Trainee Publications

Throughout their training, residents have many opportunities to participate in prospective protocol studies as well as to conduct retrospective clinical research. The results of such analyses are an integral part of clinical research and have frequently led to major changes in radiotherapy technique and philosophy. Our residents regularly present their research at scientific conferences such as the annual meetings of the American Society for Therapeutic Radiology and Oncology, the Radiological Society of North America and the American Radium Society. Publications resulting from their research efforts can be found in many radiation oncology and other specialty journals.

Bibliography

This bibliography represents published research manuscripts of our current trainees.

Albert JM, Pan IW, Shih YC, Jiang J, Buchholz TA, Giordano SH, Smith BD. Effectiveness of radiation for prevention of mastectomy in older breast cancer patients treated with conservative surgery. Cancer, Aug 13, 2012 [PMID: 22890779 DOI: 10.1002/cncr.27457]

Albert JM, Liu DD, Shen Y, Pan IW, Shih YC, Hoffman KE, Buchholz TA, Giordano SH, Smith BD. Nomogram to predict the benefit of radiation for older patients with breast cancer treated with conservative surgery. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Aug 10, 2012; 30(23): 2837-2843 [PMID: 22734034 PMCID: 3410401 DOI: 10.1200/JCO.2011.41.0076]

Walker GV, Niikura N, Yang W, Rohren E, Valero V, Woodward WA, Alvarez RH, Lucci A, Jr., Ueno NT, Buchholz TA. Pretreatment staging positron emission tomography/computed tomography in patients with inflammatory breast cancer influences radiation treatment field designs. International journal of radiation oncology, biology, physics, Aug 1, 2012; 83(5): 1381-1386 [PMID: 22284689 DOI: 10.1016/j.ijrobp.2011.10.040]

Tsai CJ, Hofstede TM, Sturgis EM, Garden AS, Lindberg ME, Wei Q, Tucker SL, Dong L. Osteoradionecrosis and Radiation Dose to the Mandible in Patients With Oropharyngeal Cancer.International journal of radiation oncology, biology, physics, Jul 12, 2012 [PMID: 22795804 DOI: 10.1016/j.ijrobp.2012.05.032]

Albert JM, Das P. Quality assessment in oncology. International journal of radiation oncology, biology, physics, Jul 1, 2012; 83(3): 773-781 [PMID: 22445001 DOI: 10.1016/j.ijrobp.2011.12.079]

Kim MM, Hoffman KE, Levy LB, Frank SJ, Pugh TJ, Choi S, Nguyen QN, McGuire SE, Lee AK, Kuban DA. Prostate cancer-specific mortality after definitive radiation therapy: Who dies of disease? Eur J Cancer, Jul, 2012; 48(11): 1664-1671 [PMID: 22336663 DOI: 10.1016/j.ejca.2012.01.026]

Castle KO, Hoffman KE, Levy LB, Lee AK, Choi S, Nguyen QN, Frank SJ, Pugh TJ, McGuire SE, Kuban DA. Is Androgen Deprivation Therapy Necessary in All Intermediate-Risk Prostate Cancer Patients Treated in the Dose Escalation Era? International journal of radiation oncology, biology, physics, Jul 24, 2012 [PMID: 22836052 DOI: 10.1016/j.ijrobp.2012.06.030]

Albert JM, Swanson DA, Pugh TJ, Zhang M, Bruno TL, Kudchadker RJ, Frank SJ. Magnetic resonance imaging-based treatment planning for prostate brachytherapy. Brachytherapy, Jun 21, 2012 [PMID: 22727474 DOI: 10.1016/j.brachy.2012.03.009]

Kim MM, Kudchadker RJ, Kanke JE, Zhang S, Perkins GH. Bolus electron conformal therapy for the treatment of recurrent inflammatory breast cancer: a case report. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, Summer, 2012; 37(2): 208-213 [PMID: 21978532 DOI: 10.1016/j.meddos.2011.07.004]

Smith GL, Xu Y, Buchholz TA, Giordano SH, Jiang J, Shih YC, Smith BD. Association between treatment with brachytherapy vs whole-breast irradiation and subsequent mastectomy, complications, and survival among older women with invasive breast cancer.JAMA : the journal of the American Medical Association, May 2, 2012; 307(17): 1827-1837 [PMID: 22550197 PMCID: 3397792 DOI: 10.1001/jama.2012.3481]

Kim MM, Dawood S, Allen P, Sahin AA, Woodward WA, Smith BD, Strom EA, Hunt KK, Meric-Bernstam F, Gonzalez-Angulo AM, Buchholz TA. Hormone receptor status influences the locoregional benefit of trastuzumab in patients with nonmetastatic breast cancer. Cancer, Apr 17, 2012 [PMID: 22511276 DOI: 10.1002/cncr.27502]

Wang XS, Rhines LD, Shiu AS, Yang JN, Selek U, Gning I, Liu P, Allen PK, Azeem SS, Brown PD, Sharp HJ, Weksberg DC, Cleeland CS, Chang EL. Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1-2 trial. The lancet oncology, Apr, 2012; 13(4): 395-402 [PMID: 22285199 DOI: 10.1016/S1470-2045(11)70384-9]

Koay EJ, Lege D, Mohan R, Komaki R, Cox JD, Chang JY. Adaptive/Nonadaptive Proton Radiation Planning and Outcomes in a Phase II Trial for Locally Advanced Non-small Cell Lung Cancer.International journal of radiation oncology, biology, physics, Apr 27, 2012 [PMID: 22543217 PMCID: 3409930 DOI: 10.1016/j.ijrobp.2012.02.041]

Weksberg DC, Palmer MB, Vu KN, Rebueno NC, Sharp HJ, Luo D, Yang JN, Shiu AS, Rhines LD, McAleer MF, Brown PD, Chang EL. Generalizable Class Solutions for Treatment Planning of Spinal Stereotactic Body Radiation Therapy. International journal of radiation oncology, biology, physics, Mar 21, 2012 [PMID: 22445000 DOI: 10.1016/j.ijrobp.2011.12.060]

Walker GV, Li J, Mahajan A, McAleer MF, de Groot JF, Azeem SS, Brown PD. Decreasing radiation therapy utilization in adult patients with glioblastoma multiforme: A population-based analysis. Cancer, Feb 22, 2012 [PMID: 22359097 DOI: 10.1002/cncr.27439]

Bian SX, Kuban DA, Levy LB, Oh J, Castle KO, Pugh TJ, Choi S, McGuire SE, Nguyen QN, Frank SJ, Nguyen PL, Lee AK, Hoffman KE. Addition of short-term androgen deprivation therapy to dose-escalated radiation therapy improves failure-free survival for select men with intermediate-risk prostate cancer. Ann Oncol, Feb 21, 2012 [PMID: 22357249 DOI: 10.1093/annonc/mds001]

Koay E, Sulman EP. Management of brain metastasis: past lessons, modern management, and future considerations. Current oncology reports, Feb, 2012; 14(1): 70-78 [PMID: 22071681 DOI: 10.1007/s11912-011-0205-9]

Kim MM, Hoffman KE, Levy LB, Frank SJ, Pugh TJ, Choi S, Nguyen QN, McGuire SE, Lee AK, Kuban DA. Improvement in prostate cancer survival over time: a 20-year analysis. Cancer J, Jan-Feb, 2012; 18(1): 1-8 [PMID: 22290249 DOI: 10.1097/PPO.0b013e3182467419]

Welsh J, Palmer MB, Ajani JA, Liao Z, Swisher SG, Hofstetter WL, Allen PK, Settle SH, Gomez D, Likhacheva A, Cox JD, Komaki R. Esophageal cancer dose escalation using a simultaneous integrated boost technique. International journal of radiation oncology, biology, physics, Jan 1, 2012; 82(1): 468-474 [PMID: 21123005 DOI: 10.1016/j.ijrobp.2010.10.023]

Shirvani SM, Komaki R, Heymach JV, Fossella FV, Chang JY. Positron emission tomography/computed tomography-guided intensity-modulated radiotherapy for limited-stage small-cell lung cancer. International journal of radiation oncology, biology, physics, Jan 1, 2012; 82(1): e91-97 [PMID: 21489716 DOI: 10.1016/j.ijrobp.2010.12.072]

Weksberg DC, Bilton SD, Chang EL. Use of a deformable atlas to identify cryptic critical structures in the treatment of glioblastoma multiforme. PloS one, 2012; 7(3): e32098 [PMID: 22461883 PMCID: 3312881 DOI: 10.1371/journal.pone.0032098]

Smith BD, Jiang J, McLaughlin SS, Hurria A, Smith GL, Giordano SH, Buchholz TA. Improvement in breast cancer outcomes over time: are older women missing out? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Dec 10, 2011; 29(35): 4647-4653 [PMID: 22067407 DOI: 10.1200/JCO.2011.35.8408]

Welsh J, Gomez D, Palmer MB, Riley BA, Mayankkumar AV, Komaki R, Dong L, Zhu XR, Likhacheva A, Liao Z, Hofstetter WL, Ajani JA, Cox JD. Intensity-modulated proton therapy further reduces normal tissue exposure during definitive therapy for locally advanced distal esophageal tumors: a dosimetric study. International journal of radiation oncology, biology, physics, Dec 1, 2011; 81(5): 1336-1342 [PMID: 21470796 DOI: 10.1016/j.ijrobp.2010.07.2001]

Walker GV, Ahmed S, Allen P, Gidley PW, Woo SY, DeMonte F, Chang EL, Mahajan A. Radiation-induced middle ear and mastoid opacification in skull base tumors treated with radiotherapy.International journal of radiation oncology, biology, physics, Dec 1, 2011; 81(5): e819-823 [PMID: 21277110 DOI: 10.1016/j.ijrobp.2010.11.047]

Tsai CJ, Crane CH, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Feig BW, Eng C, Krishnan S, Maru DM, Das P. Number of lymph nodes examined and prognosis among pathologically lymph node-negative patients after preoperative chemoradiation therapy for rectal adenocarcinoma. Cancer, Aug 15, 2011; 117(16): 3713-3722 [PMID: 21328329 PMCID: 3266661 DOI: 10.1002/cncr.25973]

Shirvani SM, Kudchadker RJ, Bruno TL, Likhacheva A, Swanson DA, Frank SJ. Impact of urinary catheterization on dosimetry after prostate implant brachytherapy with palladium-103 or iodine-125. Brachytherapy, Jul-Aug, 2011; 10(4): 269-274 [PMID: 21296031 DOI: 10.1016/j.brachy.2010.12.001]

Albert JM, Buzdar AU, Guzman R, Allen PK, Strom EA, Perkins GH, Woodward WA, Hoffman KE, Tereffe W, Hunt KK, Buchholz TA, Oh JL. Prospective randomized trial of 5-fluorouracil, doxorubicin, and cyclophosphamide (FAC) versus paclitaxel and FAC (TFAC) in patients with operable breast cancer: impact of taxane chemotherapy on locoregional control. Breast cancer research and treatment, Jul, 2011; 128(2): 421-427 [PMID: 21553292 DOI: 10.1007/s10549-011-1562-7]

Shirvani SM, Pan IW, Buchholz TA, Shih YC, Hoffman KE, Giordano SH, Smith BD. Impact of evidence-based clinical guidelines on the adoption of postmastectomy radiation in older women.Cancer, Jun 27, 2011 [PMID: 21710653 DOI: 10.1002/cncr.26081]

Welsh J, Amini A, Likhacheva A, Erasmus JJ, Gomez D, Davila M, Mehran RJ, Komaki R, Liao Z, Hofstetter WL, Lee HJ, Bhutani MS, Ajani JA. Update: modern approaches to the treatment of localized esophageal cancer. Current oncology reports, Jun, 2011; 13(3): 157-167 [PMID: 21365188 DOI: 10.1007/s11912-011-0158-z]

Smith BD, Pan IW, Shih YC, Smith GL, Harris JR, Punglia R, Pierce LJ, Jagsi R, Hayman JA, Giordano SH, Buchholz TA. Adoption of intensity-modulated radiation therapy for breast cancer in the United States. Journal of the National Cancer Institute, May 18, 2011; 103(10): 798-809 [PMID: 21525437 DOI: 10.1093/jnci/djr100]

Albert JM, Gonzalez-Angulo AM, Guray M, Sahin A, Tereffe W, Woodward WA, Strom EA, Hunt KK, Tucker SL, Buchholz TA. Patients with only 1 positive hormone receptor have increased locoregional recurrence compared with patients with estrogen receptor-positive progesterone receptor-positive disease in very early stage breast cancer.Cancer, Apr 15, 2011; 117(8): 1595-1601 [PMID: 21472707 DOI: 10.1002/cncr.25694]

Shih YC, Chien CR, Xu Y, Pan IW, Smith GL, Buchholz TA. Economic burden of renal cell carcinoma: Part I--an updated review. PharmacoEconomics, Apr, 2011; 29(4): 315-329 [PMID: 21395351 DOI: 10.2165/11586100-000000000-00000]

Smith GL, Xu Y, Buchholz TA, Smith BD, Giordano SH, Haffty BG, Vicini FA, White JR, Arthur DW, Harris JR, Shih YC. Brachytherapy for accelerated partial-breast irradiation: a rapidly emerging technology in breast cancer care. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Jan 10, 2011; 29(2): 157-165 [PMID: 21135274 DOI: 10.1200/JCO.2009.27.0942]

Likhacheva A, Rosenthal DI, Hanna E, Kupferman M, Demonte F, El-Naggar AK. Sinonasal neuroendocrine carcinoma: impact of differentiation status on response and outcome. Head & neck oncology, 2011; 3: 32 [PMID: 21794118 PMCID: 3154852 DOI: 10.1186/1758-3284-3-32]

Smith BD, Haffty BG, Wilson LD, Smith GL, Patel AN, Buchholz TA. The future of radiation oncology in the United States from 2010 to 2020: will supply keep pace with demand? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Dec 10, 2010; 28(35): 5160-5165 [PMID: 20956628 DOI: 10.1200/JCO.2010.31.2520]

Walker GV, Smith GL, Perkins GH, Oh JL, Woodward W, Yu TK, Hunt KK, Hoffman K, Strom EA, Buchholz TA. Population-based analysis of occult primary breast cancer with axillary lymph node metastasis. Cancer, Sep 1, 2010; 116(17): 4000-4006 [PMID: 20564117 DOI: 10.1002/cncr.25197]

Albert JM, Gonzalez-Angulo AM, Guray M, Sahin A, Strom EA, Tereffe W, Woodward WA, Tucker SL, Hunt KK, Hortobagyi GN, Buchholz TA. Estrogen/progesterone receptor negativity and HER2 positivity predict locoregional recurrence in patients with T1a,bN0 breast cancer. International journal of radiation oncology, biology, physics, Aug 1, 2010; 77(5): 1296-1302 [PMID: 20472353 DOI: 10.1016/j.ijrobp.2009.12.011]

Smith GL, Shih YC, Xu Y, Giordano SH, Smith BD, Perkins GH, Tereffe W, Woodward WA, Buchholz TA. Racial disparities in the use of radiotherapy after breast-conserving surgery: a national Medicare study. Cancer, Feb 1, 2010; 116(3): 734-741 [PMID: 20014181 DOI: 10.1002/cncr.24741]

Smith GL, Shih YC, Giordano SH, Smith BD, Buchholz TA. A method to predict breast cancer stage using Medicare claims. Epidemiologic perspectives & innovations : EP+I, 2010; 7: 1 [PMID: 20145734 PMCID: 2818641 DOI: 10.1186/1742-5573-7-1]

Smith GL, Xu Y, Shih YC, Giordano SH, Smith BD, Hunt KK, Strom EA, Perkins GH, Hortobagyi GN, Buchholz TA. Breast-conserving surgery in older patients with invasive breast cancer: current patterns of treatment across the United States. Journal of the American College of Surgeons, Oct, 2009; 209(4): 425-433 e422 [PMID: 19801315 DOI: 10.1016/j.jamcollsurg.2009.06.363]

Smith GL, Smith BD, Garden AS, Rosenthal DI, Sherman SI, Morrison WH, Schwartz DL, Weber RS, Buchholz TA. Hypothyroidism in older patients with head and neck cancer after treatment with radiation: a population-based study. Head & neck, Aug, 2009; 31(8): 1031-1038 [PMID: 19360741 DOI: 10.1002/hed.21066]

Smith GL, Smith BD, Buchholz TA, Liao Z, Jeter M, Swisher SG, Hofstetter WL, Ajani JA, McAleer MF, Komaki R, Cox JD. Patterns of care and locoregional treatment outcomes in older esophageal cancer patients: The SEER-Medicare Cohort. International journal of radiation oncology, biology, physics, Jun 1, 2009; 74(2): 482-489 [PMID: 19289262 DOI: 10.1016/j.ijrobp.2008.08.046]

Smith GL, Smith BD, Buchholz TA, Giordano SH, Garden AS, Woodward WA, Krumholz HM, Weber RS, Ang KK, Rosenthal DI. Cerebrovascular disease risk in older head and neck cancer patients after radiotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Nov 1, 2008; 26(31): 5119-5125 [PMID: 18725647 DOI: 10.1200/JCO.2008.16.6546]

Kim MM, Mansfield PF, Das P, Janjan NA, Badgwell BD, Phan AT, Delclos ME, Maru D, Ajani JA, Crane CH, Krishnan S. Chemoradiation therapy for potentially resectable gastric cancer: clinical outcomes among patients who do not undergo planned surgery.International journal of radiation oncology, biology, physics, May 1, 2008; 71(1): 167-172 [PMID: 18406886 DOI: 10.1016/j.ijrobp.2007.09.019]

Smith GL, Smith BD, Giordano SH, Shih YC, Woodward WA, Strom EA, Perkins GH, Tereffe W, Yu TK, Buchholz TA. Risk of hypothyroidism in older breast cancer patients treated with radiation.Cancer, Mar 15, 2008; 112(6): 1371-1379 [PMID: 18213620 DOI: 10.1002/cncr.23307]

Kim MM, Rana V, Janjan NA, Das P, Phan AT, Delclos ME, Mansfield PF, Ajani JA, Crane CH, Krishnan S. Clinical benefit of palliative radiation therapy in advanced gastric cancer.Acta Oncol, 2008; 47(3): 421-427 [PMID: 17899453 DOI: 10.1080/02841860701621233]