Areas of Research
- Myelodysplastic Syndrome
- Cancer Biology
- Molecular Biology
- Single-Cell Genomics
Welcome to the Colla Lab at MD Anderson Cancer Center. We are a basic and translational lab in the Leukemia department. Our researchers use multidisciplinary approaches and model systems to gain a deep understanding of the cellular and molecular mechanisms that drive hematologic malignancies (blood cancers).
Our goal is to improve the clinical outcome of patients with Myelodysplastic Syndromes (MDS) and Multiple Myeloma (MM) by making scientific advances that allow us to better understand the molecular mechanisms that drive these hematological malignancies.
- Identify biological mechanisms of therapeutic resistance and develop successful strategies to overcome this resistance
- Leverage insights from basic studies to identify targetable networks
- In vivo analysis to test drug efficacy to develop novel therapies
To develop novel treatment strategies, our research employs an integrative toolbox that includes genomic, molecular, proteomic and cellular analyses, as well as PDX and GEM mouse models.
Funding support for the Colla Laboratory includes the Leukemia and Lymphoma Society, MD Anderson Cancer Center Moon Shots Program®, National Institutes of Health/National Cancer Institute and Evans MDS Foundation.