Selected Early Publications
Swiercz R, Cheng D, Kim D, Bedford MT. Ribosomal protein rpS2 is hypomethylated in PRMT3-deficient mice. J Biol Chem 282:16917-16923, 2007.
Cheng D, Cote J, Shaaban S, Bedford MT. The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing. Molecular Cell 25:71-83, 2007.
Kim J, Daniel J, Espejo A, Lake A, Krishna M, Xia L, Zhang Y, Bedford MT. Tudor, MBT and chromo domains gauge the degree of lysine methylation. EMBO Rep 7:397-403, 4/2006.
Huang Y, Fang J, Bedford MT, Zhang Y, Xu R-M. Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Science 312:748-751, 2006.
Bedford MT and Richard S. Arginine methylation: An emerging regulator of protein function. Molecular Cell, 18: 263-272, 2005.
Cheng D, Yadav N, King RW, Swanson MS, Weinstein EJ, Bedford MT. Small molecule regulators of protein arginine methyltransferases. J Biol Chem, 279: 23892-23899, 2004.
Kim J, Lee J, Yadav N, Wu Q, Carter C, Richard S, Richie E, Bedford MT. Loss of CARM1 results in hypomethylation of TARPP and deregulated early T cell development. J Biol Chem, 279: 25339-25344, 2004.
Yadav N, Lee J, Kim J, Shen J, Hu MC-T, Aldaz CM, Bedford MT. Specific protein methylation defects and gene expression perturbations in CARM1-deficient mice. PNAS, 100: 6464-6468, 2003.
Frankel A, Yadav N, Lee J, Branscombe TL, Clarke S, Bedford MT. The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity. J Biol Chem, 277: 3537-3543, 2002.
Lee J and Bedford MT. PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays. EMBO Reports, 3: 268-273, 2002.