Lab Members

Han Xu, Ph.D.
Principal Investigator
B.S. and M.S. in Computer Science, Zhejiang University, China
Ph.D. in Bioinformatics, Nanyang Technological University, Singapore
Email: hxu4@mdanderson.org
Research Interests: bioinformatics and computational biology, transcriptional and epigenetic regulation.

Wei He, Ph.D.
Postdoctoral Fellow
B.S. in Biology, The Nanjing University of Science and Technology, China
Ph.D. in Bioinformatics, The University of Science and Technology of China, China
Email: whe3@mdanderson.org
Research Interest: Methodology development for high-throughput biomedical data analysis; multi-omics data analysis
Current Research: Computational modeling and prediction of CRISPR/Cas9 on-target efficiency and off-target effects; Computational approaches for understanding transcriptional and epigenetic regulatory networks.

Liang (Leon) Zhang
Postdoctoral Fellow
B.S. and M.S. in Biochemistry and Molecular Biology, Shandong Agricultural University, China
Ph.D. in Biochemical Engineering, University of Chinese Academy of Sciences, China
E-mail: lzhang26@mdanderson.org
Research Interests: Molecular mechanisms of genes in cancer development and cancer therapy
Current Research: Using CRISPR screens to identify synthetic lethality of epigenetic regulators in cancer cells; High-throughput approaches for characterization of functional domains in transcription factors and epigenetic regulators.

Rongjie Fu
Postdoctoral Fellow
B.S. in Biotechnology, Northwest A&F University, China
Ph.D. in Biochemistry and Molecular Biology, Institute of Health Sciences, University of Chinese Academy of Sciences, China
Email: rfu1@mdanderson.org
Research Interests: Drug resistance in cancer targeted therapy and immunotherapy   
Current Research: The molecular mechanism of CRISPR/Cas9 off-target effect; Identification of driver factors in cancer drug resistance using CRISPR screens