Publications
Ferrara F, Staquicini DI, Driessen WH, D'Angelo S, Dobroff AS, Barry M, Lomo LC, Staquicini FI, Cardó-Vila M, Soghomonyan S, Alauddin MM, Flores LG, Arap MA, Lauer RC, Mathew P, Efstathiou E, Aparicio AM, Troncoso P, Navone NM, Logothetis CJ, Marchiò S, Gelovani JG, Sidman RL, Pasqualini R, Arap W. Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer. Proc Natl Acad Sci USA. e-Pub 10/2016. PMID: 27791181.
Najjar AM, Manuri PR, Olivares S, Flores L 2nd, Mi T, Huls H, Shpall EJ, Champlin RE, Turkman N, Paolillo V, Roszik J, Rabinovich B, Lee DA, Alauddin M, Gelovani J, Cooper LJ. Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography. Mol Imaging Biol 18(6). e-Pub 5/2016. PMCID: PMC5096958 [Available on 2016-12-01].
Perera S, Piwnica-Worms D, Alauddin MM. Synthesis of a [18F]-labeled ceritinib analogue for positron emission tomography of anaplastic lymphoma kinase, a receptor tyrosine kinase, in lung cancer. Journal of Labelled Compound and Radiopharmaceuticals 59(3):103-08, 3/2016. PMCID: PMC4863448.
Varkaris A, Corn PG, Parikh NU, Efstathiou E, Song JH, Lee YC, Aparicio AM, Hoang A, Gaur S, Thorpe L, Maity SN, Bar-Eli M, Czerniak BA, Shao Y, Alauddin M, Lin SH, Logothetis CJ, Gallick GE. Integrating murine and clinical trials with cabozantinib to understand roles of MET and VEGFR-2 as targets for growth inhibition of prostate cancer. Clin Cancer Res 22(1). e-Pub 8/2015. PMCID: PMC4703437 [Available on 2017-01-01].
Alauddin MM, De Palatis L. Current and Future Trends in Early Detection of Pancreatic Cancer: Molecular Targets and PET Probes. Curr Med Chem 22(29):3370-89, 2015. e-Pub 9/2015. PMID: 26295468.
Bonomi R, Mukhopadhyay U, Shavrin A, Yeh HH, Majhi A, Dewage SW, Najjar A, Lu X, Cisneros GA, Tong WP, Alauddin MM, Liu RS, Mangner TJ, Turkman N, Gelovani JG. Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain. PLoS One 10(8):e0133512, 10(8): e0133512. doi:10.1371/journal.pone.0133512., 2015. e-Pub 8/2015. PMCID: PMC4526562.
Bhatnagar P, Alauddin M, Bankson JA, Kirui D, Seifi P, Huls H, Lee DA, Babakhani A, Ferrari M, Li KC, Cooper LJ. Tumor Lysing Genetically Engineered T Cells Loaded with Multi-Modal Imaging Agents. Sci Rep 4:4502, 2014. e-Pub 3/2014. PMCID: PMC3968458.
Chan PC, Wu CY, Chang WT, Lin CY, Tseng YL, Liu RS, Alauddin MM, Lin WJ, Wang HE.. Monitoring tumor response with [(18)F]FMAU in a sarcoma-bearing mouse model after liposomal vinorelbine treatment. Nucl. Med Biol 40(8). e-Pub 8/2013. PMID: 23969084.
Turkman N, Gelovani JG, Alauddin MM. An improved synthesis of 1′-[18F]fluoroethyl-β-D-lactose ([18F]-FEL) for PET imaging of pancreatic cancer. J Labelled Comp Radiopharm 56(7):351-355, 6/2013. e-Pub 3/2013. PMCID: PMC4171848.
Flores LG, Yeh HH, Soghomonyan S, Young D, Bankson J, Hu Q, Alauddin M, Huff V, Gelovani JG. Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using 18F-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth. Mol Imaging Biol 15(2):175-85, 4/2013. e-Pub 8/2012. PMCID: PMC3591528.
Yeh HH, Tian M, Hinz R, Young D, Shavrin A, Mukhapadhyay U, Flores LG, Balatoni J, Soghomonyan S, Jeong HJ, Pal A, Uthamanthil R, Jackson JN, Nishii R, Mizuma H, Onoe H, Kagawa S, Higashi T, Fukumitsu N, Alauddin M, Tong W, Herholz K, Gelovani JG. Imaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with 18F-FAHA. Neuroimage 1(64):630-9, 1/2013. e-Pub 9/2012. PMCID: PMC3540799.
Turkman N, Paolillo V, Gelovani JG, Alauddin MM. An investigation on stereospecific fluorination at the 2′-arabino-position of a pyrimidine nucleoside: radiosynthesis of 2′-deoxy-2′-[18F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil. Tetrahedron 68(50):10326-10332, 12/2012. PMCID: PMC3539786.
Turkman N, Shavrin A, Paolillo V, Yeh HH, Flores L, Soghomonian S, Rabinovich B, Volgin A, Gelovani J, Alauddin MM. Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptor. Nucl. Med Biol 39(4):593-600, 5/2012. e-Pub 1/2012. PMCID: PMC3324652.
Nishii R, Tong W, Wendt R, Soghomonyan S, Mukhopadhyay U, Balatoni J, Mawlawi O, Bidaut L, Tinkey P, Borne A, Alauddin M, Gonzalez-Lepera C, Yang B, Gelovani JG. Pharmacokinetics, Metabolism, Biodistribution, Radiation Dosimetry, and Toxicology of 18F-Fluoroacetate (18F-FACE) in Non-Human Primates. Mol Imaging Biol 14(2):213-24, 4/2012. e-Pub 3/2011. PMCID: PMC3902791.
Paolillo V, Yeh HH, Mukhopadhyay U, Gelovani JG, Alauddin MM. Improved detection and measurement of low levels of [18F]fluoride metabolized from [18F]-labeled pyrimidine nucleoside analogues in biological samples. Nucl. Med Biol 38(8):1129-1134, 11/2011. e-Pub 7/2011. PMCID: PMC3230730.
Chan PC, Wu CY, Chang WY, Chang WT, Alauddin MM, Liu RS, Lin WJ, Chen FD, Chen CL, Wang HE.. Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging. Nucl. Med. Biol. 38(7):987-95, 10/2011. PMID: 21982570.
Pal A, Balatoni JA, Mukhopadhyay U, Ogawa K, Gonzalez-Lepera C, Shavrin A, Volgin A, Tong W, Alauddin MM, Gelovani JG. Radiosynthesis and Initial In Vitro Evaluation of [(18)F]F-PEG (6)-IPQA-A Novel PET Radiotracer for Imaging EGFR Expression-Activity in Lung Carcinomas. Mol Imaging Biol 13(5):853-61, 10/2011. e-Pub 9/2010. PMID: 20859697.
Turkman N, Shavrin A, Ivanov RA, Rabinovich B, Volgin A, Gelovani JG, Alauddin MM. Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives. Bioorg Med Chem 19(18):5698-707, 9/2011. e-Pub 8/2011. PMCID: PMC3174488.
Perin E, Tian M, Silva G, Marini FC, Zheng Y, Baimbridge F, Quan X, Young D, Paolillo V, Mukhopadhyay U, Gonzales-Lepera C, Borne A, Uthamanthil R, Brammer D, Jackson J, Decker W, Najjar, A, Thomas M, Soghomonyan S, Jeong H, Rios J, Vela D, Steiner D, Robinson S, Mawlawi O, Pan T, Stafford J, Kundra V, Li C, Alauddin MM, Shpall E, Gelovani JG. Imaging the Long-Term Fate of Mesenchymal Stem Cells after Intramyocardial Transplantation in a Porcine Model of Myocardial Infarction. PLoS ONE 6(9), 9/2011. PMCID: PMC3164664.
Turkman N, Pal A, Tong W, Gelovani JG, Alauddin MM. Radiosynthesis of 1′-[18F]fluoroethyl-β-D-lactose ([18F]-FEL) for early detection of pancreatic carcinomas with PET. J. Labelled. Comp. Radiopharm. 54:233-238, 7/2011.