Skip to Content


Peer-Reviewed Original Research Articles 

Yates JL, Racine R, McBride KM, Winslow GM. T Cell-Dependent IgM Memory B Cells Generated during Bacterial Infection Are Required for IgG Responses to Antigen Challenge. Journal of Immunology 191(3), 6/2013. PMCID: PMC3720767.

Yang Y, McBride K, Hensley S, Lu Y, Chedin F, Bedford M. Arginine methylation facilitates the recruitment of TOP3 to chromatin to prevent R-loop accumulation. Molecular Cell 53(3), 2013. PMCID: PMC[PubMed - in process].

Gazumyan A, Bothmer A, Klein IA, Nussenzweig MC, McBride KM. Activation-induced cytidine deaminase in antibody diversification and chromosome translocation. Adv Cancer Res  2012; 113(113):167-90 

Gazumyan A, Timachova K, Yuen G, Di Virgilio M, Woo E, Chait BT, Nussenzweig MC, McBride KM.  Amino Terminal Phosphorylation of Activation-Induced Cytidine Deaminase Suppresses c-myc-IgH translocations.  Mol Cell Biol  2011 Feb; 31(3):442-9

Yamane A, Resch W, Kuo N, Kuchen S, Li Z, Sun HW, Robbiani DF, McBride KM, Nussenzweig MC, Casellas R.  Deep-sequencing Reveals the Genomic Targets of Activation-Induced Cytidine Deaminase in B lymphocytes.  Nature Immunol. 2011 Jan;12(1):62-9.

Robbiani DF, Bunting S, Fledhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.  Mol Cell 2009 Nov 25;36(4):631-41.

McBride KM, Gazumyan A, Woo EM, Schwickert TA, Chait BT, Nussenzweig MC. Regulation of class switch recombination and somatic mutation by AID phosphorylation. J Exp Med. 2008 Oct;205(11):2585-94.

Dorsett Y, McBride KM, Jankovic M, Gazumyan A, Thai TH, Robbiani DF, Di Virgilio M, San-Martin BR, Heidkamp G, Schwickert TA, Eisenreich T, Rajewsky K, Nussenzweig MC.  MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation. Immunity. 2008 May;28(5):630-8.           

Shen HM, Bozek G, Pinkert CA, McBride KM, Wang L, Kenter A, Storb U.  Expression of AID Transgene Is Regulated in Activated B Cells But Not in Resting B Cells and KidneyMol Immunol, 2008 Apr;45(7):1883-92.

Chatterji M, Unniraman S, McBride KM, Schatz DG. Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation. J Immunol. 2007 Oct;179(8):5274-80.

Callen E, Jankovic M, Difilippantonio S, Daniel JA, Chen HT, Celeste A, Pellegrini M, McBride KM, Wangsa D, Bredemeyer AL, Sleckman BP, Ried T, Nussenzweig M, Nussenzweig A.  ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes.  Cell. 2007 Jul 13;130(1):63-75

Ramiro A, San-Martin BR, McBride KM, Jankovic M, Barreto V, Nussenzweig A, Nussenzweig MC. The role of activation-induced deaminase in antibody diversification and chromosome translocations. Adv Immunol. 2007;94:75-107. 

McBride KM, Gazumyan A, Woo EM, Barreto VM, Robbiani DF, Chait BT, Nussenzweig MC.  Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation. Proc Natl Acad Sci. 2006 Jun;103(23):8798-803.

Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature. 2006 Mar 2;440(7080):105-9.

Liu L, McBride KM, Reich NC. STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3. Proc Natl Acad Sci. 2005 June;102(23):8150-5

McBride KM, Barreto V, Ramiro AR, Stavropoulos P, and Nussenzweig MC.  Somatic hypermutation is limited by CRM1 dependent nuclear export of activation induced deaminase. J Exp Med. 2004 May;199(9):1235-44.

Barreto V, Reina-San-Martin B, Ramiro AR, McBride KM, Nussenzweig MC.  C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Mol Cell. 2003 Aug;12(2):501-8.

McBride KM and Reich NC. The Ins and Outs of STAT1 Nuclear Transport. Science STKE. 2003 Aug;2003(195):RE13. Review.

Brown MT, McBride, KM, Reich NC, Marriott G and Mangel WF. Actin is a cofactor for a viral protease in the cleavage of cytoskeletal proteins.  J Biol Chem 2002 Nov;277(48):46298-303.

McBride KM, Banninger G, McDonald C, and Reich NC. Regulated nuclear import of the STAT1 transcription factor by direct binding of Importin-a.  EMBO J. 2002 Apr;21(7):1754-63.

McBride KM, McDonald C, Reich NC. Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor. EMBO J. 2000 Nov 15;19(22):6196-206.

Kumar KP, McBride KM, Weaver BK, Dingwall C, and Reich NC. Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1. Mol Cell Biol 2000 Jun;20(11):4159-68.

Book Chapters

McBride KM and Reich NC.  Signal Transducers and Activators of Transcription (STATs): Activation and Biology, PB. Sehgal, D.E. Levy and T. Hirano, Eds. Kluwer Academic Press, The Netherlands, chap. 20 (2003)



© 2014 The University of Texas MD Anderson Cancer Center