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Publications

Selected Publications (1999 - Present)

Barnhart KF, Christianson DR, Kolonin MG, Hulvat JF, Chan L, Arap W, Pasqualini R. Response to comment on "a peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys." Sci Transl Med  2012; 4(131):131lr2. Abstract, Full Text

Rotolo JA, Stancevic B, Zhang J, Hua G, Fuller JD, Yin X, Haimovitz-Friedman A, Kim K, Qian MD, Cardo-Vila M, Fuks Z, Pasqualini R, Arap W, Kolesnick R. Anti-ceramide antibody prevents the radiation GI syndrome in mice. J Clin Invest 2012; 122(5).  Abstract, Full Text

Rangel R, Guzman-Rojas L, le Roux LG, Staquicini FI, Hosoya H, Barbu M, Ozawa MG, Nie J, Dunner Jr K, Langley RR, Sage EH, Koivunen E, Gelovani JG, Lobb RR, Sidman RL, Pasqualini R, Arap W. Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells. Nat Commun  2012; 3(788). Abstract, Full Text

Guzman-Rojas L, Rangel R, Salameh A, Edwards JK, Dondossola E, Kim YG, Saghatelian A, Giordano RJ, Kolonin MG, Staquicini FI, Koivunen E, Sidman RL, Arap W, Pasqualini R. Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment. Proc Natl Acad Sci U S A 2012; 109(5):1637-42. Abstract, Full Text

Barnhart KF, Christianson DR, Hanley PW, Driessen WH, Bernacky BJ, Baze WB, Wen S, Tian M, Ma J, Kolonin MG, Saha PK, Do KA, Hulvat JF, Gelovani JG, Chan L, Arap W, Pasqualini R.  A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.  Sci Transl Med 2011; 3(108):108ra112  Abstract, Reprint, Full Text, M.D. Anderson News Release

Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, Gershenwald JE, Molldrem JJ, Flamm AL, Koivunen E, Pentz RD, Dias-Neto E, Setubal JC, Cahill DJ, Troncoso P, Do KA, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc Natl Acad Sci U S A 2011; 108(46):18637-42. Abstract, Full Text

Polf JC, Bronk LF, Driessen WH, Arap W, Pasqualini R, Gillin M. Enhanced relative biological effectiveness of proton radiotherapy in tumor cells with internalized gold nanoparticles. Appl Phys Lett 2011; 98(19):193702. Abstract, Full Text

Arias CA, Panesso D, McGrath DM, Quin X, Mojica MF, Miller C, Diaz L, Tran TT, Rincon S, Barbu EM, Reyes J, Roh JH, Lobos E, Sodergren E, Pasqualini R, Arap W, Quinn JP, Shamoo Y, Murray BE, Weinstock GM.  Genetic basis for in vivo daptomycin resistance in enterococci. N Engl J Med 2011; 365(10):892-900.  Abstract, Full Text

Porto G, Giordano RJ, Marti LC, Stolf B, Pasqualini R, Arap W, Kalil J, Coelho V. Identification of novel immunoregulatory molecules in human thymic regulatory CD4+CD25+ T cells by phage display.  PLoS One 2011; 6(8):e21702. Abstract, Full Text

Carraro DM, Ferreira EN, de Campos Molina G, Puga RD, Abrantes EF, Trape AP, Eckhardt BL, Nunes DN, Brentani MM, Arap W, Pasqualini R, Brentani H, Dias-Neto E, Brentani RR. Poly (A)+ transcriptome assessment of ERBB2-induced alterations in breast cells lines. PLoS One 2011; 6(6):e21022. Abstract, Full Text

Moeller BJ, Sidman RL, Pasqualini R, Arap W. Discovery of DNA repair inhibitors by combinatorial library profiling. Cancer Res 2011; 71(5):1816-24. AbstractFull Text

Corti A, Pastorino F, Curnis F, Arap W, Ponzoni M, Pasqualini R.  Targeted drug delivery and penetration into solid tumors.  Med Res Rev Epub 2011.  Abstract, PDF

Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG 2nd, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Höök M, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W. Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.  J Clin Invest 2011; 121:161-73.  Abstract, PDF

Karjalainen K, Jaalouk DE, Bueso-Ramos CE, Zurita AJ, Kuniyasu A, Eckhardt BL, Marini FC, Lichtiger B, O'Brien S, Kantarjian HM, Cortes JE, Koivunen E, Arap W, Pasqualini R. Targeting neuropilin-1 in human leukemia and lymphoma. Blood 2011; 117:920-7. Abstract, PDF

Gesteira TF, Coulson-Thomas VJ, Taunay-Rodrigues A, Oliveira V, Thacker BE, Juliano MA, Pasqualini R, Arap W, Tersariol IL, Nader HB, Esko JD, Pinhal MA. Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1. J Biol Chem 2011; 286(7):5338-46. Abstract, PDF

Binder M, Müller F, Jackst A, Léchenne B, Pantic M, Bacher U, Eulenburg CZ, Veelken H, Mertelsmann R, Pasqualini R, Arap W, Trepel M. B-cell receptor epitope recognition correlates with the clinical course of chronic lymphocytic leukemia. Cancer 2011; 117(9):1891-900. Abstract, PDF

Staquicini FI, Moeller BJ, Arap W, Pasqualini R. Combinatorial vascular targeting in translational medicine. Proteomics Clin Appl 2010; 4:626-32.  Abstract, PDF

Tonelli RR, Giordano RJ, Barbu EM, Torrecilhas AC, Kobayashi GS, Langley RR, Arap W, Pasqualini R, Colli W, Alves MJ. Role of the gp85/trans-sialidases in Trypanosoma cruzi tissue tropism: preferential binding of a conserved peptide motif to the vasculature in vivo. PLoS Negl Trop Dis 2010; 4:e864. Abstract, PDF

Li J, Gu X, Ma Y, Calicchio ML, Kong D, Teng YD, Yu L, Crain AM, Vartanian TK, Pasqualini R, Arap W, Libermann TA, Snyder EY, Sidman RL. Nna1 mediates purkinje cell dendritic development via lysyl oxidase propeptide and NF-kB signaling. Neuron 2010; 68:45-60.  Abstract, PDF

Souza GR, Staquicini FI, Christianson DR, Ozawa MG, Miller JH, Pasqualini R, Arap W. Combinatorial targeting and nanotechnology applications.  Biomed Microdevices 2010; 12:597-606.  Abstract, PDF

Moeller BJ, Arap W, Pasqualini R.  Targeting synthetic lethality in DNA damage repair pathways as an anti-cancer strategy.  Curr Drug Targets 2010; 11(10):1336-40. Abstract, PDF

Edwards JK, Pasqualini R, Arap W, Calin GA. MicroRNAs and ultraconserved genes as diagnostic markers and therapeutic targets in cancer and cardiovascular diseasess.  J Cardiovasc Transl Res 2010; 3:271-9. Abstract, PDF

Pasqualini R, Moeller BJ, Arap W. Leveraging molecular heterogeneity of the vascular endothelium for targeted drug delivery and imaging. Semin Thromb Hemost 2010; 36:343-51.  Abstract, PDF

Giordano RJ, Cardó-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawk DH, Valente AP, Almeida FCL, Nör JE, Sidman RL, Pasqualini R, Arap W. From combinatorial peptide selection to drug prototype (I): Targeting the vascular endothelial growth factor receptor pathway. Proc Natl Acad Sci U S A. 2010; 107:5112-7. Abstract, PDF, Commentary

Cardo-Vila M, Giordano RJ, Sidman RL, Fan Z, Mendelsohn J, Arap W, Pasqualini R. From combinatorial peptide selection to drug prototype: (II) Targeting the epidermal growth factor receptor pathway. Proc Natl Acad Sci U S A. 2010; 107:5118-23. Abstract, PDF

Loi M, Marchiò S, Becherini P, Di Paolo D, Soster M, Curnis F, Brignole C, Pagnan G, Perri P, Caffa I, Longhi R, Nico B, Bussolino F, Gambini C, Ribatti D, Cilli M, Arap W, Pasqualini R, Allen TM, Corti A, Ponzoni M, Pastorino F. Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. J Control Release 2010; 145:66-73. Abstract, PDF

Souza GR, Molina JR, Raphael RM, Ozawa MG, Stark DJ, Levin CS, Bronk LF, Ananta JS, Mandelin J, Georgescu MM, Bankson JA, Gelovani JG, Killian TC, Arap W, Pasqualini R. Three-dimensional tissue culture based on magnetic cell levitation. Nat Nanotechnol 2010; 5:291-6. Abstract, PDF

Ozawa MG, Cardó-Vila M, Mintz PJ, Arap W, Pasqualini R. Cracking the code of compartment-specific dual functionality proteins in cancer: CRKL as another example. Cell Cycle 2010; 9:8-9. Abstract, PDF

Ardelt PU, Kneitz B, Adam P, Reiss C, Kocot A, Fensterle J, Chen L, Pasqualini R, Arap W, Gerharz EW, Riedmiller H. Reactive antibodies against bacillus Calmette-Guerin heat shock protein-65 potentially predict the outcome of immunotherapy for high grade transitional cell carcinoma of the bladder. Cancer 2010; 116:600-9.  Abstract, PDF

Weaver MS, Workman G, Cardo-Vila M, Arap W, Pasqualini R, Sage EH. Processing of the matricellular protein Hevin in mouse brain is dependent on ADAMTS4. J Biol Chem Epub. 2009. Abstract, PDF

Dias-Neto E, Nunes DN, Giordano, RJ, Sun J, Botz GH, Yang K, Setubal JC, Pasqualini R, Arap W. Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis. PLoS One 2009; 4:e8338. Abstract, PDF

Trepel M, Stoneham CA, Eleftherohorinou H, Mazarakis ND, Pasqualini R, Arap W, Hajitou A. A herotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. Mol Cancer Ther. 2009; 8:2383-91. Abstract, PDF

Giordano RJ, Edwards JK, Tuder RM, Arap W, Pasqualini R. Combinatorial ligand-directed lung targeting. Proc Am Thorac Soc 2009; 6:411-5.  Abstract, PDF

Stefanidakis M, Karjalainen K, Jaalouk DE, Gahmberg CG, O'Brien S, Pasqualini R, Arap W, Koivunen E. Role of leukemia cell invadosome in extramedullary infiltration. Blood. 2009; 114:3008-17. Abstract, PDF

Jonasch E, Wood CG, Matin SF, Tu SM, Pagliaro LC, Corn PG, Aparicio A, Tamboli P, Millikan RE, Wang X, Araujo JC, Arap W, Tannir N. Phase II presurgical feasibility study of bevacizumab in untreated patients with metastatic renal cell carcinoma. J Clin Oncol. 2009; 27:4076-81. Abstract, PDF

Zhang Y, Daquinag A, Traktuev DO, Amaya-Manzanares F, Simmons PJ, March KL, Pasqualini R, Arap W, Kolonin MG. White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models. Cancer Res. 2009; 69:5259-66. Abstract, PDF

Moeller BJ, Pasqualini R, Arap W. Targeting cancer-specific synthetic lethality in double-strand DNA break repair. Cell Cycle. 2009; 8:1872-6. Abstract, PDF

Paoloni MC, Tandle A, Mazcko C, Hanna E, Kachala S, Leblanc A, Newman S, Vail D, Henry C, Thamm D, Sorenmo K, Hajitou A, Pasqualini R, Arap W, Khanna C, Libutti SK. Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature. PLoS ONE. 2009; 4:e4972. Abstract, PDF

Lewis VO, Ozawa MG, Deavers MT, Wang G, Shintani T, Arap W, Pasqualini R. The interleukin-11 receptor alpha as a candidate ligand-directed target in osteosarcoma: consistent data from cell lines, orthotopic models, and human tumor samples. Cancer Res. 2009; 69:1995-9. Abstract, PDF

Marchiò S, Arap W, Pasqualini R. Targeting the extracellular signature of metastatic colorectal cancers. Expert Opin Ther Targets 2009; 13:363-79. Abstract, PDF

Mandelin J, Lin EC, Hu DD, Knowles SK, Do KA, Wang X, Sage EH, Smith JW, Arap W, Pasqualini R. Extracellular and intracellular mechanisms that mediate the metastatic activity of exogenous osteopontin. Cancer. 2009; 115:1753-64. Abstract, PDF

Staquicini FI, Dias-Neto E, Li J, Snyder EY, Sidman RL, Pasqualini R, Arap W. Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells. Proc Natl Acad Sci U S A. 2009; 106:2903-8. Abstract, PDF

Mintz PJ, Cardó-Vila M, Ozawa MG, Hajitou A, Rangel R, Guzman-Rojas L, Christianson DR, Arap MA, Giordano RJ, Souza GR, Easley J, Salameh A, Oliviero S, Brentani RR, Koivunen E, Arap W, Pasqualini R. An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment. Proc Natl Acad Sci U S A. 2009; 106:2182-7. Abstract, PDF

Moeller BJ, Pasqualini R, Arap W. Ceramide-mediated apoptosis following ionizing radiation in human prostate cancer cells: PKCalpha joins the fray. Cancer Biol Ther. 2009; 8:64-5. Abstract, PDF

Tandle A, Hanna E, Lorang D, Hajitou A, Moya CA, Pasqualini R, Arap W, Adem A, Starker E, Hewitt S, Libutti SK. Tumor vasculature-targeted delivery of tumor necrosis factor-alpha. Cancer. 2009; 115:128-39. Abstract, PDF

Tagore DM, Nolte WM, Neveu JM, Rangel R, Guzman-Rojas L, Pasqualini R, Arap W, Lane WS, Saghatelian A. Peptidase substrates via global peptide profiling. Nat Chem Biol. 2009; 5:23-5. Comment, PDF

Decuzzi P, Pasqualini R, Arap W, Ferrari M. Intravascular delivery of particulate systems: does geometry really matter? Pharm Res. 2009; 26:235-43. Abstract, PDF

Cardó-Vila M, Zurita AJ, Giordano RJ, Sun J, Rangel R, Guzman-Rojas L, Anobom CD, Valente AP, Almeida FCL, Lahdenranta J, Kolonin MG, Arap W, Pasqualini R. A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11. PLoS ONE. 2008; 3:e3452.  AbstractPDF

Giordano RJ, Lahdenranta J, Zhen LJ, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. J Biol Chem. 2008; 283:29447-29460.  AbstractPDF

Staquicini FI, Tandle A, Libutti SK, Sun J, Zigler M, Bar-Eli M, Aliperti F, Perez, EC, Gershenwald JE, Mariano M, Pasqualini R, Arap W, Lopes JD. A subset of host b-lymphocytes control melanoma metastasis through a MCAM/MUC18-dependent interaction: evidence from mice and humans.  Cancer Res. 2008; 68:8419-8428.  AbstractPDF

Nie J, Chang B, Traktuev D, Sun J, March KL, Chan L, Sage EH, Pasqualini R, Arap W, Kolonin MG. Combinatorial Peptides Identify {alpha}5{beta}1 Integrin as a Receptor for the Matricellular Protein SPARC on Adipose Stromal Cells.  Stem Cells. 2008.  AbstractPDF

Corti A, Curnis F, Arap W, Pasqualini R. The neovasculature-homing motif NGR: more than meets the eye.  Blood. 2008.  AbstractPDF

Lin SH, Cheng CJ, Lee YC, Ye X, Tsai WW, Kim J, Pasqualini R, Arap W, Navone NM, Tu SM, Hu M, Yu-Lee LY Logothetis CJ. A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation.  Oncogene. 2008.  AbstractPDF

Ozawa MG, Zurita AJ, Dias-Neto E, Nunes DN, Sidman RL, Gelovani JG, Arap W, Pasqualini R. Beyond Receptor Expression Levels: The Relevance of Target Accessibility in Ligand-directed Pharmacodelivery Systems.  Trends Cardiovasc Med. 2008; 18:126-132.  AbstractPDF

Souza GR, Yonel-Gumruk E, Fan D, Easley J, Rangel R, Guzman-Rojas L, Miller JH, Arap W, Pasqualini R. Bottom-up assembly of hydrogels from bacteriophage and Au nanoparticles: the effect of cis- and trans-acting factors. PLoS ONE. 2008; 21:2242.  AbstractPDF

Nishimura S, Takahashi S, Kamikatahira H, Kuroki Y, Jaalouk DE, O'Brien S, Koivunen E, Arap W, Pasqualini R, Nakayama H, Kuniyasu A. Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells. J Biol Chem. 2008; 283:11752-11762.  AbstractPDF

Hajitou A, Lev DC, Hannay JA, Korchin B, Staquicini FI, Soghomonyan S, Alauddin MM, Benjamin RS, Pollock RE, Gelovani JG, Pasqualini R, Arap W. A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging. Proc Natl Acad Sci USA. 2008.  AbstractPDF

Wood KC, Azarin SM, Arap W, Pasqualini R, Langer R, Hammond PT. Tumor-Targeted Gene Delivery Using Molecularly Engineered Hybrid Polymers Functionalized with a Tumor-Homing Peptide. Bioconjug Chem. 2008.  AbstractPDF

Sato M, Arap W, Pasqualini R. Molecular targets on blood vessels for cancer therapies in clinical trials. Oncology. 2007.  AbstractPDF

Jaalouk DE, Ozawa MG, Sun J, Lahdenranta J, Schlingemann RO, Pasqualini R, Arap W. The Original Pathologische Anatomie Leiden-Endothelium Monoclonal Antibody Recognizes a Vascular Endothelial Growth Factor-Binding Site within Neuropilin-1. Cancer Res. 2007.  AbstractPDFSupplementary Data

Lahdenranta J, Sidman RL, Pasqualini R, Arap W. Treatment of hypoxia-induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease. FASEB J. 2007.  AbstractPDF

Bover LC, Cardó-Vila M, Kuniyasu A, Sun J, Rangel R, Takeya M, Aggarwal BB, Arap WPasqualini R. A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications. J Immunol. 2007; 178:8183-8194.  AbstractPDF

Hajitou A, Rangel R, Trepel M, Soghomonyan S, Gelovani JG, Alauddin MM, Pasqualini R, Arap W. Design and construction of targeted AAVP vectors for mammalian cell transduction. Nat Protoc. 2007; 3: 523-531.  AbstractPDF

Soghomonyan S, Hajitou A, Rangel R, Trepel M, Pasqualini RArap W, Gelovani JG, Alauddin MM. Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU.  Nat Protoc. 2007; 2: 416-423.  AbstractPDF

Rangel R, Sun Y, Guzman-Rojas L, Ozawa MG, Sun J, Giordano RJ, Van Pelt CS, Tinkey PT, Behringer RR, Sidman RL, Arap W, Pasqualini R. Impaired angiogenesis in aminopeptidase N-null mice. Proc Natl Acad Sci U S A. 2007; 14: 4588-4593.  AbstractPDF

Trepel M, Arap W, Pasqualini R. Selection, isolation, and identification of targeting peptides for ligand-directed gene delivery. In: Gene Transfer: A Laboratory Manual, New York: Cold Spring Harbor Laboratory Press. 2007; Ch. 30: 359-369.  PDF

Ji Y, Yin GS, Tsui KW, Kolonin MG, Sun J, Arap W, Pasqualini R, Do KA. Bayesian mixture models for complex high dimensional count data in phage display experiments.  Appl Statist. 2007; 56: 1-14.  PDF

Kzhyshkowska J, Workman G, Cardó-Vila M, Arap W, Pasqualini R, Gratchev A, Krusell L, Goerdt S, Sage EH. Novel function of alternatively activated macrophages: stabilin-1 mediated clearance of SPARC. J Immunol. 2006; 176: 5825-5832.  AbstractPDF

Christianson DR, Ozawa MG, Arap W, Pasqualini R. Techniques to decipher molecular diversity by phage display. Methods Mol Biol. 2006; 357: 385-406.  AbstractPDF

Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I. State of the Art. Cellular and Molecular Mechanisms of Alveolar Destruction in Emphysema: An Evolutionary Perspective. Proc Am Thorac Soc. 2006; 3: 503-510.  AbstractPDF

Souza GR, Levin CS, Hajitou A, Pasqualini R, Arap W, Miller JH. In vivo detection of gold-imidazole self-assembly complexes: NIR-SERS signal reporters. Anal Chem. 2006; 78: 6232-6237.  AbstractPDF

Kolonin MG, Sun J, Do KA, Vidal CI, Ji Y, Baggerly KA, Pasqualini R, Arap W. Synchronous selection of homing peptides for multiple tissues by in vivo phage display. FASEB J. 2006; 20: 979-981.   AbstractPDF

Hajitou A, Trepel M, Lilley CE, Soghomonyan S, Alauddin MM, Marini FC 3rd, Restel BH, Ozawa MG, Moya CA, Rangel R, Sun Y, Zaoui K, Schmidt M, von Kalle C, Weitzman MD, Gelovani JG, Pasqualini R, Arap W. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell. 2006; 125: 385-398.   AbstractPDFNature ReviewsPDF

Yao VJ, Ozawa MG, Varner AS, Kasman IM, Chanthery Y, Pasqualini R, Arap W, McDonald DM. Antiangiogenic therapy decreases integrin expression in normalized tumor blood vessels. Cancer Res. 2006; 66: 2639-2649.   AbstractPDF

Souza GR, Christianson DR, Staquicini FI, Ozawa MG, Snyder EY, Sidman RL, Miller JH, Arap W, Pasqualini R. Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents. Proc Natl Acad Sci  USA. 2006; 103: 1215-1220.   AbstractPDF

Kolonin MG, Bover L, Sun J, Zurita AJ, Do KA, Lahdenranta J, Cardó-Vila M, Giordano RJ, Jaalouk DE, Ozawa MG, Moya CA, Souza GR, Staquicini FI, Kunyiasu A, Scudiero DA, Holbeck SL, Sausville EA, Arap W, Pasqualini R.  Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries. Cancer Res. 2006; 66: 34-40.  AbstractPDF

Giordano RJ, Anobom CD, Cardó-Vila M, Kalil J, Valente AP, Pasqualini R, Almeida FL, Arap W. Structural basis for the interaction of a vascular endothelial growth factor mimic peptide motif and its corresponding receptors. Chem Biol. 2005; 12: 1075-1083.  AbstractPDF

Pentz RD, Cohen CB, Wicclair M, DeVita MA, Flamm AL, Youngner SJ, Hamric AB, McCabe MS, Glover J, Kittiko WJ, Kinlaw K, Keller J, Asch A, Kavanagh JJ, Arap W.  Ethics guidelines for research with the recently dead. Nat Med. 2005; 11: 1145-1149.  AbstractPDF

Lionakis MS, Lahdenranta J, Sun J, Liu W, Lewis RE, Albert ND, Pasqualini R, Arap W, Kontoyiannis DP.  Development of a ligand-directed approach to study the pathogenesis of invasive aspergillosis. Infect Immun. 2005; 73: 7747-7758.  AbstractPDF

Ozawa MG, Yao VJ, Chanthery YH, Troncoso P, Uemura A, Varner AS, Kasman IM, Pasqualini R, Arap W, McDonald DM. Angiogenesis with pericyte abnormalities in a transgenic model of prostate cancer. Cancer. 2005; 104: 2104-2115.  Abstract, PDF

Oh Y, Mohiuddin I, Sun C, Putman JB, Hong WK, Arap W, Pasqualini R. Phenotypic diversity of the lung vasculature in an experimental model of malignant melanoma metastases. Chest. 2005; 128: 596S-600S.  AbstractPDF

Barker TH, Baneyx G, Cardó-Vila M, Workman GA, Weaver M, Menon PM, Dedhar S, Rempel SA, Arap W, Pasqualini R, Vogel V, Sage EH.  SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity.  J Biol Chem. 2005; 280: 36483-36493.  AbstractPDF

Yao VJ, Ozawa MG, Trepel M, Arap W, McDonald DM, Pasqualini R. Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection. Am J Pathol. 2005; 166: 625-636.  AbstractPDF

Marchiò S, Alfano M, Primo L, Gramaglia D, Butini L, Gennero L, De Vivo E, Arap W, Giacca M, Pasqualini R, Bussolino F. Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. Blood. 2005; 105: 2802-2811. Abstract, PDF

Zurita AJ, Troncoso P, Cardó-Vila M, Logothetis CJ, Pasqualini R, Arap W. Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer. Cancer Res. 2004; 64: 435-439.  CoverAbstractPDF

Vidal CI, Mintz PJ, Lu K, Ellis LM, Manenti L, Giavazzi R, Gershenson DM, Broaddus R, Liu J, Arap W, Pasqualini R. An HSP90-mimic peptide revealed by fingerprinting the pool of antibodies from ovarian cancer patients. Oncogene. 2004; 23: 8859-8867.  AbstractPDF

Pasqualini R, Arap W. Hybridoma-free generation of monoclonal antibodies. Proc Natl Acad Sci U S A. 2004; 101: 257-259.  AbstractPDF

Marchiò S, Lahdenranta J, Schlingemann RO, Valdembri D, Wesseling P, Arap MA, Hajitou A, Ozawa MG, Trepel M, Giordano RJ, Nanus DM, Dijkman HB, Oosterwijk E, Sidman RL, Cooper MD, Bussolino F, Pasqualini R, Arap W. Aminopeptidase A is a functional target in angiogenic blood vessels. Cancer Cell. 2004; 5: 151-162.  AbstractPDF

Kolonin MG, Saha PK, Chan L, Pasqualini R, Arap W. Reversal of obesity by targeted ablation of adipose tissue. Nat Med. 2004; 10: 625-632.  AbstractPDFChem & Eng NewsNature News & Views

Chen L, Zurita AJ, Ardelt PU, Giordano RJ, Arap W, Pasqualini R. Design and validation of a bifunctional ligand display system for receptor targeting. Chem Biol. 2004; 11: 1081-1091. AbstractPDF

Arap MA, Lahdenranta J, Hajitou A, Marini FC 3rd, Wood CG, Wright KC, Fueyo J, Arap W, Pasqualini R. Model of unidirectional transluminal gene transfer. Mol Ther. 2004; 9: 305-310. AbstractPDF

Arap W, Pasqualini R. Engineered embryonic endothelial progenitor cells as therapeutic Trojan horses. Cancer Cell. 2004; 5: 406-408.  AbstractPDF

Arap MA, Lahdenranta J, Mintz PJ, Hajitou A, Sarkis AS, Arap W, Pasqualini R. Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands. Cancer Cell. 2004; 6: 275-284.  AbstractPDF

Zurita AJ, Arap W, Pasqualini R. Mapping tumor vascular diversity by screening phage display libraries. J Control Release. 2003; 91: 183-186.  AbstractPDF

Tamm I, Trepel M, Cardó-Vila M, Sun Y, Welsh K, Cabezas E, Swatterthwait A, Arap W, Reed JC, Pasqualini R. Peptides targeting caspase inhibitors. J Biol Chem. 2003; 278: 14401-14405.  AbstractPDF

Sokolov K, Aaron J, Hsu B, Nida D, Gillenwater A, Follen M, MacAulay C, Adler-Storthz K, Korgel B, Descour M, Pasqualini R, Arap W, Lam W, Richards-Kortum R. Optical systems for in vivo molecular imaging of cancer. Technol Cancer Res Treat. 2003; 2: 491-504. AbstractPDF

Pentz RD, Flamm AL, Pasqualini R, Logothetis CJ, Arap W. Revisiting ethical guidelines for research with terminal wean and brain-dead participants. Hastings Cent Rep. 2003; 33: 20-26. AbstractPDF

Müller OJ, Kaul F, Weitzman MD, Pasqualini R, Arap W, Kleinschmidt JA, Trepel M. Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nat Biotechnol. 2003; 21: 1040-1046.  AbstractPDF

Mintz PJ, Kim J, Do KA, Wang X, Zinner RG, Cristofanilli M, Arap MA, Hong WK, Troncoso P, Logothetis CJ, Pasqualini R, Arap W. Fingerprinting the circulating repertoire of antibodies from cancer patients. Nat Biotechnol. 2003; 21: 57-63.  AbstractPDF

Kontoyiannis DP, Pasqualini R, Arap W. Aminopeptidase N inhibitors and SARS.Lancet. 2003; 361: 1558.  AbstractPDF

Ellerby HM, Lee S, Ellerby LM, Chen S, Kiyota T, del Rio G, Sugihara G, Sun Y, Bredesen DE, Arap W, Pasqualini R. An artificially designed pore-forming protein with anti-tumor effects. J Biol Chem. 2003; 278: 35311-35316. CoverAbstractPDF

Cardó-Vila M, Arap W, Pasqualini R. Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V. Mol Cell. 2003; 11: 1151-1162.  AbstractPDF

Ardelt PU, Wood CG, Chen L, Mintz PJ, Moya C, Arap MA, Wright KC, Pasqualini R, Arap W. Targeting urothelium: ex vivo assay standardization and selection of internalizing ligands. J Urol. 2003; 169: 1535-1540.  AbstractPDF

Trepel M, Arap W, Pasqualini R. In vivo phage display and vascular heterogeneity: implications for targeted medicine. Curr Opin Chem Biol. 2002; 6: 399-404.  AbstractPDF

Pasqualini R, Barbas CF 3rd, Arap W. Vessel maneuvers: zinc fingers promote angiogenesis. Nat Med. 2002; 8: 1353-1354.  AbstractPDF

Pasqualini R, Arap W, McDonald DM. Probing the structural and molecular diversity of tumor vasculature. Trends Mol Med. 2002; 8: 563-571.  AbstractPDF

Pasqualini R, Arap W. Translation of vascular diversity into targeted therapeutics. Ann Hematol. 2002; 81 Suppl 2: S66-67.  Abstract

Pasqualini R, Arap W. Profiling the molecular diversity of blood vessels. Cold Spring Harb Symp Quant Biol. 2002; 67: 223-225.  Abstract

Kolonin MG, Pasqualini R, Arap W. Teratogenicity induced by targeting a placental immunoglobulin transporter. Proc Natl Acad Sci U S A. 2002; 99: 13055-13060.  AbstractPDF

Curnis F, Arrigoni G, Sacchi A, Fischetti L, Arap W, Pasqualini R, Corti A. Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells. Cancer Res. 2002; 62: 867-874.  AbstractPDF

Arap W, Kolonin MG, Trepel M, =Lahdenranta J, Cardó-Vila M, Giordano RJ, Mintz PJ, Ardelt PU, Yao VJ, Vidal CI, Chen L, Flamm A, Valtanen H, Weavind LM, Hicks ME, Pollock RE, Botz GH, Bucana CD, Koivunen E, Cahill D, Troncoso P, Baggerly KA, Pentz RD, Do KA, Logothetis CJ, Pasqualini R. Steps toward mapping the human vasculature by phage display. Nat Med. 2002; 8: 121-127.  AbstractPDF

Arap W, Haedicke W, Bernasconi M, Kain R, Rajotte D, Krajewski S, Ellerby HM, Bredesen DE, Pasqualini R, Ruoslahti E. Targeting the prostate for destruction through a vascular address. Proc Natl Acad Sci U S A. 2002; 99: 1527-1531.  AbstractPDF

Greco G, Pal S, Pasqualini R, Schnapp LM. Matrix fibronectin increases HIV stability and infectivity. J Immunol. 2002; 168: 5722-5729.  AbstractPDF

Trepel M, Arap W, Pasqualini R. Modulation of the immune response by systemic targeting of antigens to lymph nodes. Cancer Res. 2001; 61: 8110-8112.  AbstractPDF

Pasqualini R, McDonald DM, Arap W. Vascular targeting and antigen presentation.Nat Immunol. 2001; 2: 567-568.  AbstractPDF

Lahdenranta J, Pasqualini R, Schlingemann RO, Hagedorn M, Stallcup WB, Bucana CD, Sidman RL, Arap W. An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration. Proc Natl Acad Sci U S A. 2001; 98: 10368-10373.  AbstractPDF

Hoffman M, Olson K, Cavender A, Pasqualini R, Gaikwad J, D'Souza R. Gene expression in a pure population of odonoblasts isolated by laser-capture microdissection. J Dent Res. 2001; 80: 1963-1967.  Abstract

Grifman M, Trepel M, Speece P, Gilbert LB, Arap W, Pasqualini R, Weitzman MD. Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids. Mol Ther. 2001; 3: 964-975.  AbstractPDF

Kolonin M, Pasqualini R, Arap W. Molecular addresses in blood vessels as targets for therapy. Curr Opin Chem Biol. 2001; 5: 308-313.  AbstractPDF

Giordano RJ, Cardó-Vila M, Lahdenranta J, Pasqualini R, Arap W. Biopanning and rapid analysis of selective interactive ligands. Nat Med. 2001; 7: 1249-1253.  AbstractPDF

Cardó-Vila M, Arden KC, Cavenee WK, Pasqualini R, Arap W. Is annexin 7 a tumor suppressor gene in prostate cancer? Pharmacogenomics J. 2001; 1: 92-94.  Abstract

Bhagwat SV, Lahdenranta J, Giordano RJ, Arap W, Pasqualini R, Shapiro LH. CD13/APN is activated by angiogenic signals and is essential for capillary tube formation. Blood. 2001; 97: 652-659.  AbstractPDF

Arap W, Pasqualini R. The human vascular mapping project. Selection and utilization of molecules for tumor endothelial targeting. Haemostasis. 2001; 31 Suppl 1: 30-31.  Abstract

Trepel M, Arap W, Pasqualini R. Exploring vascular heterogeneity for gene therapy targeting. Gene Ther. 2000; 7: 2059-2060.  AbstractPDF

Tellier MC, Greco G, Klotman M, Mosoian A, Cara A, Arap W, Ruoslahti E, Pasqualini R, Schnapp LM. Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes. J Immunol. 2000; 164: 3236-3245.  AbstractPDF

Pasqualini R, Koivunen E, Kain R, Lahdenranta J, Sakamoto M, Stryhn A, Ashmun RA, Shapiro LH, Arap W, Ruoslahti E. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 2000; 60: 722-727.  AbstractPDF

Ogawa K, Pasqualini R, Lindberg RA, Kain R, Freeman AL, Pasquale EB. The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization. Oncogene. 2000; 19: 6043-6052.  AbstractPDF

Fukuda MN, Ohyama C, Lowitz K, Matsuo O, Pasqualini R, Ruoslahti E, Fukuda M. A peptide mimic of E-selectin ligand inhibits sialyl Lewis X-dependent lung colonization of tumor cells. Cancer Res. 2000; 60: 450-456.  AbstractPDF

Schneller M, Arap W, Pasqualini R. Immunoblotting of integrins. Methods Mol Biol. 1999; 129: 63-78.  Abstract

Koivunen E, Arap W, Rajotte D, Lahdenranta J, Pasqualini R. Identification of receptor ligands with phage display peptide libraries. J Nucl Med. 1999; 40: 883-888.  Abstract

Koivunen E, Arap W, Valtanen H, Rainisalo A, Medina OP, Heikkila P, Kantor C, Gahmberg CG, Salo T, Konttinen YT, Sorsa T, Ruoslahti E, Pasqualini R. Tumor targeting with a selective gelatinase inhibitor. Nat Biotechnol. 1999; 17: 768-774.  AbstractPDF

Koivunen E, Restel BH, Rajotte D, Lahdenranta J, Hagedorn M, Arap W, Pasqualini R. Integrin-binding peptides derived from phage display libraries. Methods Mol Biol. 1999; 129: 3-17.  Abstract

Ellerby HM, Arap W, Ellerby LM, Kain R, Andrusiak R, Rio GD, Krajewski S, Lombardo CR, Rao R, Ruoslahti E, Bredesen DE, Pasqualini R. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999; 5: 1032-1038. CoverAbstractPDF

Burg MA, Pasqualini R, Arap W, Ruoslahti E, Stallcup WB. NG2 proteoglycan-binding peptides target tumor neovasculature. Cancer Res. 1999; 59: 2869-2874.  AbstractPDF

Arap W, Huang HJ. Expression of integrin transcripts in human cancer cells. Methods Mol Biol. 1999; 129: 91-101.  Abstract 

Invited Articles

Sergeeva A, Kolonin MG, Molldrem JJ, Pasqualini R, Arap W. Display technologies: application for the discovery of drug and gene delivery agents. Adv Drug Deliv Rev. 2006; 58: 1622-1654.  AbstractPDF

Hajitou A, Pasqualini R, Arap W. Vascular targeting: recent advances and therapeutic perspectives. Trends Cardiovasc Med. 2006; 16: 80-88.

Sokolov K, Aaron J, Hsu B, Nida D, Gillenwater A, Follen M, MacAulay C, Adler-Storthz K, Korgel B, Descour M, Pasqualini R, Arap W, Lam W, Richards-Kortum R. Optical systems for in vivo molecular imaging of cancer. Technol Cancer Res. Treat 2003; 2: 491-504. AbstractPDF

Zurita AJ, Arap W, Pasqualini R. Mapping tumor vascular diversity by screening phage display libraries. J Control Release. 2003; 91: 183-186.  AbstractPDF

Pasqualini R, Arap W, McDonald DM. Probing the structural and molecular diversity of tumor vasculature. Trends Mol Med. 2002; 8: 563-571.  AbstractPDF

Pasqualini R, Barbas CF 3rd, Arap W. Putting a Finger on Angiogenesis. Nat Med. 2002.

Pasqualini R, Arap W. Translation of vascular diversity into targeted therapeutics. Ann Hematol. 2002; 81 Suppl 2: S66-67.  Abstract

Trepel M, Pasqualini R, Arap W. In vivo phage display and vascular heterogeneity: implications for targeted medicine. Curr Opin Chem Biol. 2002; 6: 399-404.  AbstractPDF

Kolonin M, Pasqualini R, Arap W. Molecular addresses in blood vessels as targets for therapy. Curr Opin Chem Biol. 2001; 5: 308-313.  AbstractPDF

Arap W, Pasqualini R. The human vascular mapping project. Selection and utilization of molecules for tumor endothelial targeting. Haemostasis. 2001; 31 Suppl 1: 30-31.  Abstract

Koivunen E, Restel BH, Rajotte D, Lahdenranta J, Hagedorn M, Arap W, Pasqualini R. Integrin-binding peptides derived from phage display libraries. Methods Mol Biol. 1999; 129: 3-17.  Abstract

Koivunen E, Arap W, Rajotte D, Lahdenranta J, Pasqualini R. Identification of receptor ligands with phage display peptide libraries. J Nucl Med. 1999; 40: 883-888.  Abstract

Schneller M, Arap W, Pasqualini R. Immunoblotting of integrins. Methods Mol Biol. 1999; 129: 63-78.  Abstract

Arap W, Huang HJ. Expression of integrin transcripts in human cancer cells. Methods Mol Biol. 1999; 129: 91-101.  Abstract

Pasqualini R. Vascular targeting with phage peptide libraries. Q J Nucl Med. 1999; 43: 159-162.  Abstract

Arap W, Pasqualini R, Ruoslahti E. Chemotherapy targeted to tumor vasculature. Curr Opin Oncol. 1998; 10: 560-565.  Abstract

Pasqualini R, Ruoslahti E. Tissue targeting with phage peptide libraries. Mol Psychiatry. 1996; 1: 423.  Abstract

Pasqualini R, Ruoslahti E. Searching for a molecular address in the brain. Mol Psychiatry. 1996; 1: 421-422.  Abstract

Arap W, Huang HJ, Cavenee WK. Cancer genetics and tumor suppression. J Br Assoc Adv Sci. 1994; 46: 18-33.   

Editorials

Arap W, Pasqualini R. Engineered embryonic endothelial progenitor cells as therapeutic Trojan horses. Cancer Cell. 2004; 5: 406-408.  AbstractPDF

Kontoyiannis DP, Pasqualini R, Arap W. Aminopeptidase N inhibitors and SARS. Lancet. 2003; 361: 1558.  AbstractPDF

Pasqualini R, Barbas CF 3rd, Arap W. Vessel maneuvers: zinc fingers promote angiogenesis. Nat Med. 2002; 8: 1353-1354.  AbstractPDF

Pasqualini R, McDonald DM, Arap W. Vascular targeting and antigen presentation. Nat Immunol. 2001; 2: 567-568.  AbstractPDF

Cardó-Vila M, Arden KC, Cavenee WK, Pasqualini R, Arap W. Is annexin 7 a tumor suppressor gene in prostate cancer? Pharmacogenomics J. 2001; 1: 92-94.  Abstract

Trepel M, Arap W, Pasqualini R. Exploring vascular heterogeneity for gene therapy targeting. Gene Ther. 2000; 7: 2059-2060.  AbstractPDF

Book Chapters

Eckhardt BL, Smith TL, Anderson RL, Arap W, Pasqualini R. Stromal‐derived factors that dictate organ-specific metastasis. In: Cancer Metastasis: Biologic Basis and Therapeutics. Cambridge University Press: New York. In Press.

Arap W, Pasqualini R. Combinatorial mapping of vascular zip codes by in vivo phage display. In: Protein Discovery Technologies, Principles, Methods and Applications. Marcel Dekker/CRC Press: Boca Raton, FL, 2009: 99-112.

Driessen WH, Ozawa MG, Arap W, Pasqualini R. Ligand-directed cancer gene therapy to angiogenic vasculature. In: Adv Genet. 67, 2009: 103-21.

Ozawa MG, Staquicini FI, Sidman RL, Pasqualini R, Arap W. Vascular targeting of brain tumors - bridging the gap with phage display. In: CNS Cancer, Cancer Drug Discovery and Development. Ed(s) E.G. Van Meir. Human Press, a part of Springer Science Business Media, LLC, Ch. 32, 2009.

Trepel M, Arap W, Pasqualini R. Selection, isolation, and identification of targeting peptides for ligand-directed gene delivery. In: Gene Transfer, Delivery, and Expression of DNA and RNA: A Laboratory Manual. Ed(s) Friedman and Rossi. Cold Spring Harbor Laboratory Press: New York, 2007: 359-369.

Christianson DR, Ozawa MG, Pasqualini R, Arap W. Techniques to Decipher Molecular Diversity by Phage Display. In: Cardiovascular Proteomics book in Methods in Molecular Biology. 357. Humana Press, 2006: 385-406.

Zurita AJ, Arap W, Pasqualini R. Molecular Characterization of the Endothelium: A Phage Display Perspective. In: Aird WC, eds. Endothelial Biomedicine: A Comprehensive Reference. Cambridge University Press. Description

Lahdenranta J, Arap W, Pasqualini R. The use of proteomics to map phenotypic heterogeneity of the endothelium. In: Aird WC, eds. Endothelial Cell In Health And Disease. Taylor & Francis, 2005: 105-119.

Cardó-Vila M, Vidal CI, Lahdenranta J, Arap W, Pasqualini R. Blood vessels as a target for cancer therapy. In: Syrigos, Harrington, eds. Targeted Therapy for Cancer. (In Press)

Vidal CI, Cardó-Vila M, Lahdenranta J, Arap W, Pasqualini R. Targeting blood vessels in vivo by using phage display libraries. In: Syringos KN, Harrington KJ, eds. Targeted Therapy for Cancer. New York: Oxford University Press Inc, 2003: 250-255.

Kolonin M, Pasqualini R, Arap W. Mapping human vascular heterogeneity by in vivo phage display. In: Hoying JB, eds. Genetics of Angiogenesis. BIOS Scientific Publishers Ltd, Oxford, 2003: 181-187.

Pasqualini R, Arap W. Profiling the molecular diversity of blood vessels. In: Spring Harbor Symposia on Quantitative Biology, 2002; 67: 223-225.

Pasqualini R, Arap W. Vascular Targeting. In: Encyclopedia of Cancer. 2nd ed. Academic Press Inc, New Brunswick, NJ, 2002; 4: 501-507.

Pasqualini R, Arap W. Translation of vascular proteomics into individualized therapeutics. In: Licinio J, Wong ML, eds. Pharmacogenomics: The Search for Individualized Therapies. Wiley-VCH Press, 2002: 525-530.

Pasqualini R, Arap W. Phage displayed peptides as tools to explore vascular heterogeneity. In: Martinez J, Fehrentz JA, eds. Peptides. EPS/Edicion EDK, 2001: 26-30.

Schneller M, Arap W, Pasqualini R. Immunoblotting of integrins. In: Howlett AR, eds. Meth Mol Biol. Humana Press Inc, 1999; 129: 63-78.

Koivunen E, Restel BH, Rajotte D, Lahdenranta J, Hagedorn M, Arap W, Pasqualini R. Integrin-binding peptides derived from phage display libraries. In: Howlett AR, eds. Meth Mol Biol. Humana Press Inc, 1999; 129: 3-17.

Hemler M, Weitzman J, Pasqualini R, Kawaguchi S, Kassner P, Berdichevsky F. Structure, biochemical properties, and biological functions of integrin cytoplasmic domains. In: The integrin: the biological problems. CRC Press Inc, Boca Raton FL, 1994: 1-35.

Hemler M, Bodorova J, Pasqualini R. Adhesion structures: CD29. In: Leukocyte typing V, A.S. 4/72. Oxford University Press, Oxford, 1994.

Brentani RR, Pasqualini R. Receptor purification using the hydropathy complementary approach. In: Receptor Purification. The Humana Press Inc, 1990; 1: 451-457.

Books Edited and Written

Pasqualini R, Arap W. Ed(s) Protein Discovery Technologies, Principles, Methods and Applications. Marcel Dekker/CRC Press: Boca Raton, FL, 2009.

Pasqualini R, Arap W. Ed(s) Tissue-Specific Vascular Endothelial Signals and Vector Targeting, Part A. In: Advances in Genetics. Series Ed(s) T Friedmann, JC Dunlap, SF Goodwin. 67. Academic Press, Elsevier: United Kingdom, 2009.

Manuals and Other Publications

Pasqualini R, Arap W, Rajotte D, Ruoslahti E. In vivo selection of phage-display libraries. In: Barbas CF 3rd, Burton DR, Scott JK, Silverman, GJ, eds. Phage Display: A Laboratory Manual. New York: Cold Spring Harbor Laboratory Press, 2000: 1-24.

Manuscripts Featured in Journal Covers and Captions

Reversal of Obesity

Cover Caption (pdf), PDF, News and Media Releases

Combinatorial Screening in Patients: IL-11 Receptor as a Tumor Target

Featured Cover (pdf), PDF,  News and Media Releases

An Artificially Designed Anti-tumor Protein

Featured Cover (pdf), PDF, News and Media Releases

Molecular Map of the Human Vasculature System

Cover Caption (pdf), PDF, News and Media Releases

Turning on Tumor Apoptosis

Featured Cover, PDF, News and Media Releases


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