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Lab Members

Principal Investigator
Mark Bedford
, Professor
M.S. in Medical Biochemistry, University of Stellenbosch, 
South Africa
Ph.D in Developmental Biology, 
Weizmann Institute of Science, Israel 
Postdoctoral Fellowship, Harvard Medical School, 
Dr. Philip Leder


Donghang Cheng, Assistant Research Professor
Originally from China
M.S. from Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Ph.D from National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Current Research: Functional analysis of arginine methyltransferases; identifying and developing specific PRMT inhibitors.


Yanzhong Yang, Postdoctoral Fellow
Originally from China
BS in Pediatrics, Shanxi Medical University
Ph.D in Biochemistry and Molecular Biology, Shanghai Medical College of Fudan University
Current research: I am interested in how protein post-translational modification signals, especially arginine methylation, are transmitted through effector molecules into biological outcomes.


Mahmoud Kahlil, Postdoctoral Fellow
Originally from Alexandria, Egypt
B.S. & M.S. from Alexandria University, Egypt
Ph.D from University College London, UK
Current Research: Developing small molecule inhibitors of epigenetic effector molecules.




Surbhi Dhar, Postdoctoral Fellow
Originally from India
B.Sc. in Microbiology (Hons.), University of Delhi, India
M.Sc. in Biotechnology, Jammu University, India
Ph.D in Chromatin Biology, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), India
Current Research: Identification of monomethylated PRMT1 substrates; generating PRMT5 overexpression mouse model.  


Alessandra Di Lorenzo, Graduate Research Assistant
Originally from the Amalfi Coast, Italy
B.S. & M.S. in Biology, University of Naples Federico II, Italy
Current research: Discovering new biological functions for PRMT6 using gain-of-function mouse models; studying the consequence of PRMT6 over-expression and the effects of elevated histone arginine methylation at the organismal level in two inducible PRMT6 gain-of-function mouse models.  

Alexsandra Espejo, Graduate Research Assistant
Originally from Chile
B.S. in Marine Biology, University of Concepcion, Chile
Current Research: Regulation of epigenetic enzyme PRMT5 by phosphorylation and the effects in its catalytic activity and recruitment of phospho-dependent binding proteins. 


Vidyasiri Vemulapalli, Graduate Research Assistant
Originally from India
B.S. from Vellore Institute of Technology, India
M.S. from The University of Texas at San Antonio
Current Research: Identifying PRMT substrates; regulation of protein function by arginine methylation.


Cari Sagum, Research Assistant
Originally from Houston, Texas
B.S. in Microbiology, The University of Texas at Austin
Current Research: Identifying novel protein-protein interactions using protein domain microarrays.

© 2014 The University of Texas MD Anderson Cancer Center