Study #2019-1223
A Dual Phase 1/2 Study to Determine the Maximum Tolerated Dose, Safety, and Efficacy of 186Rhenium Nanoliposomes (186RNL) in Recurrent Glioma
MD Anderson Study Status
Enrolling
Treatment Agent
Rhenium Liposome Treatment
Description
This is a multi-center, sequential cohort, open-label, volume and dose escalation study of the safety, tolerability, and distribution of 186RNL given by convection enhanced delivery to patients with recurrent or progressive malignant glioma after standard surgical, radiation, and/or chemotherapy treatment. The study uses a modified Fibonacci dose escalation, followed by an expansion at the maximum tolerated dose (MTD) to determine efficacy. The starting absorbed dose is 1mCi in a volume of 0.660mL.
Resources and Links
Phone Number: 1-877-MDA-6789
Information and next steps
Disease:
Glioma
Study phase:
Physician name:
Jeffrey Weinberg
Department:
Neurosurgery
For general questions about clinical trials:
1-877-632-6789
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