Pain in the chest or abdomen
  • Pain in the bones
  • Skin tumors
  • Fatigue or weakness
  • Lack of appetite or unexplained weight loss

These symptoms do not always mean you have CUP. However, it is important to discuss any symptoms with your doctor, since they may signal other health problems.

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Knowledge Center

Find the latest news and information about cancer of unknown primary in our Knowledge Center, including blog posts, articles, videos, news releases and more.