Research

Lung Cancer & COPD

The research in the Moghaddam Laboratory focuses on airway inflammation and its role in airway epithelial tumorigenesis.

We specifically study the sex and cell type-specific roles of oncogene-driven (intrinsic) and chronic obstructive pulmonary disease-related (extrinsic) lung inflammation in pathogenesis and promotion of Kras mutant lung cancer. 

These projects, by having the potential to detect and target important inflammatory and pro-carcinogenic pathways in the lungs, would have a major impact on prevention and treatment of the leading cause of cancer death.