
Protein Array and Analysis Core
Mark Bedford, Ph.D. Director
Shawn Bratton, Ph.D. Co-Director
- Research Resources
- Core Facilities and Services
- Protein Array and Analysis Core
The Protein Array and Analysis Core (PAAC) at the University of Texas MD Anderson Cancer Center provides investigators access to innovative and cutting-edge cancer research tools for the discovery and characterization of novel protein-protein interactions. This is accomplished using a state-of-the-art protein microarrayer and additional equipment that will provide biophysical analysis of protein-protein interactions. The PAAC is supported by a grant from Cancer Prevention and Research Institute of Texas (CPRIT). Please acknowledge use of this core in your publications (CPRIT RP 180804).
Apart from identifying novel protein-protein interactions that are mediated between protein peptides and protein domains we will provide the know-how and instrumentation to determine the strength of these protein-protein interactions. Discovering new nodes of interaction in signal transduction pathways is important because these protein networks are often deregulated in cancers. Importantly, these pathways can be targeted with drugs that inhibit the enzyme that deposits the posttranslational modifications that facilitate many of these interactions. Also, protein-protein interactions can be directly targeted with small molecules using these arrays. These findings will lay the groundwork, and identify the targets, for future cancer drug discovery projects.
Submitting Samples
For shipping via FedEx or UPS, address to:
Mark Bedford, Ph.D.
The University of Texas MD Anderson Cancer Center
Department of Epigenetics and Molecular Carcinogenesis
1901 East Road
Houston, TX 77054-1901
Contact Us
Directors
Mark Bedford, Ph.D.
Director, Protein Array and Analysis Core
Professor, Epigenetics and Molecular Carcinogenesis
512-237-9539
mtbedford@mdanderson.org
Shawn B. Bratton, Ph.D.
Co-Director, Protein Array and Analysis Core
Associate Professor, Epigenetics and Molecular Carcinogenesis
512-237-9461
sbbratton@mdanderson.org
Mailing Address:
University of Texas MD Anderson Cancer Center
Department of Epigenetics and Molecular Carcinogenesis
Unit 1951
P.O. Box 301429
Houston, TX 77230-1429
Shipping Address:
University of Texas MD Anderson Cancer Center
Department of Epigenetics and Molecular Carcinogenesis
1901 East Road
Houston, TX 77054-1901