Ruxolitinib shrinks swollen spleens, eases debilitating
symptoms of incurable malignancy
MD Anderson News Release 02/29/12
A drug that relieves the severe symptoms of a life-threatening bone
marrow cancer called myelofibrosis also improves the survival of
patients with the disease, according to a phase III clinical trial
published in the March 1 edition of New England Journal of Medicine.
Study shows resilient cells lengthen telomeres by other
means; identifies targets to defeat effect
MD Anderson News Release 02/20/12
Inhibiting telomerase, an enzyme that rescues malignant cells from
destruction by extending the protective caps on the ends of
chromosomes, kills tumor cells but also triggers resistance pathways
that allow cancer to survive and spread, scientists report in the Feb.
17 issue of Cell...