Driving Directions to MD Anderson

Access - An interactive guide for custom driving and walking directions to and around the MD Anderson campus.

Houston Real-Time Traffic Report - This continually updated website helps drivers keep track of traffic hot spots throughout the city of Houston.

MapQuest Map - 1515 Holcombe Boulevard, Houston, TX 77030 (Main Building)

Basic Driving Directions from Houston Highways

• Maps: Overview of Houston, Texas Medical Center

From Bush Intercontinental Airport / U.S. 59 - Traveling South

1. Take Will Clayton Boulevard east to U.S. 59.
2. Turn right (south) on U.S. 59 and follow it to Texas 288.
3. Exit onto Texas 288 and follow it south to the N. MacGregor exit.
4. Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard.
5. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
6. Follow Braeswood to Holcombe Boulevard.
7. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

From Hardy Toll Road - Traveling South

1. Take Hardy Toll Road south to Interstate 610 east.
2. Follow I-610 East and exit onto U.S. 59 South.
3. From U.S. 59 exit onto Texas 288 and follow it south to the N. MacGregor exit.
4. Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard.
5. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
6. Follow Braeswood to Holcombe Boulevard.
7. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

From U.S. 59 - Traveling North

1. Exit onto Texas 288 and follow it south to the N. MacGregor exit.
2. Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard.
3. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
4. Follow Braeswood to Holcombe Boulevard.
5. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

From Interstate 45 - Traveling South

1. Exit onto U.S. 59 south.
2. From U.S. 59, exit onto Texas 288 and follow it south to the N. MacGregor exit.
3. Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard.
4. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
5. Follow Braeswood to Holcombe Boulevard.
6. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

From Hobby Airport / Interstate 45 - Traveling North

1. Take Broadway Street north to Interstate 45.
2. Turn left (north) on I-45 and follow it to Interstate 610.
3. Exit onto I-610 and follow it to the Fannin Street exit.
4. Turn right (north) on Fannin Street and follow it to Holcombe Boulevard.
5. Turn right (east) on Holcombe and follow it to the appropriate Entrance Marker.

From Interstate 10 - Traveling West

1. Exit U.S. 59, heading south.
2. From U.S. 59, exit onto Texas 288 and follow it south to the N. MacGregor exit.
3. Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard.
4. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
5. Follow Braeswood to Holcombe Boulevard.
6. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

From Interstate 10 - Traveling East

1. Exit onto Intertate 45 south.
2. From I-45, exit onto U.S. 59 south.
3. From U.S. 59, exit onto Texas 288 heading south and follow it south to the N. MacGregor exit.
4. Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard.
5. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
6. Follow Braeswood to Holcombe Boulevard.
7. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

From Texas 288 - Traveling North

1. Take the N. MacGregor exit.
2. Turn left (west) onto N. MacGregor and follow it to Braeswood Boulevard.
3. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
4. Follow Braeswood to Holcombe Boulevard.
5. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

From U.S. 290 - Traveling South

1. Merge onto Interstate 610 south.
2. Take I-610 south exit onto Interstate 10 east.
3. From 1-10 exit onto U.S. 59 south.
4. From U.S. 59, exit onto Texas 288 and follow it south to the N. MacGregor exit.
5. Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard.
6. Continue heading straight, onto Braeswood, as N. MacGregor bears right.
7. Follow Braeswood to Holcombe Boulevard.
8. Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker.

Numbered Entry Markers

Entrance 2

• Parking Garage 10
• Self-parking for Main Building, The Art Gallery
• Valet and self-parking for Main Building, The Aquarium (Clark Clinic)

Entrance 3

• Parking Garage 2
• Patient rooms
• Valet and self-parking for Main Building, The Fountain (Alkek Hospital)

Entrance 4

• Parking in McGovern Commons
• Valet and self-parking for Radiation Treatment Center

Entrance 5

• Parking in Mays Clinic/CPB Patient and Visitor Garage
• Self-parking for Mays Clinic, The Tree Sculpture
• Self-parking for the Cancer Prevention Building (CPB), The Star

Entrance 7

• Valet parking for Mays Clinic, The Tree Sculpture
• Valet parking for the Cancer Prevention Building (CPB)  The Star