Phase II Study of Hyper-CVAD plus Nelarabine in Previously Untreated T-ALL and Lymphoblastic Lymphoma
Adriamycin, Asparaginase, Compound 506, Cyclophosphamide, Cytarabine, Decadron, Mercaptopurine, Methotrexate, Prednisone, Vincristine
The goal of this clinical research study is to learn the effectiveness of intensive chemotherapy given in combination with nelarabine (followed by maintenance therapy) in the treatment of patients with T cel ALL and T cell lymphoblastic lymphoma. The safety of this treatment will also be studied.
Disease Group: Leukemia
Treatment Agent: Adriamycin, Asparaginase, Compound 506, Cyclophosphamide, Cytarabine, Decadron, Mercaptopurine, Methotrexate, Prednisone, Vincristine
Treatment Location: Only at MD Anderson
Estimatated Length of Stay in Houston: Minimum of 21 days during the first course, and at least 5 days during the ;second course.
Return Visit: Every one to 3 months as long as receiving active therapy. Thereafter every 3 to 6 months as long as on study.
Home Care: All chemotherapy (except course 1 and drug administration phase of course 2) ;and follow up may be provided for at home
IRB Review and Approval Date: 08/22/2006
Recruitment Status: Open
Projected Accrual: N/A
Information and next steps
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