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Symptom Research Hosts Panel on Developing Strategies for Reducing Cancer Treatment-Related Toxicities and Symptoms

There is little recognition of the large numbers of patients and survivors who are affected by severe symptoms, and insufficient industry interest in developing and testing agents that can address these problems. In contrast to the rapid progress in curative therapies, little systematic research is being conducted on the mechanisms that cause treatment-related symptoms, developing and exploiting preclinical animal models of these symptoms, phase 1-2 studies of symptom prevention and management, or developing an evidence base for new and existing symptom-focused interventions through the clinical trials groups.

In March 2011, the Department of Symptom Research and the Friends of Cancer Research convened stakeholders in cancer research, industry, regulation, and advocacy to identify the challenges that have prevented progress in reducing treatment-related symptom burden, to develop a list of strategic steps to meet these challenges, and to develop a white paper to identify how to implement these steps.

Cancer Symptom Science: Measurement, Mechanisms, and Management

Edited by Charles S. Cleeland, Michael J. Fisch, and Adrian J. Dunn

Cancer Symptom Science - the bookCancer Symptom Science is the first interdisciplinary compilation of research on the mechanisms underlying the expression of cancer-related symptoms. It presents innovations in clinical, animal and in vitro research, research methods in brain imaging, and statistical-descriptive approaches to understanding the mechanistic basis of symptom expression. It also provides perspectives from patients, government and industry. By collecting and synthesizing the developing threads of new approaches to understanding cancer-related symptoms, the book promotes a pioneering framework for merging behavioral and biological disciplines to clarify mechanisms of symptom evolution, incorporating new technologies, testing novel agents for symptom control, and improving patient functioning and quality of life both during and after cancer treatment.

The editorial team includes MD Anderson faculty Charles Cleeland, PhD, chair of the Department of Symptom Research and Michael Fisch, MD, MPH, chair of the Department of General Oncology; and Adrian Dunn, PhD, of The University of Hawaii at Manoa. The book is targeted toward surgical, clinical and medical oncologists, nurses, academic researchers, fellows and nursing students, and pharmaceutical companies developing new agents to control symptom expression.

Cancer Symptom Science is available from Cambridge University Press and at bookstores online.

MD Anderson Publications Focus on Symptom Research

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© 2014 The University of Texas MD Anderson Cancer Center