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Publications

2014

Jain AK, Allton K, Duncan AD , Barton MC (2014) TRIM24 is a p53-Induced E3-Ubiquitin Ligase that undergoes ATM-Mediated Phosphorylation and Autodegradation during DNA Damage. Mol Cell Biol, published ahead of print 12 May 2014, doi: 10.1128/MCB.01705-12. PMID: 24820418

Pathiraja TN, Thakkar KN, Jiang S, Stratton S, Liu Z, Gagea M, Xi S, Shah PK, Phan L, Lee M-H, Andersen J, Stampfer M, Barton MC (2014) TRIM24 Links Glucose Metabolism with Transformation of Human Mammary Epithelial Cells. Oncogene (in press)

Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X (2014) ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression. Nature, 508(7495):263-68. PMID: 24590075

2013

Zhang X, Tanaka K, Yan J, Li J, Peng D, Jiang Y, Yang Z, Barton MC, Wen H, Shi X (2013) Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation. Proc Natl Acad Sci U S A 110(43):17284-89. PMID: 24101509 PMCID: PMC3808627

Akdemir KC, Jain AK, Allton K, Aronow B, Xu X, Cooney AJ, Li W, Barton MC (2013) Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells. Nucl Acids Res 42(1):205-23. PMID: 24078252 PMCID: PMC3874181

Stratton S, Barton MC (2013) The hierarchy of a regenerative cell cycle: Cyclin E1 multi-tasks. Hepatology 59(2):370-71. PMID: 23913250

Kurinna S, Stratton SA, Coban Z, Schumacher JM, Grompe M, Duncan AW, Barton MC (2013) p53 regulates a mitotic transcription program and determines ploidy in normal mouse liver. Hepatology 57(5):2004-13 PMID: 23300120 PMCID: PMC3632650

2012

Jain AK, Barton MC (2012) Unmet Expectations: miR-34 Plays No Role in p53-Mediated Tumor Suppression In Vivo. PLoS Genet 8(7): e1002859. PMID: 22870065 PMCID: PMC3411369

Bochkis IM, Schug J, Ye DZ, Kurinna S, Stratton SA, et al. (2012) Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2. PLoS Genet 8(6): e1002770. PMID: 22737085 PMCID: PMC3380847

Stratton SA, Barton MC (2012) p53-Mediated regulation of hepatic lipid metabolism: forging links between metabolism, atherogenesis, and cancer. J Hepatol 56(3):518-19. PMID: 22051552

Coban Z, Barton MC (2012) Integrative genomics: Liver regeneration and hepatocellular carcinoma. J Cell Biochem 113(7):2179-84. PMID: 22345090 PMCID: PMC3350570

Jain AK, Allton K, Iacovino M, Mahen E, Milczarek RJ, Zwaka TP, Kyba M, Barton MC (2012) p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol 10(2):e1001268. PMID: 22389628 PMCID: PMC3289600

2011

Singh MM, Manton CA, Bhat KP, Tsai WW, Aldape K, Barton MC, Chandra J (2011) Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro Oncol 13(8):894-903. PMID: 21653597 PMCID: PMC3145466

Wilson MA, Koutelou E, Hirsch C, Akdemir K, Schibler A, Barton MC, Dent SY (2011) Ubp8 and SAGA Regulate Snf1 AMP Kinase Activity. Cell Biol 31(15):3126-35. PMID: 21628526 PMCID: PMC3147604

Mao CA, Tsai WW, Cho JH, Pan P, Barton MC, Klein WH (2011) Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development. Dev Biol 349(1):90-99. PMID: 20969844 PMCID: PMC2993882

2010

Tsai W-W, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S, Tsai C-Y, Shi X, Schwarzer D, Plunkett W, Aronow B, Gozani O, Fischle W, Hung M-C, Patel DJ, Barton MC (2010) TRIM24 links a non-canonical histone signature to breast cancer. Nature 468:927-32. PMID: 21164480 PMCID: PMC3058826

Kurinna S, Barton MC (2010) Hierarchies of transcriptional regulation during liver regeneration. Prog Mol Biol Transl Sci 97:201-27. PMID: 21074734

Jain AK, Barton MC (2010) Making sense of ubiquitin ligases that regulate p53. Cancer Biol Ther 10(7):665-72. PMID: 20930521 PMCID: PMC3023569

Kurinna S, Stratton SA, Tsai WW, Akdemir KC, Gu W, Singh P, Goode T, Darlington GJ, Barton MC (2010) Direct activation of forkhead box O3 by tumor suppressor p53 and p73 is disrupted during liver regeneration in mice. Hepatology 52(3):1023-32. PMID: 20564353 PMCID: PMC3741038

Dejosez M, Levine SS, Frampton GM, Whyte WA, Stratton SA, Barton MC, Gunaratne PH, Young RA, Zwaka TP (2010) Ronin/Hcf-1 binds to a hyper-conserved enhancer element and regulates genes involved in the growth of embryonic stem cells. Genes Dev 24(14):1479-84. PMID: 20581084 PMCID: PMC2904937

Taube JH, Allton K, Duncan SA, Shen L, Barton MC (2010) Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem 285(21):16135-44. PMID: 20348100 PMCID: PMC2871482

Kurinna S, Barton MC (2010) Cascades of transcription regulation during liver regeneration. Int J Biochem Cell Biol 43(2):189-97. PMID: 20307684 PMCID: PMC2923255

2009

Jain AK, Barton MC (2009) Regulation of p53: TRIM24 enters the RING. Cell Cycle 8(22):3668-74. PMID: 19844164 Free full text

Minard ME, Jain AK, Barton MC (2009) Analysis of epigenetic alterations to chromatin during development. Genesis 47(8):559-72. PMID: 19603511 PMCID: PMC2751662

Allton K, Jain A, Herz HM, Tsai WW, Jung SY, Qin J, Bergmann A, Johnson RL, Barton M (2009) Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci U S A 106(28):11612-16. PMCID: PMC2710642 PMCID: PMC2710642

2008

Wilkinson DS, Tsai WW, Schumacher MA, Barton MC (2008) Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer TGF-mediated transcription repression. Mol Cell Biol 28:1988-98. PMID: 18212064 PMCID: PMC2268392

Johnson AB, Denko N, Barton MC (2008) Hypoxia induces a novel signature of chromatin modifications and global repression of transcription. Mutation Res 640:174-79. PMID: 18294659 PMCID: PMC2346607

Tsai WW, Nguyen TT, Shi Y, Barton MC (2008) p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo. Mol Cell Biol 28(17):5139-46. PMCID: PMC2519740

Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ (2008) Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci U S A 105(31):10859-64. PMCID: PMC2504784

Cirillo LA, Barton MC (2008) Many Forkheads in the road to regulation. EMBO Rep 9:721-724. PMID: 18617889 PMCID: PMC2515216

2007

Qian J, Steigerwald K, Combs KA, Barton MC, Groden J (2007) Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of of APC in apoptosis. Oncogene 26:4872-76. PMID: 17297457

Chen L, Firozi P, Barton M, Templeton NS (2007) Widespread, exceptionally high levels of histone H3 lysine-4 tri-methylation largely mediate "privileged" gene expression. Gene Expression 13:271-82. PMID: 17605300

Johnson AB and Barton MC (2007) Hypoxia-induced and stress-specific changes in chromatin structure and function. Mutat Res 618(1-2):149-62. PMCID: PMC1924842

2006

Barton MC, Akli S, Keyomarsi K (2006) Deregulation of cyclin E meets dysfunction in p53: closing the escape hatch on breast cancer. J Cell Physiol 209(3):686-94. PMID: 17001684

Barton MC (2006) Influences along the path to maturity: regulation of cellular levels of RNA. Biochim Biophys Acta 1759(8-9):385-87. PMID: 17007943

2005

Cui R, Nguyen TT, Taube JH, Stratton SA, Feuerman MH, Barton MC (2005) Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription. J Biol Chem 280(47):39152-60. PMID: 16203738 Free full text

Park JI, Kim SW, Lyons JP, Ji H, Nguyen TT, Cho K, Barton MC, Deroo T, Vleminckx K, Moon RT, McCrea PD (2005) Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Dev Cell 8(6):843-54. PMID: 15935774

Nguyen TT, Cho K, Stratton SA, Barton MC (2005) Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene. Mol Cell Biol 25(6):2147-57. PMCID: PMC1061614

Wilkinson DS, Ogden SK, Stratton SA, Piechan JL, Nguyen TT, Smulian GA, Barton MC (2005) A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene. Mol Cell Biol 25(3):1200-12. PMCID: PMC544019

Steigerwald K, Behbehani GK, Combs KA, Barton MC, Groden J (2005) The APC tumor suppressor promotes transcription-independent apoptosis in vitro. Mol Cancer Res 3(2):78-89. PMID: 15755874 Free full text

2000-2004

Denko N, Wernke-Dollries K, Johnson AB, Hammond E, Chiang CM, Barton MC (2003) Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly. J Biol Chem 278:5744-49. PMID: 12477712 Free full text

Ogden SK, Lee KC, Wernke-Dollries K, Stratton SA, Aronow B, Barton MC (2001) p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression. J Biol Chem 276:42057-62. PMID: 11572852 Free full text

Ogden SK, Lee KC, Barton MC (2000) Hepatitis B viral transactivator HBx alleviates p53-mediated repression of alpha-fetoprotein gene expression. J Biol Chem 275:27806-14. PMID: 10842185 Free full text

Rockx DA, Mason R, van Hoffen A, Barton MC, Citterio E, Bregman DB, van Zeeland AA, Vrieling H, Mullenders LH (2000) UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II. Proc Natl Acad Sci U S A 97:10503-08. PMID: 10973477 PMCID: PMC27054

Crowe AJ, Piechan JL, Sang L, Barton MC (2000) S-Phase progression mediates activation of a silenced gene in synthetic nuclei. Mol Cell Biol 20:4169-80. PMID: 10805758 PMCID: PMC85786


© 2014 The University of Texas MD Anderson Cancer Center