Shana L. Palla, M.S.

Principal Statistical Analyst

Degrees

M.S. in Statistics, Kansas State University, Manhattan, KS
B.S. in Mathematics, Kansas State University, Manhattan, KS

Areas of Interest

Clinical protocol design
Data analysis
Statistical support in pediatric oncology

Publications

Rabin KR, Gramatges MM, Borowitz MJ, Palla SL, Shi X, Margolin JF, Zweidler-McKay PA. Absolute lymphocyte counts refine minimal residual disease-based risk stratification in childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2012 [Advance publication online]

Niikura N, Liu J, Hayashi N, Mittendorf E, Gong Y, Palla S, Tokuda Y, Gonzalez-Angulo AM, Hortobagyi G, Ueno N. Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumors. J Clin Oncol 2012 [Advance publication online]

Dev R, Del Fabbro E, Schwartz GG, Hui D, Palla S, Gutierrez N, Bruera E. Preliminary report: Vitamin D deficiency in advanced cancer patients with symptoms of fatigue or anorexia. Oncologist 2011; 16(11):1637-1641.

Hui D, Kilgore K, Nguyen L, Hall S, Fajardo J, Cox-Miller TP, Palla SL, Rhondali W, Kang JH, Kim SH, Del Fabbro E, Zhukovsky DS, Reddy S, Elsayem A, Dalal S, Dev R, Walker P, Yennu S, Reddy A, Bruera E. The accuracy of probabilistic versus temporal clinician prediction of survival for patients with advanced cancer: A preliminary report. Oncologist 2011; 16(11):1642-1648.

Luo C, Zuñiga J, Edison E, Palla S, Dong W, Parker-Thornburg J. Superovulation strategies for 6 commonly used mouse strains. J Am Assoc Lab Anim Sci 2011; 50(4):471-478.

Mori M, Parsons HA, De La Cruz M, Elsayem A, Palla SL, Liu J, Li Z, Palmer L, Bruera E, Fadul NA. Changes in symptoms and inpatient mortality: A study in advanced cancer patients admitted to an acute palliative care unit in a comprehensive cancer center. J Palliat Med 2011; 14(9):1034-1041.

Hui D, Reddy A, Palla S, Bruera E. Neuroleptic prescription pattern for delirium in patients with advanced cancer. J Palliat Care 2011; 27(2):141-147.

Niikura N, Costelloe CM, Madewell JE, Hayashi N, Yu TK, Liu J, Palla SL, Tokuda Y, Theriault RL, Hortobagyi GN, Ueno NT. FDG-PET/CT compared with conventional imaging in the detection of distant metastases of primary breast cancer. Oncologist 2011; 16(8):1111-1119.

Niikura N, Liu J, Costelloe CM, Palla SL, Madewell JE, Hayashi N, Yu TK, Tokuda Y, Theriault RL, Hortobagyi GN, Ueno NT. Initial staging impact of fluorodeoxyglucose positron emission tomography/computed tomography in locally advanced breast cancer. Oncologist 2011; 16(6):772-782.

Dev R, Parsons HA, Palla S, Palmer JL, Del Fabbro E, Bruera E. Undocumented alcoholism and its correlation with tobacco and illegal drug use in advanced cancer patients. Cancer 2011; 117(19):4551-4556.

Niikura N, Liu J, Hayashi N, Palla SL, Tokuda Y, Hortobagyi GN, Ueno NT, Theriault RL. Treatment outcome and prognostic factors for patients with bone-only metastases of breast cancer: a single-institution retrospective analysis. Oncologist 2011; 16(2):155-164.

Dalal S, Palla S, Hui D, Nguyen L, Chacko R, Li Z, Fadul N, Scott C, Thornton V, Coldman B, Amin Y, Bruera E. Association between a name change from palliative to supportive care and the timing of patient referrals at a comprehensive cancer center. Oncologist 2011; 16(1):105-111.

Hui D, Elsayem A, De la Cruz M, Berger A, Zhukovsky DS, Palla S, Evans A, Fadul N, Palmer JL, Bruera E. Availability and integration of palliative care at US cancer centers. JAMA 2010; 303(11):1054-1061.

Hui D, Elsayem A, Palla S, De La Cruz M, Li Z, Yennurajalingam S, Bruera E. Discharge outcomes and survival of patients with advanced cancer admitted to an acute palliative care unit at a comprehensive cancer center. J Palliat Med 2010; 13(1):49-57.

Hui D, Parsons H, Nguyen L, Palla SL, Yennurajalingam S, Kurzrock R, Bruera E. Timing of palliative care referral and symptom burden in phase 1 cancer patients: a retrospective cohort study. Cancer 2010; 116(18):4402-4409.

Parsons HA, de la Cruz MJ, Zhukovsky DS, Hui D, Delgado-Guay MO, Akitoye AE, El Osta B, Palmer L, Palla SL, Bruera E. Characteristics of patients who refuse do-not-resuscitate orders upon admission to an acute palliative care unit in a comprehensive cancer center. Cancer 2010; 116(12):3061-3070.

Robert RS, Ottaviani G, Huh WW, Palla S, Jaffe N. Psychosocial and functional outcomes in long-term survivors of osteosarcoma: a comparison of limb-salvage surgery and amputation. Pediatr Blood Cancer 2010; 54(7):990-999.

Zage PE, Zeng L, Palla S, Fang W, Nilsson MB, Heymach JV, Zweidler-McKay PA. A novel therapeutic combination for neuroblastoma: the vascular endothelial growth factor receptor/epidermal growth factor receptor/rearranged during transfection inhibitor vandetanib with 13-cis-retinoic acid. Cancer 2010; 116(10):2465-2475.

Jiralerspong S, Palla SL, Giordano SH, Meric-Bernstam F, Liedtke C, Barnett CM, Hsu L, Hung M, Hortobagyi GN, Gonzalez-Angulo AM. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J Clin Oncol 2009; 27(20):3297-3302.

Gonzalez-Angulo AM, Stemke-Hale K, Palla SL, Carey M, Agarwal R, Meric-Berstam F, Traina TA, Hudis C, Hortobagyi GN, Gerald WL, Mills GB, Hennessy BT. Androgen receptor levels and association with PIK3CA mutations and prognosis in breast cancer. Clin Cancer Res 2009; 15(7): 2472-2478.

Walker PW, Palla S, Pei BL, Kaur G, Zhang K, Hanohano J, Munsell M, Bruera E. Switching from methadone to a different opioid: what is the equianalgesic dose ratio? J Palliat Med 2008; 11(8):1103-1108.

Wolff JE, Classen CF, Wagner S, Kortmann RD, Palla SL, Pietsch T, Kühl J, Gnekow A, Kramm CM. Subpopulations of malignant gliomas in pediatric patients: analysis of the HIT-GBM database. J Neurooncol 2008; 87(2):155-164.

De Angulo G, Yuen C, Palla SL, Anderson P, Zweidler-McKay P. Absolute lymphocyte count is a novel prognostic indicator in ALL and AML: implications for risk stratification and future studies. Cancer 2008; 112(2):407-415.

Wenzel L, Anderson R, Tucker DC, Palla S, Thomson E, Speechley M, Harrison H, Lewis-Jack O, Fadojutimi-Akinsiku M, Eckfeldt JH, Reiss JA, Rivers CA, Bookman E, Snively BM, McLaren E, Hemochromatosis and Iron Overload Study Research Investigators. Health-related quality of life in a racially diverse population screened for hemochromatosis: results from the Hemochromatosis and Iron Overload Screening (HEIRS) study. Genet Med 2007; 9(10):705-712.

Bedrosian I, Lee C, Tucker SL, Palla SL, Lu K, Keyomarsi K. Cyclin E-associated kinase activity predicts response to platinum-based chemotherapy. Clin Cancer Res 2007; 13(16): 4800-4806.

Curry EA 3rd, Palla S, Hung F, Arbuckle R, Bruera E. Prescribing patterns and purchasing costs of long-acting opioids over nine years at an academic oncology hospital. Am J Health Syst Pharm 2007; 64(15):1619-1625.

Power T, Adams P, Barton J, Acton R, Howe E, Palla S, Walker A, Anderson R, Harrison B, Thomson E. Psychological impact of genetic testing for hemochromatosis (HFE Mutation Analysis) in the HEIRS Study: a comparison of participants recruited in Canada and in the United States. Genet Test 2007; 11(1):55-64.

Petitti DB, Imperatore G, Palla SL, Daniels SR, Dolan LM, Kershnar AK, Marcovina S, Pettitt DJ, Pihoker C. Serum lipids and glucose control: the SEARCH for Diabetes in Youth Study. Arch Petiatr Adolesc Med. 2007; 161:159-65.

Curry EA, Palla S, Hung F, Bruera E, Arbuckle R. Economics of morphine equivalent daily doses (MEDD). Value Health. 2007; 10(3):A172-A172.

De Angulo G, Yuen C, Palla S, Anderson P, Zweidler-McKay P. Absolute lymphoctye count is a novel prognostic indicator in ALL and AML: Implications for risk stratification and future studies. Pediatr Blood Cancer. 2007; 49(4):459-460.

Sabella-River R, Ghisoli M, Levy A, Palla S, De Angulo G, Anderson P, Zweidler-McKay P. Absolute lymphocyte count predicts outcome in pediatric patients with non-Hodgkin. Pediatr Blood Cancer. 2007; 49(4):474.

De Angulo GR, Yuen C, Palla SL, Anderson PM, Zweidler-McKay PA. Absolute lymphocyte count is a novel prognostic indicator in ALL and AML: implications for risk stratification. Pediatr Blood Cancer. 2007; 48(6):605-606.

Levy AG, Sabella-River R, Ghisoli ML, DeAngulo GR, Palla S, Nunez CA, Anderson PM, Zweidler-McKay PA. Absolute lymphocyte count predicts outcome in pediatric patients with non-hodgkin's lymphoma. Pediatr Blood Cancer. 2007; 48(6):618.

Krishnan S, Rana V, Janjan NA, Abbruzzese JL, Gould MS, Das P, Delclos ME, Palla S, Guha S, Varadhachary G, Evans DB, Wolff RA, Crane CH. Prognostic factors in patients with unresectable locally advanced pancreatic adenocarcinoma treated with chemoradiation. Cancer. 2006; 107(11):2589-96.

Bonds DE, Ellis SD, Weeks E, Palla SL, Lichstein P. A practice-centered intervention to increase screening for domestic violence in primary care practices. BMC Fam Pract. 2006; 7:63.

Kershnar AK, Daniels SR, Imperatore G, Palla SL, Pettiti DB, Pettitt DJ, Marcovina S, Dolan LM, Hamman RF, Leise AD, Pihoker C, Rodriguez BL. Lipid abnormalities are prevalent in youth with type I and type II diabetes: the SEARCH for Diabetes in Youth Study. J Pediatr. 2006; 149(3): 314-9.

Rodriquez BL, Palla SL, Fujimoto WY, Liu LL, Mayer-Davis EJ, Kershnar A, Imperatore G, Daniels SR, Williams DE, Linder B, Bell RA, Wadwa RP. Prevalence of cardiovascular disease risk factors in U.S. children and adolescents with diabetes: the SEARCH for diabetes in youth study. Diabetes Care. 2006; 29(8):1891-6.

Kurina S, Konopleva M, Palla SL, Chen W, Kornblau S, Contractor R, Deng X, May WS, Andreeff M, Ruvolo PP. Bcl2 phosphorylation and active PKC alpha are associated with poor survival in AML. Leukemia. 2006; 20(7):1316-9.

Crandall C, Palla S, Reboussin BA, Ursin G, Greendale G. Is there a positive association between mammographic density and bone mineral density? Authors' response. Breast Cancer Res. 2006; 8(2):404.

Crandall C, Palla SL, Reboussin BA, Hu P, Herrington DM, Barrett-Conner E, Reuben DB, Greendale GA. Cross-sectional association between markers of inflammation and serum sex steroid levels in the postmenopausal progestin/estrogen interventions trial. J Womens Health. 2006; 15(1):14-23.

Reuben DB, Palla SL, Hu P, Reboussin BA, Crandall C, Herringon DM, Barrett-Conner E, Greendale GA. Progestins affect mechanism of estrogen-induced C-reactive protein stimulation. Am J Med. 2006; 119(2):167.e1-8.

Hu P, Greendale GA, Palla SL, Reboussin BA, Herrington DM, Barrett-Conner E, Reuben DB. The effects of hormone therapy on the markers of inflammation and endothelial function, and plasma matrix metalloproteinase-9 level in postmenopausal women: the Post-menopausal Estrogen Progestin Intervention (PEPI) Trial. Atheroclerosis. 2006; 185(2):347-52.

Cesari M, Kritchevsky S, Baumgartner R, Atkinson H, Penninx B, Lenchik L, Palla S, Ambrosius W, Tracy R, Pahor M. Sarcopenic obesity and inflammation – Trial on ACE Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. J Clin Nutr. 2005; 82(2):428-34.

Crandall C, Palla S, Reboussin BA, Ursin G, Greendale GA. Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions Study. Breast Cancer Res. 2005; 7(6):R922-8.

Greendale GA, Palla SL, Ursin G, Laughlin GA, Crandall C, Pike MC, Reboussin BA. The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: Results from the postmenopausal estrogen/progestin interventions mammographic density study. Am J Epidemiol. 2005; 162(9):826-834.

Nicklas B, Mychaleckyj J, Kritchevsky S, Palla S, Lange LA, Messier S, Bowden D, Pahor M. Physical function and its response to exercise: associations with cytokine gene variation in older adults with knee osteoarthritis. J Gerontol A Biol Sci Med Sci. 2005; 60(10)1292-8.

Mellen PB, Palla SL, Goff DC Jr, Bonds DE. Prevalence of nutrition and exercise counseling for patients with hypertension. United States, 1999 to 2000. J Gen Intern Med. 2004; 19(9):917-24.

Ursin G, Palla SL, Reboussin BA, Slone S, Wasilauskas C, Pike MC, Greendale GA. Post-treatment change in serum estrone predicts mammographic percent density changes in women who received combination estrogen and progestin in the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. J Clin Oncol. 2004; 22(14):2842-8.

Bonds DE, Palla S, Bertoni AG, Mellen P, Goff DC. Hypertension treatment in the ambulatory setting: comparison by race and gender in a national survey. J Clin Hypertens (Greenwich). 2004; 6(5):223-8; quiz 229-30.

Nicklas BJ, Ambrosius W, Messier SP, Miller GD, Penninx BW, Loeser RF, Palla S, Bleecker E, Pahor M. Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr. 2004; 79(4):544-51.

Bonds DE, Mychaleckyj JC, Watkins R, Palla S, Extrom P. Ambulatory care skills: do residents feel prepared? Med Educ Online [serial online]. 2002; 7:7. http://www.med-ed-online.org

^{Updated February 2, 2012}