Bioinformatics and Computational Biology
John N. Weinstein, M.D., Ph.D., Chair
The focus of research in the Department of Bioinformatics and Computational Biology is microarray data analysis, biomarker identification, drug target discovery, functional genomics and proteomics, coding sequence analysis, cross-validation analysis, forensic applications of genetics and the analysis of genetic trait inheritance. Other areas of specialization include analyzing the effects of radiotherapy, cell population dynamics, molecular confirmation studies, modeling biological processes, computer-assisted diagnosis, computer-assisted image interpretation, statistical graphics and the analysis of cell cycle regulatory proteins.
The Bioinformatics Group within the department serves as a component of the Cancer Genomics Program at MD Anderson. The Cancer Genomics Program is directed by Stanley Hamilton, M.D., the Cancer Genomics Core Laboratory is directed by Wei Zhang, Ph.D., and the Department of Bioinformatics and Computational Biology is chaired by John N. Weinstein, M.D., Ph.D. These groups are indebted to valuable contributions made by the personnel of the Genomics Core Lab.
The mission of the Department of Bioinformatics and Computational Biology is to conduct collaborative research with clinical and basic science departments, and to support the need for quantitative sciences in the fields of genomics, proteomics, radiotherapy, molecular and cell biology and computer-assisted diagnoses and image analysis.
The Bioinformatics Group will develop statistically rigorous solutions for the design and analysis of experiments within the Cancer Genomics Program, and will provide data analysis, acquisition, curation and retrieval tools to complement the laboratory services offered by the Cancer Genomics Program.