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Faculty Research Interests

Alphabetical List of Faculty

Genetics, Genomics and Epigenetics

Swathi Arur, Ph.D.

regulation and execution of RAS-ERK signaling; germ cell development; C. elegans genetics

Gábor Balázsi, Ph.D.

synthetic biology; non-genetic variation; gene regulatory networks; experimental evolution; mechanisms of drug resistance

Michelle Barton, Ph.D.

chromatin; p53; embryonic stem cells; liver regeneration; breast cancer

Richard R. Behringer, Ph.D.

mammalian developmental genetics; reproductive biology and disease; stem cells, homeostasis, and regeneration; evolution and development

Russell Broaddus, M.D., Ph.D.

endometrial cancer invasion; identification of novel biomarkers for clinical molecular diagnostics; hereditary endometrial cancer

Benoit de Crombrugghe, M.D.

transcriptional control of cartilage and bone formation; contribution to bone formation by transdifferentiation of chondrocytes; epigenetic control of bone formation

Michael Galko, Ph.D.

Drosophila genetics; molecular genetics of tissue repair; cell migration; cell signaling and signal transduction; pain sensitization

Howard B. Gutstein, M.D.

signal transduction mechanisms underlying narcotic tolerance and dependence; development of more effective methods to treat pain; proteomic approaches to pain, narcotic tolerance, and addiction

Vicki Huff, Ph.D.

human genetics; cancer genetics; familial cancer predisposition; kidney development

Randy L. Johnson, Ph.D.

mouse genetics; Hippo pathway; tumor suppressor genes; mouse models for cancer research

Ralf Krahe, Ph.D.

human and molecular genetics; cancer genetics; neurogenetics; genomics; mouse models

Leslie Krushel, Ph.D.

RNA; protein synthesis; Alzheimer's disease; neuronal development

Guillermina (Gigi) Lozano, Ph.D.

tumor suppressors; mouse models; apoptosis

Angabin Matin, Ph.D.

germ cell tumors; biology of germ cells; genetic dissection of cancer susceptibility; mouse models

William Mattox, Ph.D.

RNA biology; germ cell development; genetic models of disease

Gregory S. May, Ph.D.

fungal genetics; fungal pathogenesis; signal transduction

Lalitha Nagarajan, Ph.D.

human cancer; stem cell; mouse models

Nicholas Navin, Ph.D.

single cell genomics; tumor heterogeneity; genome evolution

Jill M. Schumacher, Ph.D.

cell cycle; genome stability; mitotic kinases; Aurora kinases; C. elegans; breast and ovarian cancer

Xiaobing Shi, Ph.D.

cancer epigenetics; chromatin dynamics; histone modifications; transcription

Eric C Swindell, Ph.D.

zebrafish developmental genetics; developmental neuroscience; vascular development; craniofacial development

Kenneth Tsai, M.D., Ph.D.

immunology of skin cancer; MAP kinase pathways in melanoma; genetic basis of skin cancer progression; establishment of skin as a surrogate biomarker

Jessica Tyler, Ph.D.

epigenetics; gene expression; DNA repair; aging

 

Cancer Biology

Gábor Balázsi, Ph.D.

synthetic biology; non-genetic variation; gene regulatory networks; experimental evolution; mechanisms of drug resistance

Russell Broaddus, M.D., Ph.D.

endometrial cancer invasion; identification of novel biomarkers for clinical molecular diagnostics; hereditary endometrial cancer

Jichao Chen, Ph.D., M.H.S.

lung development; organ size control; lung cancer

Giulio F. Draetta, M.D., Ph.D.

Elsa R. Flores, Ph.D.

mouse models; tumor suppressor genes; metastasis; stem cells

Andrew B. Gladden, Ph.D.

cell polarity; metastasis; cell adhesion; stem cell biology

Randy L. Johnson, Ph.D.

mouse genetics; Hippo pathway; tumor suppressor genes; mouse models for cancer research

Ralf Krahe, Ph.D.

human and molecular genetics; cancer genetics; neurogenetics; genomics; mouse models

Mong-Hong Lee, Ph.D.

cell cycle; ubiquitination; 14-3-3 and cancer; gene knock-out; p53 signaling

Randy Legerski, Ph.D.

cellular responses to DNA damage; DNA repair; cell cycle checkpoint signaling

Guillermina (Gigi) Lozano, Ph.D.

tumor suppressors; mouse models; apoptosis

Sadhan Majumder, Ph.D.

connection between normal development and disease; adult and embryonic stem cells; brain tumors; mouse models

Pierre D. McCrea, Ph.D.

catenin proteins; developmental and pathologic signaling; canonical-Wnt pathway; stem cells; frog embryos

Rachel Miller, Ph.D.

kidney development; planar cell polarity and Wnt signaling; primary cilia; morphogenesis; frog embryogenesis

Lalitha Nagarajan, Ph.D.

human cancer; stem cell; mouse models

Nicholas Navin, Ph.D.

single cell genomics; tumor heterogeneity; genome evolution

Helen Piwnica-Worms, Ph.D.

cell cycle; metastasis; breast cancer; molecular imaging; PDX models

Jill M. Schumacher, Ph.D.

cell cycle; genome stability; mitotic kinases; Aurora kinases; C. elegans; breast and ovarian cancer

Xiaobing Shi, Ph.D.

cancer epigenetics; chromatin dynamics; histone modifications; transcription

Kenneth Tsai, M.D., Ph.D.

immunology of skin cancer; MAP kinase pathways in melanoma; genetic basis of skin cancer progression; establishment of skin as a surrogate biomarker

Bin Wang, Ph.D.

DNA damage response; genomic instability and cancer; BRCA1 signaling; ubiquitin signaling

 

Stem Cells and Development

Swathi Arur, Ph.D.

regulation and execution of RAS-ERK signaling; germ cell development; C. elegans genetics

Michelle Barton, Ph.D.

chromatin; p53; embryonic stem cells; liver regeneration; breast cancer

Richard R. Behringer, Ph.D.

mammalian developmental genetics; reproductive biology and disease; stem cells, homeostasis, and regeneration; evolution and development

Jichao Chen, Ph.D., M.H.S.

lung development; organ size control; lung cancer

Elsa R. Flores, Ph.D.

mouse models; tumor suppressor genes; metastasis; stem cells

Michael Galko, Ph.D.

Drosophila genetics; molecular genetics of tissue repair; cell migration; cell signaling and signal transduction; pain sensitization

Andrew B. Gladden, Ph.D.

cell polarity; metastasis; cell adhesion; stem cell biology

Vicki Huff, Ph.D.

human genetics; cancer genetics; familial cancer predisposition; kidney development

William H. Klein, Ph.D.

embryo development; transcription factors in development; control of gene expression; gene regulatory networks; stem cell replacement therapy

Yoshihiro Komatsu, Ph.D.

bone development; ciliopathy; craniofacial development; embryogenesis; stem cells

Sadhan Majumder, Ph.D.

connection between normal development and disease; adult and embryonic stem cells; brain tumors; mouse models

Angabin Matin, Ph.D.

germ cell tumors; biology of germ cells; genetic dissection of cancer susceptibility; mouse models

William Mattox, Ph.D.

RNA biology; germ cell development; genetic models of disease

Pierre D. McCrea, Ph.D.

catenin proteins; developmental and pathologic signaling; canonical-Wnt pathway; stem cells; frog embryos

Rachel Miller, Ph.D.

kidney development; planar cell polarity and Wnt signaling; primary cilia; morphogenesis; frog embryogenesis

Eric C Swindell, Ph.D.

zebrafish developmental genetics; developmental neuroscience; vascular development; craniofacial development

 

Biochemistry and Biomolecular Structure

Howard B. Gutstein, M.D.

signal transduction mechanisms underlying narcotic tolerance and dependence; development of more effective methods to treat pain; proteomic approaches to pain, narcotic tolerance, and addiction

Leslie Krushel, Ph.D.

RNA; protein synthesis; Alzheimer's disease; neuronal development

John E. Ladbury, Ph.D.

biophysical analysis; tyrosine kinase signalling; protein complexes; protein-ligand interactions; drug development; structural-thermodynamic correlations

Mong-Hong Lee, Ph.D.

cell cycle; ubiquitination; 14-3-3 and cancer; gene knock-out; p53 signaling

Randy Legerski, Ph.D.

cellular responses to DNA damage; DNA repair; cell cycle checkpoint signaling

Jessica Tyler, Ph.D.

epigenetics; gene expression; DNA repair; aging

Bin Wang, Ph.D.

DNA damage response; genomic instability and cancer; BRCA1 signaling; ubiquitin signaling


© 2014 The University of Texas MD Anderson Cancer Center