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Lab Members


Shawn Bratton, Ph.D.
Associate Professor


Education:
B.S., Molecular Biology, The University of Texas, Austin, TX
B.S., Medical Technology, University of Texas Medical Branch, Galveston, TX
Ph.D., Pharmacology and Toxicology, The University of Texas, Austin, TX
Postdoctoral Fellow, Medical Research Council-Toxicology Unit, Leicester, England

Miao-Der (Sophie) Chen
Graduate Student, Pharmacology & Toxicology

My project is focused on determining if cytosolic acidification and cathepsin release, following heat shock-induced ELMP, is important for caspase activation and cell death following heat shock.  

Education:
B.S., Animal Science, National Pingtung University of Science and Technology, Taiwan
M.S., Animal Science, National Pingtung University of Science and Technology, Taiwan

  

Cyndi Joseph

Graduate Student, Molecular Carcinogenesis

My project is focused on elucidating the specific mechanisms through which kinases, such as ERK2 and c-Abl, regulate the activity of the Apaf-1•caspase-9 apoptosome.

Education:
B.S., Biology, Grambling State University, Grambling, LA

  

Daric Wible
Graduate Student, Cell and Molecular Biology

My project is related to autophagy and the molecular mechanism(s) that regulate the formation and maturation of autophagosomes, with a particular emphasis on the role that p38 MAPKs play in this process.

Education:
B.S., Molecular Biology and Biochemistry, University of Colorado, Boulder, CO

  

Chu-Chiao (Chrystal) Wu
Graduate Student, Cell and Molecular Biology

My project is focused on the stoichiometry and dimerization/conformational status of caspase-9 within the Apaf-1 apoptosome complex and its activation mechanism in vivo using a novel caspase-9 knock-in mouse model.

Education:
B.S., Nuclear Science, National Tsing Hua University, Taiwan
M.S., Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Taiwan

  

Ting-Chun Yeh
Graduate Student, Cell and Molecular Biology

My project is focused on understanding how Grim, an endogenous inhibitor of apoptosis (IAP) antagonist in Drosophila, induces IBM-independent apoptosis.

Education:
B.S., Pharmacy, National Taiwan University, Taiwan
M.S., Pharmaceutical Sciences, National Taiwan University, Taiwan

 

© 2014 The University of Texas MD Anderson Cancer Center