Lab Members
Han Xu, Ph.D.
Principal Investigator
B.S. and M.S. in Computer Science, Zhejiang University, China
Ph.D. in Bioinformatics, Nanyang Technological University, Singapore
Email: hxu4@mdanderson.org
Research Interests: bioinformatics and computational biology, transcriptional and epigenetic regulation.
Wei He, Ph.D.
Postdoctoral Fellow
B.S. in Biology, The Nanjing University of Science and
Technology, China
Ph.D. in Bioinformatics, The University of
Science and Technology of China, China
Email: whe3@mdanderson.org
Research Interest: Methodology development for
high-throughput biomedical data analysis; multi-omics data
analysis
Current research: Computational
modeling and prediction of CRISPR/Cas9 on-target efficiency and
off-target effects; Computational approaches for understanding
transcriptional and epigenetic regulatory networks.
Liang (Leon) Zhang
Postdoctoral Fellow
B.S. and M.S. in Biochemistry and Molecular Biology, Shandong
Agricultural University, China
Ph.D. in Biochemical Engineering,
University of Chinese Academy of Sciences, China
E-mail: lzhang26@mdanderson.org
Research Interests: Molecular mechanisms of genes
in cancer development and cancer therapy
Current
Research: Using CRISPR screens to identify synthetic
lethality of epigenetic regulators in cancer cells; High-throughput
approaches for characterization of functional domains in transcription
factors and epigenetic regulators.
Rongjie Fu
Postdoctoral Fellow
B.S.
in Biotechnology, Northwest A&F University, China
Ph.D. in
Biochemistry and Molecular Biology, Institute of Health Sciences,
University of Chinese Academy of Sciences, China
Email: rfu1@mdanderson.org
Research interests: Drug resistance in cancer
targeted therapy and immunotherapy
Current
research: The molecular mechanism of CRISPR/Cas9 off-target
effect; Identification of driver factors in cancer drug resistance
using CRISPR screens