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Laboratory Animal Genetic Services

Laboratory Animal Genetic Services provides MD Anderson investigators with cost-effective, customized genetic analysis for research laboratory animal studies. Polymorphic genetic markers are used to support speed congenic development, background strain characterization, genetic quality control and genetic linkage analysis for mice and rats. Consultation on rodent genetics as well as infectious disease PCR testing for laboratory mice and rats is also provided by this core facility.

Services

  • Mouse and rat microsatellite and SNP genotyping supporting marker-assisted backcrossing (Speed Congenic)
  • Genetic background characterization of genetically engineered mouse lines
  • Genetic quality control of inbred strains
  • Mouse and rat cell line authentication
  • Linkage analysis
  • PCR testing for rodent infectious agents including Helicobacter spp., mouse parvovirus (MPV),  rat parvovirus (RPV), mouse hepatitis virus (MHV), mouse norovirus (MNV) and pinworms
  • H2 (MHC) haplotyping
  • PCR sex determination
  • Passenger mutation analysis
  • Rodent genetic consultation (including standard nomenclature)

Director

Fernando Benavides, DVM, PhD, DACLAM
Associate Professor, Molecular Carcinogenesis
Director, Laboratory Animal Genetic Services
Phone: (512) 237-9343
Email: fbenavid@mdanderson.org


© 2014 The University of Texas MD Anderson Cancer Center