Tertiary lymphoid structures are highly organized clusters of immune cells that form in non-lymphoid tissues. They’re often found at sites of inflammation, including in a variety of solid tumors. They’re made up of stromal cells as well as a diverse collection of immune cell types in a variety of cell states. Together, tertiary lymphoid structures drive an antitumor immune response. However, they’re not fully understood.
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B cells are an important part of the immune system. One of their jobs is to neutralize the threat from a foreign invader known as a pathogen...
Immunotherapy harnesses the natural power of the immune system and enhances its response to cancer. Immune checkpoint inhibitors are the most...
Cancer research is advancing rapidly, and patients are benefitting from new therapies faster than ever. One example is a type of targeted therapy known as a RET inhibitor.
“A few years ago, we were starting to test these drugs, and now they’re giving patients more time,” says Vivek Subbiah, M.D. Under Subbiah’s direction, the Phase I/II ARROW and the Phase I/II LIBRETTO-001 clinical trials opened at MD Anderson in 2017 to investigate...
The heart pumps blood to send vital oxygen throughout the body. It’s a maze of four chambers: two on the left and two on the right. Blood...
When cancer cells enter the leptomeninges, which are part of the membrane that covers the brain and spinal cord, it can turn into a type of...
Did you know that lymphoma is an umbrella term that includes several subtypes? In general, lymphoma is a cancer that involves immune cells...
Many patients’ goal for cancer treatment is cure. But what if there isn’t a known cure for your diagnosis? That’s the case for patients with...
CD20-targeting monoclonal antibodies and immune checkpoint inhibitors started a revolution in cancer treatment by using immune cells to treat...
Historically, two breast cancer subtypes known as invasive lobular carcinoma and ductal carcinoma have been grouped together. They’ve been...