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Cytogenetic Technology

Cytogenetic technologists study the structure of human chromosomes and the role of specific changes in the diagnosis and monitoring of acquired and inherited abnormalities.

Degree Offered

Bachelor of Science Degree in Cytogenetic 

The program is administered by:

  • Dean: Shirley Richmond, Ed.D.
  • Program Director: Jun Gu, M.D., Ph.D., CG(ASCP)CM
  • Education Coordinator: Vicki L. Hopwood, M.S.,CG(ASCP)CM, MB (ASCP)
  • Clinical Coordinator: Ming Zhao, M.D., CG(ASCP)CM, MB (ASCP)
  • Medical Advisor: Xinyan Lu, M.D., FACMG

Roster of Faculty

Faculty MemberDegree and SchoolTeaching Assignments
Jun Gu
CG(ASCP)CM
Assistant Professor
M.D., Medical School of Zhejiang University,
Ph.D.
TUI University
  • Clinical Cytogenetics
  • Prenatal/Postnatal Cytogenetics
  • Introduction to G-Band Karyotyping
Vicki L. Hopwood
CG(ASCP)CM
Assistant Professor
M.S.
The University of Texas Graduate School of Biomedical Sciences
  • Genetics of Hematologic Disease
  • Special Topics in Genetics
  • Cytogenetic Lab Techniques
  • Research Seminar
  • Medical Genetics
Peter Hu
MLS(ASCP)CMCGCMMBCM
Associate  Professor
Ph.D.
TUI University
  • Molecular Genetics
  • Medical Genetics
Awdesh Kalia
Assistant Professor
Ph.D.
All India Institute of Medical Sciences
New Delhi, India
  • Basic Techniques Lab
  • Molecular Techniques Lab
  • Advanced Medical Genetics

Adjunct faculty:

Diana Anderson
Lecturer
M.A.
University of Phoenix
  • Diversity and Cultural Competence
Mary Ann Ball
Lecturer
Ph.D.
School of Medicine Indianapolis
  • Diversity and Cultural Competence
Sau Wai Cheung
Professor
Ph.D., School of Medicine Indianapolis
  • Prenatal/Postnatal Cytogenetics
Lawrence Frimpong
CG(ASCP)cm
Lecturer
MBA, B.S.
Texas Women’s University
  • Oncology Cytogenetics
Colleen Gallagher
Assistant Professor
Ph.D.
The Union Institute & University
  • Issues in Health Care Ethics
Jaime Garcia-Heras
Assistant Professor
M.D., Ph.D.
La Plata University School of Medicine
Argentina
  • Oncology Cytogenetics
  • Prenatal/Postnatal Cytogenetics
Gary Lu,
FACMG
Assistant Professor
M.D.,
Sun Yat-Sen University of Medical Sciences
P.R.China
  • Oncology Cytogenetics
Xinyan Lu
Assistant Professor
M.D.
Suzhou Medical College
P.R. China
  • Oncology Cytogenetics
Atousa Maleki
FACMG, CG(ASCP)CM
Assistant Professor
Ph.D.
The University of Texas Graduate School of Biomedical Sciences
  • Clinical Cytogenetics
Reza Marvdashti
Professor
Ph.D.
University of Manchester
Manchester, England
  • Genetics
  • Microbiology
Kimberly Murray
Instructor
M.A.
University of Phoenix
  • Hematology
Ankita Patel
Associate Professor
Ph.D.
Eastern Virginia Medical School
  •  Clinical Cytogenetics
Sen Pathak
Research Professor
Ph.D.
Banaras Hindu University
  • Cytogenetics
Janice L. Smith
Assistant Professor
Ph.D.
University of Alabama
  • Prenatal/Postnatal Cytogenetics

 

Program in Cytogenetics

Mission

The MD Anderson Cancer Center Program in Cytogenetic Technology, in concert with the mission and vision of The University of Texas MD Anderson Cancer Center, is committed to the education of technically and academically competent graduates prepared to meet the immediate and future needs of the Cytogenetic Technology profession.

Objectives

The Cytogenetic Technology program is designed to prepare students to become entry-level clinical cytogenetic technologists. The program provides instruction in all the major areas of clinical cytogenetics including:

  • Prenatal cytogenetics
  • Cancer cytogenetics
  • Molecular techniques
  • The structure of human chromosomes
  • The role of specific changes in the diagnosis and monitoring of acquired and inherited abnormalities

Abnormalities of chromosome number and morphology are linked with over 400 syndromes associated with mental retardation and other phenotypic abnormalities. Identification of these chromosomal abnormalities by cytogenetic technologists provides clinicians in prenatal/postnatal clinics with sufficient information to plan for medical complications that may arise from specific gene defects.

Cancer cytogenetics is a rapidly growing field where the cytogeneticist plays a key role in the diagnosis, prognosis and treatment of both hematological malignancies and solid tumors. World Health Organization (WHO) guidelines require either cytogenetics or molecular genetics for standard workup of leukemias and lymphomas.

Cytogenetic technologists are leaders in the development of applications for new DNA technologies that are transforming modern-day medicine.

Cytogenetic technologists have a wide range of career options in cancer centers, pediatric and genetic counseling clinics, chemical industries, biotechnology companies, research laboratories, molecular cytogenetic laboratories, computer imaging sales and development, pathology labs and research and teaching institutions.

Selection Process

Admission is dependent on factors that include:

  • Cumulative GPA, Science and Math GPA
  • Personal qualities such as maturity and professional goals based on the personal essay, interview, and reference letters.
  • Ability to meet the SHP non-academic technical standards.
    process
  • Race, religion, national origin, veteran status, gender, or disability  are not factors considered in the selection

Applicants should begin the application process three to six months prior to the application deadline to ensure all documents are received and processed by the UTHSC-Houston Registrar’s office. See SHP Academic Calendar for application dates.

Nonacademic Requirements

For a description of the non-academic technical standards requirements for admission, visit the admissions section of the Student Catalog's Policies and Procedures.

Program Admission Requirements

The Bachelor of Science degree program is either a one-year or two-year program with entry at either the junior or senior level. Application and supporting documents must be submitted to the Office of the Registrar. http://registrar.uth.tmc.edu/Admissions/appformslist. Qualified students are accepted on a rolling basis.

Applicants to the Program of Cytogenetic Technology must satisfy the following requirements for admission:

  • All prerequisite course work must be from a regionally accredited college or university.
  • The applicant must have satisfactorily completed all prerequisite courses listed prior to graduating. These courses must be lecture and laboratory courses acceptable toward a degree by majors in those fields and cannot be survey courses.
  • A minimum grade point average of 2.5 on a 4.0 scale both overall and in science and mathematics courses is required to be considered for admission. Special circumstances may be considered, but at the discretion of the Admissions Committee.
  • Texas Success Initiative (TSI) - All applicants must provide proof of successful assessment of the Texas Success Initiative (TSI). Applicants who have graduated with an associate or baccalaureate degree from an accredited Texas College or University are exempt from TSI. Proof of an applicant's readiness to enroll in college level course work will be determined by the Registrar's Office based upon review of official transcripts from previously attended institutions.
  • Test of English as a Foreign Language (TOEFL) - Applicants from countries where English is not the native language may be required to take the TOEFL. Internet based TOEFL is now available and a total test score ranging from 74-78 with a minimum score of 18 in each section is required.

Prerequisites

Prerequisites for the two-year program

A minimum of 60 semester credit hours (SCH) that include:

  • The Texas Core Curriculum – 42 SCH (see table below)
  • An additional - 18 SCH

Within the required 60 SCH, the following must be included:

  • 8  SCH in Biological Sciences 
  • 16 SCH hours in Chemistry

  Note: 12 of the above 24 SCH may be satisfied  by Texas Core Natural Sciences course selection

Prerequisites for the one-year program

A minimum of 90 semester credit hours (SCH)  that include:

  • The Texas Core Curriculum – 42 SCH (see table below)
  • An additional - 48 SCH

 Within the required 90 SCH, the following must be included:

    • 11 SCH of upper level division courses (3000, 4000)
    • 8  SCH in Biological Sciences
    • 16 SCH hours in Chemistry
    • 3 - 4 SCH of Microbiology
    • 3 - 4 SCH of Genetics

 

The Texas Core Curriculum – 42 Semester Credit Hours (SCH) that must include courses from the following specific areas as indicatedSCH

COMMUNICATION (6 SCH)

•           ENGL 1301   English Composition I

•           ENGL 1302   English Composition II

 

 6

MATHEMATICS (3 SCH)

•           MATH 1314   College Algebra or higher

 

 3

NATURAL SCIENCES (12 SCH)

Courses in biology, chemistry, physics, geology or other natural sciences

 

12

HUMANITIES (3 SCH)

Courses in literature, philosophy, modern or classical language/literature, cultural studies or equivalent

 

 3

VISUAL AND PERFORMING ARTS (3 SCH)

Courses in arts, dance, music appreciation, music, drama or equivalent

 

 3

HISTORY (6 SCH)

•           HIST 1301    United States History I

•           HIST 1302    United States History II

 

 6

GOVERNMENT (6 SCH)

•           GOVT 2301   American Government I

•           GOVT 2302   American Government II

 

 6

SOCIAL SCIENCES (3 SCH)

Courses in anthropology, economics, criminal justice, geography, psychology, sociology, social work or equivalent

 

 3
Total Texas Core Curriculum  SCH42

http://statecore.its.txstate.edu/

About the Texas Core Curriculum 

Each institution's Core Curriculum applies to all academic degrees. They range from 42 to 48 credit hours, depending on the college or university. Each Core Curriculum is divided into 8 or 9 categories that are common across the state. If you take the approved Core natural science courses at institution A, they are annotated on your transcript with a Core code by A and must be accepted as fulfilling that portion of the Core at institution B or any other Texas public institution. If Astronomy is a Core natural science at A and is not at B, it must still be accepted at B. This is a whole new way of doing things because the school where you take the course decides how it will transfer. And that decision is binding on any Texas school to which you transfer.

 

Advanced Placement

The School of Health Professions accepts and/or awards credit through the following examination programs:

  • College level examination program of the College Board
  • Comprehensive departmental examinations
  • Regionally accredited military training programs

 

Recommendations from the School's academic departments are followed with regard to minimum score requirements, level of credit, and amount of credit to be awarded.  Program faculty are consulted to determine if credit recommendations equate to specific School of Health Professions (SHP) courses. The internal comprehensive departmental examination program provides a local means for establishing knowledge of SHP course content in areas not covered by the above examination program. Programs may elect to administer examinations that cover material specific to SHP courses with the results being reported to the Registrar.

 Graduation

Each candidate for a baccalaureate degree must complete a minimum of 136 semester credit hours of course work if admitted into the two-year program or a minimum of 139 semester credit hours of coursework if admitted into the one-year program. Within this requirement, students must complete the following at MD Anderson:

  • At least 40 semester hours of advanced (3000/4000) course work
  • At least 25% of the total required semester credit hours

Graduation occurs in August. Upon graduation, students are eligible to take the Clinical Cytogenetics Board of Certification exam given by the American Society for Clinical Pathology (ASCP). Please check with the program director for application deadlines and exam dates. Upon passing this exam, the student is considered a certified cytogenetic technologist. The awarding of the degree or certificate is not contingent upon a student passing the national certification exam.

Curriculum

This intensive program is composed of a didactic phase followed by directed clinical training at affiliated hospitals and laboratories. During the didactic phase, formal lectures are presented on the principles of medical genetics, molecular and biochemical basis of genetic disease, karyotyping, hematology, clinical cytogenetics and molecular genetic technology. Laboratory sessions coordinated with lectures and covering the fundamentals of diagnostic laboratory procedures are included in the didactic phase. Graduates of the program are eligible to take the CG(ASCP) Board of Certification exam

Current Affiliations

The Program in Cytogenetic Technology has developed clinical affiliations with leading clinical cytogenetic laboratories in Texas and beyond in order that students may develop expertise in a variety of settings and experience the breadth of opportunity available to Cytogenetic Technologists. Clinical experiences in these laboratories offer students the opportunity to achieve competence and confidence in performing a wide variety of cytogenetic procedures on patients' specimens

  • Baylor College of Medicine, Houston, TX
  • Center for Medical Genetics, Houston, TX
  • NeoGenomics Inc, Fort Meyers, FL
  • Northwestern University, ACL Laboratories, Chicago, IL
  • Texas Children’s Hospital, Houston, TX
  • The University of Chicago, Chicago, IL
  • The Delta Pathology Group, LLC, Shreveport LA
  • The University of Texas Southwestern Medical Center, Dallas, TX
  • Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
  • Vanderbilt University Medical Center, PathGroup, Nashville, TN

 

Accreditation

The Cytogenetic Technology Program is accredited and has conformed its curriculum to the standards published and monitored by:

National Accrediting Agency for Clinical Laboratory Sciences (NAACLS).
5600 N. River Rd., Suite 720
Rosemont, IL 60018-5119
847-939-3597
773-714-8880
773-714-8886 (Fax)

Course listings

Junior Year: 

The Laboratory Sciences programs admit students at the Junior Year level who share a Junior Year curriculum consisting of:

•           Laboratory sciences core courses

•           Program-specific core courses

•           Program-specific elective courses

Junior Year for Cytogenetic Technology

Cytogenetic Technology (CGT):Junior Year courses 
The Laboratory Sciences shared core courses 
HS 3102 Molecular Techniques Lab1
HS 3210 Laboratory Mathematics2
HS 4310 Medical Microbiology3
HS 4100 Issues in Health Care Ethics1
HS 4101 Diversity and Cultural Competence1
TOTAL CORE COURSES SCH

8

 

 

CGT Program Core 
HS 3120 Introduction to Cytogenetics 1
HS 3270 Critical Thinking in Health Professions 2
HS 3300 Immunology 3
HS 3320 Medical Genetics 3
HS 3330 Pathology of Body Fluids) 3
HS 3333 Statistics 3
HS 3340 Research Methods 3
HS 4300 Pathophysiology 3
HS 4111L Microbiology Lab 1
TOTAL CGT PROGRAM CORE SCH

22

 

 

CGT Program Electives 0
  
  
TOTAL CGT  JUNIOR YEAR SCH

             30

 

Senior Year**

CC 4120 Introduction to G-band Karyotyping1
CC 4152 Prenatal Cytogenetics1
CC 4181 Independent Research Project II1
CC 4210 Molecular and Biochemical Basis of Disease: a Cytogenetic Case-Based Analysis2
CC 4240 Advanced Cytogenetic Laboratory Techniques2
CC 4280 Independent Research Project I2
CC 4320 Special Topics in Genetics3
CC 4450 Clinical Cytogenetics4
CC 4390 Advanced Topics in Cytogenetics3
CC 4521 Prenatal/Postnatal Cytogenetics Clinical Laboratory Rotation5
CC 4530 Basic Laboratory Techniques5
CC 4531 Hematological Cytogenetics Clinical Laboratory Rotation5
GT 4300 Advanced Medical Genetics3
GT 4330 Genetics of Hematological Disease3
HS 4110 Molecular Genetics Technology1
HS 4160 Critical Scientific Analysis1
HS 4161 Seminar in Health Care1
HS 4371 Management and Education3
MG 4199 Special Topics (elective)                                                                        1 hour 
Total46**

**Students entering the School of  Health Professions for the first time at the Senior level must take the following additional required courses that are described in the Junior Year for Laboratory Sciences section of the catalog :

HS 4100 Issues in Health Care Ethics (1)**
HS 4101 Diversity and Cultural Competency 1)** 
HS 4170 Special Topics I**

Course Descriptions

Junior Year 

HS 3102 Molecular Techniques Laboratory (1 semester credit hour)
A study of the laboratory skills involved in transporting, preparing and reporting final results of specimens that include blood, bone marrow and solid tissue samples. The course will provide participants with hands-on laboratory experience in: performing molecular techniques such as DNA extraction, purification and quantification; preparing and viewing PCR products and DNA fingerprints via gel electrophoresis and bacterial transformation. (Admission to Program)

HS 3110 Medical Terminology (1 semester credit hour)
An introduction to medical terminology. Emphasis on word roots, prefixes, suffixes, spelling and analysis of unfamiliar terms. Additional background information on the anatomy that relates to various body systems will be discussed.

HS 3120 Introduction to Cytogenetics (1 semester credit hours)
A detailed study of human G-banded chromosomes. Includes instruction in banding pattern recognition and polymorphic variation. Includes classroom instruction and hands-on experience.

HS 3203 Advanced Molecular Techniques (2 semester credit hours)
This is a continuation of the previous introduction to molecular techniques laboratory course. Emphasis on performing additional molecular techniques such as, but not limited to various DNA extraction methods, amplification methods, electrophoresis, and fluorescent in-situ hybridization.

HS 3210 Laboratory Math (2 semester credit hours)
The basic principles and theory of clinical, biochemical, and analytical laboratory math related calculations.  It includes basic operations such as problem solving using percentiles, rates, ratios, mole ratios, molality, pH, conversions, solving for proportions and more.

HS 3254 Immunohistochemistry (2 semester credit hours)
A comprehensive course that deals with the fundamentals of immunohistochemistry as applied to the theory and practical techniques in histopathology. The students acquire basic knowledge of how immunology is applied in the development of immunohistochemistry reagents and techniques. Emphasis will be placed on the clinical significance of diagnostic and prognostic indicators used in immunohistochemistry techniques. Troubleshooting and standardization of reagents are emphasized.

HS 3270 Critical Thinking in Health Professions (2 semester credit hours)
This course is designed to provide health professions students with resources for improving critical thinking skills. The course will introduce basic concepts of critical thinking through integration into interactive case studies, problem based scenarios, and project design assignments. The specific objectives of this course coincide with the University of Texas MD Anderson Cancer Center School of Health Professions’ definition of critical thinking.

HS 3300 Immunology (3 semester credit hours)
This course focuses on the basic concepts in immunology, and covers general properties of immune responses; cells and tissues of immune system; lymphocyte activation and specificity; effector mechanisms; immunity to microbes; immunodeficiency and AIDS; autoimmune diseases; transplantation. Course delivery is a blend of lecture and on line, self-paced activities.

HS 3310 Introduction to Quality in Healthcare (3 semester credit hours)
This course will provide an overview of the history, development and application of quality concepts. The components of quality management, quality assurance and quality control will be addressed through discussions and assignments on the history of quality, the different approaches to quality, such as Six Sigma and ISO standards, and how to define, implement and ensure compliance to the quality assurance and quality control process.

HS 3320 Medical Genetics (3 semester credit hours)
This course is a study of the role of genetics in medicine including: Mendelian genetics, multifactorial inheritance, DNA structure, chromosome structure, population genetics, mutation rates, ethnicity of disease and genetic mapping. A comprehensive review of the cell cycle, mitosis, and meiosis and pedigree analysis is incorporated as well.  (Admission to Program)

HS 3330 Pathology of Body Fluids (3 semester credit hours)
This course is a study of the anatomy and physiology of the kidney and the formation, elimination and composition of urine. Various body fluids (CSF, Synovial, Plural, Serous, etc.) will be study and associations made with various disease states. Interpretation of urinary and body fluids elements, chemical assays and the correlation with normal and abnormal physiology: Course delivery is a blend of lecture and on line, self-paced activities.  (Admission to Program)

HS 3333 Statistics (3 semester credit hours)
This course provides an introduction to statistical techniques. Emphasis will be placed on probability and probability distributions, sampling and descriptive measures, inference and hypothesis testing, linear regression, and analysis of variance. (Prerequisite HS 3101)

HS 3340 Research Methods (3 semester credit hours)
This research methods course will introduce the basic language and concepts of empirical research with emphasis on the applicability of research methodology in the area of clinical laboratory sciences.  Students will have the opportunity to learn how to search the peer-reviewed journal databases available to them through the Research Library. They will then critique and review their references, learn how to make an outline, and write a literature review on their assigned topic. Curriculum will include a blend of lectures, group work, presentations by guest researchers and development of a group research poster. (Admission to Program)

HS 3370 Fundamentals of Writing and Critical Thinking (3 semester credit hours)
This basic writing course stresses both reading and writing skills and is designed to teach students to improve their ability to write logically and develop short essays, brief formal summaries, and reports.

HS 4100 Issues in Health Care Ethics (1 semester credit hour)
This course content is designed to establish a foundation and set parameters of professional practice for health care professionals. The emphasis will be on developing the background for the resolution of ethical dilemmas through ethical reasoning, ethical obligations in health professional-patient relationships and just allocation of scarce health care resources.

HS 4101 Diversity and Cultural Competence (1 semester credit hour)
This course content is designed to create an awareness of ethnocentrism and a beginning understanding of cultural similarities and diversity. It provides the student with knowledge of the concepts of cultural relativity, cultural integration and variation in cultural values, organization and institutions.

HS 4111L Medical Microbiology Student Laboratory (1 semester credit hour)
The course utilizes biochemical, morphological, and serological techniques to illustrate concepts from the lecture course relating to microbial structure, metabolism, virulence, and transmission.  Students also receive instruction on proper technique and procedures for a number of different tests, including culturing, staining, carbohydrate utilization, immunoassays, and microscopy.

HS 4160 Critical Scientific Analysis (1 semester credit hour)
Students will analyze current scientific publications for research questions, hypothesis, study design and statistical analysis and the application of proper scientific formats in the clinical laboratory professions.  Students will complete pre-session assignments, participate in group discussion & present their group findings.

HS 4161 Seminar in Health Care (1 semester credit hour)
Seminar based course covering topics in the Clinical Laboratory Sciences

HS 4170 Special Topics I (1 semester credit hour)
A review of the principles of mathematics and statistics used in the clinical laboratories, this course presentation includes an introduction to the selection and operation of a laboratory information system.

HS 4300 Pathophysiology (3 semester credit hours)
This course is designed to provide basic knowledge in pathophysiology in preparation for professional studies in the health sciences. Topic covered includes central concepts of pathophysiology of the cells and tissues and alterations on organs and systems with an emphasis on carcinogenesis. Appropriate diagnostic and treatment procedures are covered.

HS 4310 Medical Microbiology (3 semester credit hours)
This course is the study of the utilization of morphological, biochemical, serological, disease inducing characteristics for microorganism, fungi, mycobacterium and virus identification. Course delivery a blend of lecture and on-line, self-paced activities.

HS 4371 Management and Education (3 semester credit hours)
This course covers laboratory management and educational methodologies. It includes management and motivational theories, communication skills, regulatory and accreditation requirements, budget and strategic planning, curriculum design and examination instruction.

Senior Year 

CC 4120 Introduction to G-band Karyotyping (1 semester credit hour)
A detailed study of human G-banded chromosomes. Includes instruction in banding pattern recognition, polymorphic variation, and determination of band level and the International System for Human Cytogenetic Nomenclature (ISCN).  Includes  classroom instruction and hands-on experience.

CC 4152 Prenatal Cytogenetics (1 semester credit hour)
A study of indications for prenatal diagnosis and the procedures used to obtain specimens for such diagnoses: ultrasonography, cordocentesis, amniocentesis and CVS; biochemical assays for metabolic diseases; problems encountered in prenatal chromosome analysis; teratology; and explanations and demonstrations of prenatal cytogenetic techniques and procedures.
Prerequisite: CC 4120

CC 4181 Independent Research Project II (1 semester credit hour)
This course is designed to allow students to have the opportunity to conduct independent research activities with guidance from their faculty advisor. Students are required to submit a formal proposal for review and approval by the program faculty. Prerequisite: CC 4280

CC 4210 Molecular and Biochemical Basis of Disease: a Cytogenetic Case-Based Analysis (2 semester credit hours)
A comprehensive study of cytogenetic disease using case studies. The relationships between molecular defect and the nature of its clinical pathology will be explored through the examination of  biochemical  pathways  affected  such as metabolic, transport, neurological , and muscle and bone. In addition, cytogenetic analysis will be examined through the pre-analytical and analytical, and post-analytical process.  Students will build a foundation of critical decision making and an understanding of the principles of the molecular and biochemical basis of cytogenetic disease.

CC 4240 Advanced Cytogenetic Laboratory Techniques (2 semester credit hours)
A comprehensive study of the cytogenetic analysis of solid tumors. Course includes the study of tumor origin and development, mechanisms of transformation in carcinogenesis and random versus nonrandom findings in human solid tumors. The student will also study the mutagenic effects derived from lifestyle and environmental factors as they relate to malignant disease. This course combines both lecture and laboratory experience into one integrated learning experience. Lab fee of $30.00.

CC 4280 Independent Research Project I (2 semester credit hours)
This course is designed to provide students with an opportunity to independently explore a research area of interest related to cytogenetic  technology.  Students will perform a literature review. Class discussions will explore experimental design and searching the research literature. 

CC 4320 Special Topics in Genetics (3 semester credit hours)
This course will introduce the student to the newest methodologies and topics in genetics. Current topics include spectral karyotyping, creation of bac clone FISH probes, DNA sequencing, array comparative genomic hybridization (aCGH) and use of online genetic databases.
Prerequisite: HS 4110

CC 4390 Advanced Topics in Cytogenetics (3 semester credit hours)
This will be a capstone course where students work on case studies to develop their problem solving skills in a clinical cytogenetic environment. Students will also participate in a national review in clinical cytogenetics. Finally, students will show mastery of the field of cytogenetics through practice exams and eventually taking a comprehensive cytogenetic exam. Prerequisite: GT 4300

CC 4450 Clinical Cytogenetics (4 semester credit hours)
A comprehensive study of chromosome morphology and terminology, general principles of clinical cytogenetics, abnormalities of chromosome number and structure, disorders of autosomes, sex chromosome disorders, the X chromosome, the Y chromosome, congenital versus acquired abnormalities and the ISCN. Students will perform slide analysis of peripheral blood and bone marrow cases. Laboratory fee of $30.00.
Prerequisite: GT 4300

CC 4521 Prenatal/Postnatal Cytogenetics Clinical Laboratory Rotation (5 semester credit hours)
This laboratory rotation complements, expounds on and practically applies the study of cytogenetic procedures and techniques used in prenatal and postnatal diagnosis of chromosomal disorders. This laboratory rotation also provides the students an opportunity to observe and participate in the testing algorithms and reflex testing that occur in this type of cytogenetic testing environment. Laboratory fee of $30.00
Prerequisite: CC 4152

CC 4530 Basic Laboratory Techniques (5 semester credit hours)
A comprehensive study of maintaining laboratory quality control in accordance with federal, state and local regulations, as well as College of American Pathologist on-site inspections and proficiency testing. Also, a study of laboratory skills as they apply to amniotic fluid, chorionic villus sampling, abortus tissue, blood, bone marrow and solid tissue samples with respect to transporting, preparing, culturing, harvesting, banding, analyzing, photographing, karyotyping and reporting final results of specimens. Students will also be instructed in fluorescent in situ hybridization techniques and computer imaging of cytogenetic specimens. Laboratory fee of $30.00.
Prerequisite: GT 4300

CC 4531 Hematological Cytogenetics Clinical Laboratory Rotation (5 semester credit hours)
This laboratory rotation provides the student with comprehensive practical applications in all aspects of the cytogenetic study of hematological malignant disease: specimen preparation, culture and harvest, banding techniques, microscopic cell analysis, photographic techniques, karyotype preparation, evaluation, probe application and ISCN. Quality control procedures and safety considerations are stressed. Laboratory fee of $30.00.
Prerequisite: GT 4330

GT 4300 Advanced Medical Genetics (3 semester credit hours)
A study of the role of genetics in medicine. This course will allow the students to understand the basic genetic principles and their applications in clinical genetics. This course focuses on applying genetic principle in real clinical situations

GT 4330 Genetics of Hematological Disease (3 semester credit hours)
A comprehensive study of the principles and procedures used in the genetic analysis of peripheral blood and bone marrow in the study of malignant processes. The course emphasizes the genetic abnormalities occurring in leukemias and lymphomas and their clinical significance. Students will learn a multidisciplinary approach in the interpretation of disease diagnosis, prognosis and progression by learning how to integrate morphology, pathology and flow test results together with genetic changes.

HS 4100 Issues in Health Care Ethics (1 semester credit hour)
This course content is designed to establish a foundation and set parameters of professional practice for health care professionals. The emphasis will be on developing the background for the resolution of ethical dilemmas through ethical reasoning, ethical obligations in health professional-patient relationships and just allocation of scarce health care resources.

HS 4101 Diversity and Cultural Competence (1 semester credit hour)
This course is designed to provide each student with a fundamental  understanding of  the concepts of cultural competency, diversity, and inclusion. The course content of each module emphasizes the following seven culturally competent areas of diversity: Building Relationships across Culture; Communication Across Differences; Conflict resolution Across Cultures ; Microinequities within the Workplace;. Diversity and Inclusion;  Abilities: A Journey from Exclusion to Inclusion; Spirituality and health care practices.

HS 4110 Molecular Genetics Technology (1 semester credit hour)
The study of clinical laboratory molecular diagnostic procedures utilizing recombinant DNA technology and its application to the many aspects of the clinical laboratory.
Prerequisite: GT 4230, CC 4531

HS 4160 Critical Scientific Analysis (1 semester credit hour)
Student will analyze current scientific  publications for research questions, hypotheses, study design and statistical analysis, and the application of proper scientific formats in the clinical laboratory professions. Students will complete pre-session assignments, participate in group discussions & present their group findings.

HS 4161 Seminar in Health Care (1 SCH)
Seminar-based course covering topics in the clinical laboratory sciences

HS 4170 Special Topics I (1 semester credit hour)
A review of the principles of mathematics and statistics used in the clinical laboratories. Course presentation includes introduction to the selection and operation of a laboratory information system.

HS 4371 Management and Education (3 semester credit hours)
This course covers laboratory management and educational methodologies. It includes management and motivational theories, communication skills, regulatory and accreditation requirements, budget and strategic planning, curriculum design and examination instruction. Course delivery is on-line, interactive, self-paced.

MG 4199 Special Topics 
An independent study of scientific literature. Literature Review of current topics emphasized.


© 2014 The University of Texas MD Anderson Cancer Center