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Bayesian Biostatistics Conference 2010

Sponsored in part by the Department of Biostatistics at The University of Texas M. D. Anderson Cancer Center

Wednesday, January 27 - Friday, January 29, 2010

M. D. Anderson Cancer Center
Houston, Texas

Program Committee

Donald A. Berry, Ph.D., M. D. Anderson Cancer Center (co-chair)
Telba Z. Irony, Ph.D.
, Center for Devices and Radiological Health, U. S. Food and Drug Administration (co-chair)
Keith A. Baggerly, Ph.D., M. D. Anderson Cancer Center
Kathryn Chaloner, Ph.D., University of Iowa
Stacy R. Lindborg, Ph.D.
, Eli Lilly and Company
Jeffrey S. Morris, Ph.D., M. D. Anderson Cancer Center
Andrew Mugglin, Ph.D., University of Minnesota
Sharon-Lise T. Normand, Ph.D., Harvard Medical School

Preliminary Program

All sessions will be held in the Robert C. Hickey Auditorium, R11.1400
Main Building, Floor 11, M. D. Anderson Cancer Center

Wednesday, January 27 - 7:30 a.m. to 9:00 p.m. 

Short Courses (begin at 8:30 a.m.)

Part I: Bayesian Computation and WinBUGS
Speaker: Gary L. Rosner, Sc.D., Professor of Biostatistics, M. D. Anderson Cancer Center, Houston, TX

Part II: Missing Data
Speaker: Michael J. Daniels, Sc.D., Professor and Chair, Department of Statistics, University of Florida, Gainesville, FL

Part III: Bayesian Computation and WinBUGS
Speaker: Gary L. Rosner, Sc.D., Professor of Biostatistics, M. D. Anderson Cancer Center, Houston, TX

Keynote Address

Why Bother With Bayes?
Thomas A. Louis, Ph.D.

Professor, Department of Biostatistics
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

Case Study I:  I-SPY2, a Biomarker-driven Adaptive Bayesian Phase II Drug-screening Clinical Trial

Speakers: Donald A. Berry, Ph.D., Professor and Head, Division of Quantitative Sciences, M. D. Anderson Cancer Center
Laura Esserman, M.D., Professor of Surgery and Radiology, University of California at San Francisco, San Francisco, CA
Discussants: Paul Gallo, Ph.D., Research Scientist, Novartis Corp, East Hanover, NJ, and Scott S. Emerson, M.D., Ph.D., Professor of Biostatistics, University of Washington, Seattle, WA

Evening Sessions:

Welcome Reception
Poster Session and Discussion

Panel Discussion:

Andrew Mugglin, Ph.D., (Moderator) Research Associate Professor of Biostatistics, University of Minnesota, Minneapolis, MN
Donald A. Berry, Ph.D., Professor and Head, Division of Quantitative Sciences, M. D. Anderson Cancer Center
Scott S. Emerson, M.D., Ph.D., Professor of Biostatistics, School of Public Health, University of Washington, Seattle, WA
Paul Gallo, Ph.D., Research Scientist, Novartis Corp, East Hanover, NJ
Telba Z. Irony, Ph.D., Chief, General & Surgical Devices Branch, CDRH, FDA, Rockville, MD
Thomas A. Louis, Ph.D., Professor of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Sharon-Lise T. Normand, Ph.D., Professor of Biostatistics, School of Public Health, Harvard University, Boston, MA
Barbara C. Tilley, Ph.D., Professor & Director, Division of Biostatistics, School of Public Health, The University of Texas Health Science Center at Houston

Thursday, January 28 - 8:00 a.m. to 5:00 p.m. 

Invited Session I: Bayesian Methods for Observational Data (begins at 9:00 a.m.)

Title: Bayesian Methods, Data Sources and FDRs in the Evaluation of Postmarketing Safety
Speaker: A. Lawrence Gould, Ph.D., Merck Sharp and Dohme Research Laboratories, West Point, PA

Title: Application of Bayesian Concepts in Clinical Decision Making
Speaker:
Roger Lewis, MD, Ph.D., Professor of Medicine, University of California at Los Angeles

Discussant: Karen L. Price, Ph.D., Research Scientist, Eli Lilly and Company, Indianapolis, IN

Invited Session II: Bioinformatics

Title: TBA
Speaker: Giovanni Parmigiani, Ph.D., Professor of Biostatistics, School of Public Health, Harvard University, Boston, MA

Title: TBA
Speaker: Michael A. Newton, Ph.D., Professor of Biostatistics & Medical Informatics, University of Wisconsin-Madison, Madison, WI

Case Study II: Interpreting Trial Results in Light of Conflicting Evidence. A Bayesian Analysis of Adjuvant Chemotherapy for Non--Small-cell Lung Cancer

Speakers: Rebecca Miksad, M.D., M.P.H., Instructor, Department of Medicine, Harvard University, Boston, MA
Mithat Gonen, Ph.D., Associate Attending Biostatistician, Memorial Sloan-Kettering Cancer Center, New York, NY

Discussants: Frank E. Harrell, Jr, Ph.D., Professor and Chair, Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN
Barbara C. Tilley, Ph.D., Professor and Director, Division of Biostatistics, School of Public Health, The University of Texas Health Science Center at Houston

Case Study III: Bayesian Decision Sequential Analysis with Survival Endpoint in Phase II Clinical Trials

Speakers: George G. Woodworth, Ph.D., Professor of Statistics & Actuarial Science, University of Iowa, Iowa City, IA
Lila Zhao, Ph.D., University of Michigan

Discussants: Barbara C. Tilley, Ph.D., Professor and Director, Division of Biostatistics, School of Public Health, The University of Texas Health Science Center at Houston
Frank E. Harrell, Jr, Ph.D., Professor and Chair, Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 

Contributed Session I

Title: Bayesian Adaptive Sequential Item Selection (BASIS): Applying Bayesian Decision Theory to Computerized Adaptive Testing
Speaker: Richard J. Swartz, Ph.D., Instructor, Department of Biostatistics, M. D. Anderson Cancer Center

Title: Semiparametric Bayes Variable Selection for Longitudinal Data
Speaker: Yeonseung Chung, Ph.D., Research Fellow, Department of Biostatisics, Harvard School of Public Health, Boston, MA

Title: Some Semiparametric Bayesian Techniques Useful in Cancer Surveillance
Speaker: Kaushik Gosh, Ph.D., Assistant Professor of Mathematical Sciences, University of Nevada at Las Vegas

Title: Multiplicity-Calibrated Bayesian Hypothesis Tests
Speaker: Mengye Guo, Ph.D., Research Associate, Department of Biostatistics, Harvard School of Public Health and Dana-Farber Cancer Institute, Boston, MA

Title: Adaptive Bayesian Methods for Non-inferiority Tests and Their Implications for Sample Size Calculations
Speaker: Sujit K. Ghosh, Ph.D., Professor of Statistics, North Carolina State University, Raleigh, NC

Friday, January 29 - 7:00 a.m. to 11:15 a.m. 

Contributed Session II (begins at 8:00 a.m.)

Title: A Hierarchical Bayesian Design for Phase I Trials of Novel Combinations of Cancer Therapeutic Agents
Speaker: Thomas M. Braun, Ph.D., Associate Professor of Biostatistics, University of Michigan, Ann Arbor MI

Title: Integrated Two-component Prediction (ITP) Model in Bayesian Biostatistics
Speaker: Haoda Fu, Ph.D., Research Scientist, Eli Lilly and Company, Indianapolis, IN

Title: Control Covariate Imbalance in Clinical Trials with Response-adaptive Randomization
Speaker: Xuelin Huang, Ph.D., Associate Professor of Biostatistics, M. D. Anderson Cancer Center

Title: Principle Stratification for Evaluation of Surrogate Endpoints with Varying Control-group Response
Speaker: Corwin M. Zigler, Ph.D., Graduate Student, Department of Biostatistics, UCLA School of Public Health, Los Angeles, CA

Title: A Comparison of the U.S. and U.K. EQ-5D Health States Valuations Using a Nonparametric Bayesian Method
Speaker: Samer A. Kharroubi, Ph.D., Lecturer, Department of Mathematics, The University of York, Henslington, York, UK

Invited Session III:     Clinical Trials

Title: TBA
Speaker: J. Jack Lee, Ph.D., Professor of Biostatistics, M. D. Anderson Cancer Center

Title: TBA
Speaker: Scott Berry, Ph.D., Berry Consultants, College Station, TX

 

Poster Presentations

All participants are encouraged to display a poster at the conference poster session and discussion. If interested, please send an abstract (up to 300 words) to Lydia Davis via e-mail at lbdavis@mdanderson.org. The deadline to send a poster abstract is December 31, 2009.

The printed poster may have a vertical or horizontal orientation, with dimensions up to a maximum size of 120 cm x 120 cm (48 inches by 48 inches). Push pins and a display board will be provided at the conference.

Registration Fees

All fees are in U.S. dollars.
A late fee of $50 will be assessed for registrations received after Friday, January 8, 2010.

  • Full registration: $300
  • Student registration: $150
  • University of Texas employee registration: $150
  • M. D. Anderson Cancer Center employee registration: $100
  • Fee for guest of registrant to attend the evening reception: $40

Online registration is now available.

Directions

Access directions to M. D. Anderson Cancer Center - Walking or Driving and Parking (type room number R11.1400 as your destination)

Or use the Texas Medical Center map for directions (Select the tab to Browse TMC, then scroll down and select M. D. Anderson Cancer Center Main Building)

Lodging / Hotel Information

Reserve your room before January 5, 2010 in order to take advantage of the special group rate offered at the two nearby hotels listed below. Rates apply for lodging January 26 – 29, 2010; click on the hotel name for online reservations.

Hilton Houston Plaza / Medical Center
6633 Travis Street, Houston TX 77030
Phone: 713-313-4000 (local) / 1-800-445-8667 (outside the Houston area) / if calling from outside the U.S. and Canada, contact the local Hilton reservation office for your region. 
Group code: BBC (Bayesian Biostatistics 2010 Conference)

Houston Marriott Medical Center Hotel
6580 Fannin Street, Houston, TX 77030
Phone: 713-796-0080 (local) / 1-800-228-9290   
Group code: BYBBYBA (Bayesian Biostatistics)

Conference Refund / Substitution / Cancellation

The registration fee, minus a $50 administrative handling fee, is refundable if a written request is received by CME/Conference Management on or before December 27, 2009. If the original registration fee was paid with a company or institutional check, please include the tax ID number of the company or institution on the request for a refund. Identify the 2010 Bayesian Biostatistics Conference. Send the request to CME/Conference Management, Unit 1318, The University of Texas M. D. Anderson Cancer Center, P. O. Box 301439, Houston, TX 77230-1439, U.S.A. 

No refunds will be granted for requests received after December 27, 2009. If unable to attend the conference, a paid registrant may transfer his/her registration to another participant. 

Should the need arise, the Department of Biostatistics reserves the right to make substitutions in speakers or courses offered at the conference. 

The Department of Biostatistics reserves the right to cancel this conference prior to the scheduled date if low enrollment or other circumstances make it necessary. In case of cancellation, liability of the Department of Biostatistics and all sponsoring agents is limited to the registration fee, which will be refunded in full. Registrants will be notified by e-mail, postal mail or the contact number listed on the registration form.

The Department of Biostatistics and all supporting agents reserve the right to limit the number of participants in this program and are not responsible for any expenses incurred by an individual whose registration is not confirmed and for whom space is not available. 

For additional information, contact CME/Conference Management at 713-792-2223 or toll-free at 1-866-849-5866.


© 2009 The University of Texas M. D. Anderson Cancer Center