Publications

Below is a listing of recent publications from the Taniguchi Lab. There are many subprojects from each of the publications below that can be devised for rotating students and summer students that can be tailored to each student based on their interests.

Lin .D, Kouzy R., Abi Jaoude J., Noticewala S., Delgado Medrano A.Y., Klopp A.H., Colbert L.E., Taniguchi C.M.; (2020) Microbiome factors in HPV-driven carcinogenesis and cancers. PLoS Pathog. (Accepted, April 7th, 2020.)

Koay E.J., Hanania A.N., Hal W.A., Taniguchi .C.M, Reubuerno  N., Myrehuag S., Aitken K.L., Dawson L.A., Crane C.H., Herman J.M., Erickson B.; Dose-Escalated Radiation Therapy for Pancreatic Cancer. A Simultaneous Integrated Boost Approach. Pract Radiat Oncol. e-Pub 2/2020. PMID: 32061993

Gronberg M.P., Tailor R.C., Smith S.A., Kry S.F., Followil D.S., Stojadinovic S., Niedzielski J.S.; Lindsay P.E.; Krishnan S., Aguirre F., Fujimoto T.N., Taniguchi C.M., Howell R.M., A Mail Audit Independent Peer Review System for Dosimetry Verification of a Small Animal Irradiator. Radiat Res, e-Pub 2/2020. PMID: 32068498.

Slagowski J.M., Colbert L.E., Cazacu I.M., Singh B.S., Martin R., Koay E.J., Taniguchi C.M., Loong A.C., Bhutani M.S.; Herman J.M., Beddar S.; Evaluation of the VIsibility and Artifacts of 11 Common Fiducial Markers for Image Guided Stereotactic Body Radiation Therapy in the Abdomen. Pract Radiat Oncol. E-Pub 1/2020. PMID 31988039. 

Won Choi, G.; Suh, Y.; Prajnan, D.; Herman, J.; Holliday, E.; Koay E.J.; Koong, A.C.; Krishnan, S.; Minsky, B.D.; Smith, G.L., Taniguchi, C.M. 2019. Assessment of setup uncertainty in hypofractionated liver radiation therapy with a breath-hold technique using automatic image ristration - based image guidance. Radiation Oncology, 14(1); 154. 

Moningi, S.; Jaffer, A.A.; Badgewell, B.D.; Murphy, M.B.; Ikoma, N.; Mansfield, P.F.; Ho, J.C.; Su, Y.; Crane, C.; Herman, J.M.; Holliday E.M.; Koay, E.; Koong, A.C.; Krishnan, S.; Minsky, B.; Smith, BG.; Taniguchi, C.M.; Das, P.; 2019. IMRT Reduces Acute Toxicity in Patients Treated with Preoperative Chemotradiation for Gastric Cancer. Advances in Radiation Oncology. [In Press, Journal Pre-proof]

Moningi, S.; Ludmir E.B.; Polamraju, P.; Williamson, T.; Melkun, M.M., Herman, J.D.; Krishnan, S.; Koay, E.J.; Koong, A.C.; Minsky, B.D.; Smith, G.L; Taniguchi, C.M.; Das, P.; Holliday, E.B.; 2019. Definitive hyperfractionated, accelerated proton reirradiation for patients with pelvic malignancies. Clinical and Translational Radiation Oncology. (1); 69-65. 

Taniguchi, C.M.; Jhingran, A.; Stecklein, S.R.; Melancon, A.; Court, L.; Ohrt, J.; Kupferman, M.E.; Msadabwe, S.C.; 2019. A pilot course of intesnsive training in radiation biology and physics for oncologists in sub-Saharan Africa. Journal of Global Oncology. 5(suppl.); 24. 

Cazacu, I.; Singh, B.; Martin, R.; Slagowski, J.; Beddar, S.; Koay, E.J.; Taniguchi, C.M.; Herman, J.; Bhutani, M.; 2019. Endoscopic Ultrasound-Guided Fiducial Placement for Stereotactic Body Radiation Therapy in Patients with Pancreatic Adenocarcinoma: 923. American Journal of Gastroenterology. 114. 

Slafowski, J.M.; Cazacu, I.M.; Martin, R.; Singh, BAS.; Colbert, L.E.; Koay, E.J.; Taniguchi, C.M.; Koong, A.C.; Herman, J.M.; Bhutani, M.S.; Beddar, S.; 2019. Evaluation of the Visibility and Artifcats of Seven Common Fiducials for Image-Guided Radiation Therapy. Intenational Journal of Radiation Oncology - Biology - Physics, 105(1), E735-E736. 

Park, P.C.; Park, A.J.; Yoon, H.; Damian. A.; Monge, D.; Das, P.; Koay, E.J.; Holliday, E.; Koong, A.C.; Minsky, B.D.; Taniguchi, C.M.; Smith, G.L.; Krishnan, S.; Suh, Y.; Sawakuchi, G.; Beddar, S.; Herman, J.M.; 2019. Patient Setup Management for Pancreatic SBRT: Daily CT Based Assessment of Setup Accuracy using Vertebral Bone, Fiducial Markers, Biliary Stent, and Soft-Tissue Targeting. International Journal of Radiation Oncology - Biology - Physics. 105(1). E770. 

Coronel, E.; Singh, B.S.; Cazacu, I/M.; Moningi, S.; Romero, L.; Taniguchi, C.M.; Herman, J.M.; Bhutani, M.S.; 2019. EUS-guided placement of fiducial markers for the treatment of pancreatic cancer. VideoGIE, 4(9), 403. 

Yu, M; Nguyen, N.D.; Huang, Y.; Lin, D.; Fujimoto, T.N.;Molkentine, J.M.; Deorukhkar, A.; Kang, Y.; San Lucas, F.A.; Fernandes, C.J.; Koay, E.J.; Gupta, S., Ying, H.; Koong, A.C.; Herman, J.M.; Fleming, J.B.; Maitra, A.; Taniguchi, C.M.; 2019. Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer. JCI Insight 4, e126915. (Received Cover).

Bonilla de la Cruz, M.; Stemler, K.M.; Jeter-Jones, S.; Fujimoto, T.N.; Molkentine, J.; Asencio Torres, G.M.; Zhang, Xiaomei.; Broaddus, R.R.; Taniguchi, C.M.; Pwinica-Worms, H. 2019. Fasting reduces intestinal radiotoxicity, enabling dose-escalated radiation therapy for pancreatic cancer. International Journal of Radiation Oncology - Biology - Physics, 105(3); 537-547.

Bernard, V.; San Lucas, F.A.; Huangg, J.; Powell, R.T.; Guerrero, P.A.; Stephan, C.C.; Davies, P.; Varadhachary, G.R.; Katz, M.H.; Taniguchi, C.M.; Alvarez, H.A.; Muthuswamy, S.; Maitra, A.; 2019; Single cell transcriptomic profiling of ex vivo tumoroid models reveal therapeutic vulnerabilities of pancreatic ductal adenocarcinoma. Cancer Research, 79(13), 1402. 

Garcia Garcia, C.J.; Govindaraju, S.; de la Cruz Bonilla, M.; Taniguchi C.M.; 2019; Mechanisms of HIF2-mediated small intestine darioprotection. Cancer Research, 79(13), 3745.

Abu-Gheida, I.; Patel, A.; Zaid, M.; Elganainy, D.; Javle, M.M.; Singh Raghav, K.P.; Vauthey, J.N.; Aloia, T.A.; Tzeng, C.D.; Minsky, B.D.; Smith, G.L.; Holliday, E.B.; Taniguchi, C.M.; Koong, A.; Krsihnan, S.; Herman, J.M.; Prajnan, D.; Crane, C.H.; Koay, E.J.; 2019. Outcomes and patterns of failures after hypodractionated radiation therapy for intrahepatic cholangiocarcinoma. Journal of Clinical Oncology. 37(15). 

Holmlund, J.; Brookes, M.; Colbert, L.E.; Moningi, S.; Bhutani, M.S.; Katz, M.H.; Varadhachary,  G.R.; Thall P.F; Herman, J.M.; Taniguchi, C.M.; 2019, Adaptive Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in combination with GC4419 in pancreatic cancer. Journal of Clinical Oncology. 37(15). 

Bhutani, M. S.; Cazacu, I.M.; Luzuriaga Chavez, A.A.; Singh B.S.; Wong, F.C.L.; Erwin, W.D.; Tamm, E.P.; Mathew, G.G.; Le, D.B.; Koay, E.J.; Taniguchi, C.M.; Minsky, B.D.; Pant, S.; Tzeng, C.D.; Koong, A.C.; Varadhachary, G.R.; Katz, M.H.; Wolff, R.A.; Fogelman, D.R.; Herman, J.M. 2019 Novel EUS-guided brachytherapy treatment of pancreatic cancer with phosphorous-32 microparticles; first United States Experience. VideoGIE. 4(5), 223. 

Fujimoto, T.N.; Colbert, L.E.; Molkentine J.M.; Deorukhkar, A.; Baseler, L.; Bonilla de la Cruz, M.; Yu, M.; Lin, D.; Gupta, S.; Cabeceiras, P.K.; Kingsley, C.V.; Tailor, R.C.; Sawakuchi, G.O.; Koay, E.J.; Piwnica-Worms, H.; Maitra, A.; Taniguchi, C.M. 2019 Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer Research 195610.

Taniguchi CM, Diep, AN, Miao YR, Wu C, Rankin EB, Atwood TA, Xing L, Giaccia AJ. PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2. Science Translation Medicine, 2014 May 12; 6(236):236ra64 (Received Cover).

Taniguchi CM, Finger EC, Krieg, AJ, Wu, C, Diep AN, LaGory EL, Wei K, McGinnis LC, Yuan J, Kuo CJ, Giaccia AJ. Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes. Nature Medicine, 2013 19(10): 1325-1330.

Wei K, Piecewicz S, McGinnis LM, Taniguchi CM, Wiegand S, Chan CW, Mulligan KX, Kuo D, Yuan J, Mortin L, Lefai E, Simon MC, Maher JJ, McGuinness OP, Thurston G, Giaccia AJ, Kuo CJ. A Liver HIF-2 alpha/IRS2 pathway sensitizes insulin signaling and is modulated by VEGF inhibition. Nature Medicine, 2013 19(10): 1331-1337.

Bernard, VB; Semaan, A; Huang, J; San Lucas, FA; Mulu, FC; Stephens, BM; Guerrero, PA; Huang, Y; Zhao, J; Kamyabi, N; Sen, S; Scheet PA; Taniguchi, CM; Kim, MP; Tzeng, CW; Katz MH; Singhi, AD; Maitra, A; Alvarez, HA. Single Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression. BioRxiv 306134 [Preprint].

Huang Y., Lin,D. & Taniguchi, C.M. Sci. China Life Sci. (2017). Hypoxia in the Tumor Microenvironment: Friend or Foe? Published online first: October 13, 2017.

Molkentine, JM; Fujimoto, TN; Horvath, T; Grossberg, AJ; Deorukhkar, A; Samuel, ELG; Chan, WK; Lorenzi, PL; Dantzer, R; Tour, JM; Mason, KA; Taniguchi, CM. Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation. BioRxiv 289074 [Preprint].

Colbert, LE; Rebueno, N; Moningi, S; Beddar, S; Sawakuchi GO; Herman JH; Koong AC; Das, P; Holliday EB; Koay EJ; Taniguchi, CM. Dose Escalation for Locally Advanced Pancreatic Cancer: How High Can We Go? BioRxiv 324129 [Preprint]. May 17, 2018 [cited 2018 May 31].