Research

The research in the Moghaddam Laboratory focuses on airway inflammation and its role in airway epithelial tumorigenesis. We specifically study the sex- and cell type-specific roles of intrinsic (e.g., oncogene-driven) and/or extrinsic (e.g., smoke/electronic cigarette vapor or pathogen-induced) lung inflammation in the pathogenesis and promotion of KRAS-mutant lung cancer. 

These projects, by having the potential to detect and target important inflammatory and pro-carcinogenic pathways in the lungs, would have a major impact on prevention and treatment of the leading cause of cancer death worldwide.