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Caimiao Wei, Ph.D.

Principal Statistical Analyst

Degrees

  • Ph.D. in Plant Pathology, Penn State University, University Park, PA
  • M.S. in Statistics, Penn State University, University Park, PA
  • B.S. in Botany, Zhongshan University, Guangzhou, China

Areas of Interest

  • Clinical trial design
  • Survival analysis, generalized linear models, Bayesian statistics
  • Bioinformatics (experimental design and data analysis)

Publications

Prasad S, Yadav VR, Sung B, Reuter S, Kannappan R, Deorukhkar A, Diagaradjane P, Wei C, Baladandayuthapani V, Krishnan S, Guha S, Aggarwal BB. Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine. Clinical Cancer Research 2012; 18(18): 4942-4953.

Lin SH, Komaki R, Liao Z, Wei C, Myles B, Swisher S, Hofstetter W, Ajani J, Cox JD. Proton beam therapy and concurrent chemotherapy for esophageal cancer. International Journal of Radiation Oncology*Biology*Physics 2012; 83(3): e345-351.

Kuhn DJ, Berkova Z, Jones RJ, Woessner R, Bjorklund CC, Ma W, Davis RE, Lin P, Wang H, Madden TL, Wei C, Baladandayuthapani V, Wang M, Thomas SK, Shah JJ, Weber DM, Orlowski RZ. Targeting the insulin-like growth factor-1 receptor to overcome bortezomib resistance in pre-clinical models of multiple myeloma. Blood 2012; 120(16): 3260-3270.

Graybill WS, Frumovitz M, Nick AM, Wei C, Mena GE, Soliman PT, dos Reis R, Schmeler KM, Ramirez PT. Impact of smoking on perioperative pulmonary and upper respiratory complications after laparoscopic gynecologic surgery. Gynecologic Oncology 2012; 125(3): 556-560.

Duong MT, Akli S, Wei C, Wingate HF, Liu W, Lu Y, Yi M, Mills GB, Hunt KK, Keyomarsi K. LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients. PLoS Genetics 2012; 8(3): e1002538.

Amini A, Lin SH, Wei C, Allen P, Cox JD, Komaki R. Accelerated hypofractionated radiation therapy compared to conventionally fractionated radiation therapy for the treatment of inoperable non-small cell lung cancer. Radiation Oncology 2012; 7: 33.

Hess KR, Wei C, Qi Y, Iwamoto T, Symmans WF, Pusztai L. Lack of sufficiently strong informative features limits the potential of gene expression analysis as predictive tool for many clinical classification problems. BMC Bioinformatics 2011; 12: 463.

Bedikian AY, Wei C, Detry M, Kim KB, Papadopoulos NE, Hwu WJ, Homsi J, Davies M, McIntyre S, Hwu P. Predictive factors for the development of brain metastasis in advanced unresectable metastatic melanoma. American Journal of Clinical Oncology 2011; 34(6): 603-610.

Lahat G, Tuvin D, Wei C, Wang WL, Pollock RE, Anaya DA, Bekele BN, Corely L, Lazar AJ, Pisters PW, Lev D. Molecular prognosticators of complex karyotype soft tissue sarcoma outcome: a tissue microarray-based study. Annals of Oncology 2010; 21(5): 1112-1120.

Narvios AB, Mbahi M, Wei C, Lichtiger B. Acceptability of isosulfan blue dye-contaminated blood samples in blood typing and antibody screening laboratory testing in a cancer center. Transfusion 2010; 50(5): 1156.

Wang G, Shao SH, Weng CCY, Wei C, Meistrich ML. Hormonal suppression restores fertility in irradiated mice from both endogenous and donor-derived stem spermatogonia. Toxicological Sciences 2010; 117(1): 225-237.

Nick AM, Schmeler KM, Frumovitz MM, Soliman PT, Spannuth WA, Burzawa JK, Coleman RL, Wei C, dos Reis R, Ramirez PT. Risk of thromboembolic disease in patients undergoing laparoscopic gynecologic surgery. Obstetrics & Gynecology 2010; 116(4): 956-961.

Hess K, Wei C. Learning curves in classification with microarray data. Seminars in Oncology 2010; 37(1):65-68.

Yang WT, Lewis MT, Hess K, Wong H, Tsimelzon A, Karadag N, Cairo M, Wei C, Meric-Bernstam F, Brown P, Arun B, Hortobagyi GN, Sahin A, Chang JC. Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density. Breast Cancer Research and Treatment 2009; 119(2): 305-314.

Narvios A, Mbahi M, Wei C, Lightiger B. Acceptability of lymphazurin-contaminated blood samples for preoperative laboratory testing. Current Issues in Transfusion Medicine 2008; Oct.-Dec.

Bartholomeusz C, Rosen D, Wei C, Kazansky A, Yamasaki F, Takahashi T, Itamochi H, Kondo S, Liu J, Ueno NT. PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival. Cancer Research 2008; 68(22): 9302-9310.

Heller L, Kowalski AM, Wei C, Butler CE. Prospective, randomized, double-blind trial of local anesthetic infusion and intravenous narcotic patient-controlled anesthesia pump for pain management after free TRAM flap breast reconstruction. Plastic and Reconstructive Surgery 2008; 122(4): 1010-1018.

Ren W, Korchin B, Lahat G, Wei C, Bolshakov S, Nguyen T, Merritt W, Dicker A, Lazar A, Sood A, Pollock RE, Lev D.  Combined vascular endothelial growth factor receptor/epidermal growth factor receptor blockade with chemotherapy for treatment of local, uterine, and metastatic soft tissue sarcoma. Clinical Cancer Research 2008; 14(17): 5466-5475.

Ren W, Korchin B, Zhu Q, Wei C, Dicker D, Heymach J, Lazar A, Pollock RE, Lev D. Epidermal growth factor receptor blockade in combination with conventional chemotherapy inhibits soft tissue sarcoma cell growth in vitro and in vivo. Clinical Cancer Research 2008; 14(9): 2785-2795.

Lahat G, Tuvin D, Wei C, Anaya DA, Bekele BN, Lazar AJ, Pisters PW, Lev D, Pollock RE. New perspectives for staging and prognosis in soft tissue sarcoma. Annals of Surgical Oncology 2008; 15: 2739-2748.

Kassouf W, Black PB, Tuziak T, Bondaruk J, Lee S, Brown GA, Adam L, Wei C, Baggerly K, Bar-Eli M, McConkey D, Czerniak B, Dinney CP. Distinctive expression pattern of ErbB family receptors signifies an aggressive variant of bladder cancer. Journal of Urology 2007; 179(1): 353–358.

Oran B, Donato M, Aleman A, Hosing C, Korbling M, Detry MA, Wei C, Anderlini P, Popat U, Shpall E, Giralt S, Champlin RE. Transplant-associated microangiopathy in patients receiving tacrolimus following allogeneic stem-cell transplantation: risk factors and response to treatment. Biology of Blood and Marrow Transplantation 2007; 13(4): 469-477.

Pisters P, Pollock R, Lewis V, Yasko A, Cormier J, Respondek P, Feig B , Hunt K, Lin P, Zagars G,  Wei C,  Ballo M. Long-term results of prospective trial of surgery alone with selective use of radiation for patients with T1 extremity and trunk soft tissue sarcomas. Annals of Surgery 2007; 246(4): 675-681.

Kerr KF, Serikawa KA, Wei C, Peters MA, Bumgarner RE. What is the best reference RNA? And other questions regarding the design and analysis of two-color microarray experiments. OMICS: A Journal of Integrative Biology 2007; 11(2): 152-165.

Anandasabapathy S, Jhamb J, Davila M, Wei C, Morris J, Bresalier R. Clinical and endoscopic factors predict higher pathologic grades of Barrett dysplasia. Cancer 2007; 109(4): 668-674. 

Lev D, Kotilingam D, Wei C, Ballo MT, Zagars GK, Pisters PW, Lazar AA, Patel SR, Benjamin RS, Pollock RE. Optimizing treatment of desmoid tumors. Journal of Clinical Oncology 2007; 25(13): 1785-1791.

Singh B, Berry DA, Shoher A,  Ayers GD, Wei C, Lucci A. COX-2 involvement in breast cancer metastasis to bone. Oncogene 2007; 26(26): 3789-3796.

Wei C, Li JN, Bumgarner RE. Sample size for detecting differentially expressed genes in microarray experiments. BioMed Central (BMC) Genomics 2004; 5(1): 87. 

 

Updated March 7, 2013


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