Liver Cancer Diagnosis

Liver cancer often is challenging to diagnose. It usually has no symptoms in the early stages, and tumors often cannot be felt from outside the body. If you have been diagnosed with liver cancer, it is essential to find out exactly where the cancer is and if it has spread. This helps doctors choose the best treatment for you.

Advanced Technology, Techniques

MD Anderson has the most advanced and accurate technology to pinpoint liver cancer, including triple-phase CT scans dedicated to the liver. Many times, spots on the liver that indicate cancer are small, and fine imaging is required to find them.

We have special techniques to find even the smallest spots on the liver. And our staff includes pathologists, diagnostic radiologists and specially trained technicians who are highly skilled in diagnosing liver cancer.

Liver Cancer Diagnostic Tests

If you have symptoms of liver cancer, the first step is a physical exam. The doctor will:

• Feel your abdomen to examine the liver, spleen and nearby organs
  
• Check your abdomen for ascites, an abnormal accumulation of fluid
• Examine your skin and eyes for signs of jaundice

If the doctor suspects liver cancer, you may have one or more of the following tests to diagnose it and find out if it has spread.

Blood tests: One common blood test detects alpha-fetoprotein (AFP), which can be a sign of liver cancer. Other blood tests may measure how well the liver is working.

Imaging tests, which may include:

• CT or CAT (computed axial tomography) scans: This is usually the most reliable test for evaluating the extent of liver cancer. Our technology includes the precise triple-phase CT scan.
• Ultrasound
• Angiogram: The doctor injects dye into an artery. This allows the blood vessels in the liver to be seen on an X-ray.

Biopsy: A sample of tissue from the tumor or the healthy part of the liver is removed and looked at under a microscope. Healthy tissue may be tested to see how well the liver is working. A biopsy may be obtained by:

• Fine needle aspiration (FNA): A thin needle is inserted into the liver to remove a small amount of tissue.
• Core biopsy: This is similar to FNA, but a thicker needle is used to remove small cylinder-shaped samples (cores).
• Laparoscopy: A small incision (cut) is made in the abdomen, and a thin, lighted tube (laparoscope) is inserted to view the tumor.
• Surgical biopsy: Tissue is removed during an operation.

Visit the Prevention section of our website to find out steps you can take to avoid cancer.