Nuclear Magnetic Resonance Facility
Kumaralal K. Kaluarachchi, Ph.D.
Core Manager
- Research Resources
- Core Facilities and Services
- Nuclear Magnetic Resonance Facility
Overview
The Nuclear Magnetic Resonance (NMR) Facility houses three state-of-the-art spectrometers for use in the determination of the structure of small molecules and biological macromolecules, reaction kinetics, macromolecule dynamics, metabolism, etc. Samples are analyzed either by individual users or by Kumar Kaluarachchi, Ph.D., the facility manager. Go to the About page to learn more about the core.
Getting Started
Contact Kumar Kaluarachchi, Ph.D. at 713-792-3779 to schedule training on the instruments or to request the analysis of your samples.
ID badges of new users are activated to access the NMR room after they receive training. During regular hours, the 600 MHz instrument can be used for 30 minutes and the 500 MHz and 300 MHz instruments can be used for two hours. Longer experiments should be set up for overnights or weekends.
Instrument time should be scheduled through iLab.
Impact
Nuclear Magnetic Resonance plays a major role in organic synthesis, drug discovery, drug- macro molecular interaction and metabolomics which are greatly important in cancer research. It can also be used to determine conformational and configurational alterations. With the cryo-probe, it is possible to increase the sensitivity of the NMR spectra. HRMAS probes can be used to obtain spectra of swellable or gel like samples which can provide spectra similar to those obtained with solution-state NMR. These capabilities provide invaluable services to the cancer researchers at MD Anderson Cancer Center.
Acknowledgment
Please use the following text when acknowledging the core: "This study was supported by the Nuclear Magnetic Resonance Facility, University of Texas MD Anderson Cancer Center."
Go to the Acknowledgment page to see guidelines on whether the efforts of core personnel merit authorship.
Contact
Facility Location
1901 East Road, Houston, TX, 77054
Room 4SCR1.1335
Core Manager
Kumar Kaluarachchi, Ph.D.
Phone: 713-792-3779
Email: kkaluarachchi@mdanderson.org