Selected Publications
Selected Articles
- Vila Ellis L, Chen J. A cell-centric view of lung alveologenesis. Dev Dyn. ePub 11/9, 2020. PMID: 33169483.
- Little DR, Lynch AM, Yan Y, Akiyama H, Kimura S, Chen J. Lung lineage transcription factor NKX2-1 epigenetically resolves opposing cell fates in vivo. bioRxiv.
- Cain MP, Hernandez BJ, Chen J. Quantitative single-cell interactomes in normal and virus-infected mouse lungs. Dis Model Mech. ePub 5/27, 2020. PMID: 32461220.
- Gerner-Mauro KN, Akiyama H, Chen J. Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors. Proc Natl Acad Sci U S A. ePub 5/15, 2020. PMID: 32414917.
- Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J. Epithelial Vegfa specifies a distinct endothelial population in the mouse lung. Dev Cell. 52 (5):617-630.e6, 2020. PMID: 32059772.
- Little DR, Gerner-Mauro KN, Flodby P, Crandall ED, Borok Z, Akiyama H, Kimura S, Ostrin EJ, Chen J. Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1 (cover article). Proc Natl Acad Sci U S A. 116 (41): 20545-20555, 2019. PMID: 29440304.
- Ostrin EJ, Little DR, Gerner-Mauro KN, Sumner EA, Ríos-Corzo R, Ambrosio E, Holt SE, Forcioli-Conti NR, Akiyama H, Hanash SM, Kimura S, Huang SXL, Chen J. Beta-Catenin maintains lung epithelial progenitors after lung specification (cover article). Development 145 (5), 2018. PMID: 29440304.
- Yang J, Hernandez BJ, Martinez Alanis D, Narvaez Del Pilar O, Vila-Ellis L, Akiyama H, Evans SE, Ostrin EJ, Chen J. Development and Plasticity of Alveolar Type 1 Cells (cover article). Development 143 (1) :54-65, 2016. PMID: 26586225.
- Alanis DM, Chang DR, Akiyama H, Krasnow MA, Chen J. Two Nested Developmental Waves Demarcate a Compartment Boundary in the Mouse Lung. Nat Commun 5:3923, 2014. PMID: 24879355.
- Yang J, Chen J. Developmental Programs of Lung Epithelial Progenitors: a Balanced Progenitor Model. Wiley Interdiscip Rev Dev Biol 3 (5) :331-47, 2014. PMID: 25124755.
- Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J. Lung epithelial branching program antagonizes alveolar differentiation (cover article). Proc Natl Acad Sci U S A. 110 (45): 18042-51, 2013. PMID: 24058167.
- Chen J, Krasnow MA. Integrin Beta 1 suppresses multilayering of a simple epithelium. PLoS One 7 (12) :e52886, 2012. PMID: 23285215.
- Chen J, Nathans J. Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse. Invest Ophthalmol Vis Sci 48 (6) :2799-805, 2007. PMID: 17525215.
- Chen J, Nathans J. Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis. Dev Cell 13 (3) :325-37, 2007. PMID: 17765677.
- Chen J, Rattner A, Nathans J. Effects of L1 retrotransposon insertion on transcript processing, localization and accumulation: lessons from the retinal degeneration 7 mouse and implications for the genomic ecology of L1 elements. Hum Mol Genet 15 (13) :2146-56, 2006. PMID: 16723373.
- Chen J, Rattner A, Nathans J. The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes. J Neurosci 25 (1) :118-29, 2005. PMID: 15634773.
Invited Articles
- Chen J. Origin and regulation of a lung repair kit. Nat Cell Biol 19 (8) :885-886, 2017. PMID: 28752852.
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