In pursuit of its goals, the Department of Symptom Research employs a translational approach that ranges from bench to bedside and from bedside to bench. Our cross-cutting program integrates both precilincal and clinical research:
- Preclinical and translational research: The department's four Neuroimmunology Laboratories are conducting animal and in vitro studies to discover molecular and cellular mechanisms underlying the symptoms that develop in response to cancer and its treatment — for example, cognitive impairment, pain and fatigue. We are pursuing regenerative medicine and novel agents for treating neurotoxic symptoms.
- Clinical research: The department's Patient-Centered Analytics section engages in observational and interventional studies focused on educational, behavioral, and medical interventions for cancer-related and treatment-related symptoms; creates methodologies for designing, validating, and deploying patient-reported outcomes assessment questionnaires; and develops innovative approaches that use machine learning and artificial intelligence to assess, analyze, and predict patient outcomes.