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BY Clayton Boldt, Ph.D.

First discovered in the 1980s, exosomes are microscopic spherical packages, called vesicles, released by all cells. Their normal role in the body is still being studied, but it is clear to scientists that these virus-sized containers hold a wealth of information about the cells they come from.

Knowing this, researchers are looking to exosomes as tools to screen for cancer, guide treatment strategies and follow how patients respond...

BY Clayton Boldt, Ph.D.

Adoptive cellular therapy is a form of immunotherapy that uses cells from our immune systems, such as T cells, as a treatment for cancer....

BY Clayton Boldt, Ph.D.

Stomach and esophageal cancers are diagnosed in more than 40,000 people each year in the U.S. Most of these cases aren’t detected until the...

BY Clayton Boldt, Ph.D.

Discovering and developing new treatments for cancer is a difficult process with many obstacles. These challenges can slow the process of bringing new therapies to patients. That’s why MD Anderson built the Therapeutics Discovery division, to overcome these hurdles.

This unique team of physicians, researchers, and drug discovery and development experts collaborates across the institution to advance new therapies, providing unique...

Timothy Yap, M.B.B.S., Ph.D., speaks with a patient

BY Clayton Boldt, Ph.D.

Targeted therapies are designed to work against specific vulnerabilities in a cancer cell.

The targeted therapy drug venetoclax is...

BY Clayton Boldt, Ph.D.

For patients with pancreatic cancer, the benefits from immunotherapy treatments with immune checkpoint inhibitors or cell therapies have been...

BY Clayton Boldt, Ph.D.

Last updated on May 21, 2021

Immunotherapy is a treatment option for a growing number of cancers. Unlike traditional treatments like...

BY Clayton Boldt, Ph.D.

Minimal residual disease (MRD) is a term commonly used with blood cancers that describes a small fraction of cancer cells that remain or come...

BY Clayton Boldt, Ph.D.

Layered on top of our genes is an additional set of information -- the epigenome, which is important for many cellular activities. Disruption...

BY Clayton Boldt, Ph.D.

Although a tumor may start from a single cancer cell, it can eventually become millions of cells with unique characteristics. This diversity...