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Childhood Osteosarcoma

Osteosarcoma is a bone tumor that consists of malignant cells that produce immature bone. It is the most common type of bone cancer in children and adolescents and affects more males than females. Nearly 80% of osteosarcomas appear in the distal femur, the portion of the thigh bone closest to the knee, or the proximal tibia, the lower leg bone near the knee. Osteosarcoma may also develop in the proximal humerus, the upper arm bone connected to the shoulder.

Of all childhood cancers, osteosarcoma is rare, but it is the most common bone tumor in children; it affects approximately 400 children under age 20 every year.

Osteosarcomas are classified as low, intermediate or high-grade tumors. A low-grade osteosarcoma has few dividing cells in the tumor, while a high-grade osteosarcoma is filled with dead tumor cells. Most tumors that occur in children are high-grade.

If your child has been diagnosed with osteosarcoma, we’re here to help. Call 1-877-632-6789 to make an appointment or request an appointment online.

Why Choose MD Anderson?

  • The Children’s Cancer Hospital is within one of the top-ranked cancer centers in America
  • Access to novel therapies and state-of-the-art technologies before most children’s hospitals
  • We see more types of cancer than any other children’s hospital in Texas
  • Family-centered care that actively involves parents in their child’s treatment
  • A strong cancer research program focused on developing new therapies for pediatric patients
  • Comprehensive support services such as an accredited school program, creative arts, child life and career counseling
  • An Adolescent and Young Adult Program that specializes in the unique medical and psychological needs of patients aged 15-25

Childhood Osteosarcoma Knowledge Center

Treatment at MD Anderson

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