Alauddin Laboratory
Mian M. Alauddin, Ph.D.
Principal Investigator
Cancer Systems Imaging
Associate Professor
Areas of Research
- Imaging
Research efforts in the laboratory of Mian Alauddin, Ph.D. focus on the development of PET probes for non-invasive in vivo molecular imaging of early stage cancer and therapy evaluation as well as radiolabeling of monoclonal antibodies and peptides for cancer diagnosis and therapy.
His area of specialization includes the synthesis and radiosynthesis of small organic molecules, which are substrates for specific target such as enzymes or receptors over expressing in cancer cells. In addition, biological evaluation of the newly developed PET probes in vitro in cell culture and in vivo in small and large animals for preclinical evaluation are also part of the research interest.
Development of radiolabeled monoclonal antibodies and peptides using radiometal for cancer diagnosis and therapy, and monitoring therapy outcome are of special interest.
Research Projects
New generation of radiotracers for PET imaging of molecular signatures of tumors
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Victor Krasnykh
Duration: 8/7/2014 - 7/31/2017
In situ redirection of T cell specificity and imaging of targeted CAR expression
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Eshhar
Duration: 9/1/2013 - 8/31/2017
The goal of this project is to image targeted chimeric antibody receptor expression in T cell using positron emission tomography and 18F-FEAU.
Grants
Current
Co-Investigator, 0.6 months, In situ redirection of T cell specificity and imaging of targeted
CAR expression, 1R01EB017206-01, NIH/NCI, PI - Eshhar, 9/1/2013−8/31/2017
Co-Investigator, 0.24 months, New generation of radiotracers for PET imaging of molecular signatures of tumors, 1R21CA185714-01, NIH/NCI, PI - Victor Krasnykh, 8/7/2014−7/31/2017
Related Links
Contact
The University of Texas MD Anderson Cancer Center
Cancer Systems Imaging
1881 East Road
Unit Number: 1907
Houston, TX 77054-1901
Room Number: 3SCR4.3626
Phone: 713-563-4872
Fax: 713-794-5456
Email: alauddin@mdanderson.org