Skip to Content


Chen J, Saha T, Piao HL, Shukla V, Song S, Dubey N, Tang Y, Jogunoori W, Cao H, Shukla S, B Mishra, Mishra L. E3 ligase Praja1 plays a pivotal role in hepatocellular carcinoma by targeting TGF-beta/Smad signaling pathway. AACR 2012.

Li Y, Majumdar A and Mishra L. CEA induces colorectal cancer metastases by disrupting TGF-beta signaling. AACR 2012

Shukla V, Li Y,   Mishra L. Role of TGF-beta Smad3/4 adaptor protein beta2SP in DNA damage pathways. AACR 2012

Katz LH, Yao Z, Shukla V, Jogunoori W, Peleg S, Shetty K, Curley S, Brown P, Mishra L. Preventive effects of vitamin D in liver cancer. AACR 2012

Song S, Maru DM, Piera-Velazquez S, Stroehlein JR, Davila M, Mishra L.  Dysfunctional of TGF-beta signaling via loss of beta2SP activates SOX9 and C-MYC via Notch signaling in Barrett’s esophageal adenocarcinoma. AACR 2012.

Katz LH, Yao Z,  Vivek S,  Jogunoori W, Peleg S,  Shetty K, Curley S, Brown P, Mishra L, The protective influence of vitamin D in hepatocellular carcinoma. Gastroenterology 2012.

Li Y, Majumdar Lin SH and Mishra L. CEA induces colorectal cancer progression by disrupting TGF-beta signaling. Gastroenterology. 2012.

Shukla V, Li Y, Mishra L. Downregulation of TGF-beta signaling pathway invokes Genomic Instability in Liver Cancers. Gastroenterology. 2012.

Dixit N, Koiri RK, Maurya BK, Trigun SK, Höbartner C, Mishra L.
One pot synthesis of Cu(II) 2,2'-bipyridyl complexes of 5-hydroxy-hydurilic acid and alloxanic acid: synthesis, crystal structure, chemical nuclease activity and cytotoxicity. J Inorg Biochem. 2011 Feb;105(2):256-67. Epub 2010 Nov 13.

Pakala SB, Singh K, Reddy SD, Ohshiro K, Li DQ, Mishra L, Kumar R.
TGF-β1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells. Oncogene. 2011 May 12;30(19):2230-41. Epub 2011 Jan 24.

Mishra L. Health care reform: how personalized medicine could help bundling of care for liver diseases. Hepatology. 2011 Feb;53(2):379-81.

Mendelson J, Song S, Li Y, Maru DM, Mishra B, Davila M, Hofstetter WL, Mishra L.
Dysfunctional transforming growth factor-β signaling with constitutively active notch signaling in Barrett's esophageal Adenocarcinoma. Cancer. 2011 Feb 8. doi: 10.1002/cncr.25861. [Epub ahead of print]

Thenappan A, Shukla V, Abdul Khalek FJ, Li Y, Shetty K, Liu P, Li L, Johnson RL, Johnson L, Mishra L. Loss of transforming growth factor β adaptor protein β-2 spectrin leads to delayed liver regeneration in mice. Hepatology. 2011 May;53(5):1641-50. doi: 10.1002/hep.24111.

Baek HJ, Pishvaian MJ, Tang Y, Kim TH, Yang S, Zouhairi ME, Mendelson J, Shetty K, Kallakury B, Berry DL, Shin KH, Mishra B, Reddy EP, Kim SS, Mishra L.  Transforming growth factor-β adaptor, β2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer. Hepatology. 2011 May;53(5):1676-84.

Li Y, Cao H, Jiao Z, Pakala SB, Sirigiri DN, Li W, Kumar R, Mishra L.Carcinoembryonic antigen interacts with TGF-β receptor and inhibits TGF-β signaling in colorectal cancers. Cancer Res. 2010 Oct 15;70 (20):8159-68.

Yao ZX, Jogunoori W, Choufani S, Rashid A, Blake T, Yao W, Kreishman P, Amin R, Sidawy AA, Evans SR, Finegold M, Reddy EP, Mishra B, Weksberg R, Kumar R, Mishra L (2010). Epigenetic Silencing of beta-Spectrin, a TGF-β Signaling/Scaffolding Protein in a Human Cancer Stem Cell Disorder: Beckwith-Wiedemann Syndrome. J Biol Chem. 2010 285(46):36112-20.

Thenappan A, Li Y, Kitisin K, Rashid A, Shetty K, Johnson L, and Mishra L(2010). The role of TGF-β signaling and expansion of progenitor cells in regenerating liver. Hepatology: 51:1373-82.

Lin L, Amin R, Gallicano GI, Glasgow E, Jogunoori W, Jessup JM, Zasloff M, Marshall JL, Shetty K, Johnson, He AR, Mishra L, (Co-corresponding author) (2009). The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-beta signaling. Oncogene, 28(7):961-72.

© 2015 The University of Texas MD Anderson Cancer Center