Krishna Bhat, Ph.D., Principal Investigator
Dr. Bhat obtained his Ph.D. from the University of Illinois at Chicago followed by a post-doctoral training at the MD Anderson Cancer Center. Dr. Bhat has broad expertise in cellular and molecular biology, stem cell biology, pre-clinical models of cancer, and bioinformatics.
He is a recipient of the adult basic science research award from the Society of Neuro-oncology and is credited to have discovered proneural to mesenchymal transition in GBM. He is a curious scientist and an avid collaborator with a primary interest in brain tumors. When not writing grants, Dr. Bhat is a home chef, likes to play basketball with his boys, or catches up on sleep.
Nancy Milam, Lab Manager
Nancy is a biochemist and the lab manager for the Bhat lab. In previous positions, she has done work with NMR, IR spectrometry, GC-MS, X-ray crystallography, and flow cytometry. In the Bhat lab, Nancy is studying immune cell recruitment to tumor sites in CX3CR1 knock-out mice. In her free time, Nancy has adventures around the city with her boyfriend and children, and wrangles their 2 cats, 5 lizards, 4 snakes, and numerous insect colonies at home.
Hiroshi Katayama, Ph.D., Associate Professor
Hiroshi received his Ph.D. in Molecular Biology from Hiroshima University, Japan. He was then trained as a postdoctoral fellow at MD Anderson Cancer Center where he studied the functional interactions of Aurora kinase family. He then joined at the Okayama University School of Medicine, Japan, where he headed the Molecular Oncology Laboratory. In 2021 he returned MD Anderson Cancer Center as an Associate Research Professor. His research interests include studies of breast, pancreatic and brain cancers, with a particular focus on elucidating the molecular mechanisms involved in oncogenic signaling pathways. He is joint appointment in both Drs. Bhat and Sen laboratory.
Pravesh Gupta, Ph.D., Postdoctoral Fellow
Pravesh is an entrepreneurial myeloid cell immunologist currently navigating the immune universe in neuro-oncology. He characterized the fascinating complexity of antigen presenting cells (macrophages and dendritic cells) and their functional elucidation in malaria for his Ph.D. at the Nanyang Technological University, Singapore. This was followed by a short post-doctoral training in understanding immune contexture of transcriptionally stratified hepatocellular carcinoma patients at the Translational Immunology Institute Duke-NUS SingHealth, Singapore. Currently he is exploring the phenotypic and functional diversity of myeloid cells (in particular macrophages) and underlying mechanisms that define immune altering milieu in the GBM tumor microenvironment. Beyond research, Pravesh enjoys travelling, sports, yoga, social work, networking and playing with kids keeps him energetic.
Rakesh Trivedi, Ph.D., Postdoctoral Fellow
Rakesh is a computational biologist currently investigating the underlying regulatory mechanisms of disease progression in different cancer types. His research interest lies in understanding the cancer progression from genomics, transcriptomics, epigenomics and proteomics perspectives by implementing state-of-the-art computational approaches. During his Ph.D. at Centre for DNA Fingerprinting and Diagnostics (India), he had developed an amino acid substitution matrix appropriate for homologs search of eukaryotic proteins enriched with intrinsically disordered regions. In addition to research, he is fond of traveling, photography, musical concerts, writing poems, organizing group events, and long chats with friends over coffee.
Tiffany Tang, Undergraduate Student
Tiffany is an undergraduate at Rice University studying biosciences with a concentration in cell biology and genetics. In the Bhat Lab, she is currently investigating underlying molecular mechanisms that promote GBM radioresistance.
Andrew Gillard, Graduate Student
Andrew is a molecular biologist from South Africa who is currently working towards his PhD in cancer biology and immunology at the University of Texas MD Anderson Graduate School of Biomedical Sciences. During his time in the Bhat laboratory, Andrew is working to understand the role of microglia and the expression of TREM2 in remodeling the tumor microenvironment in GBM. Outside of the lab, Andrew is a keen squash player and enjoys cooking.
Graduate Students: Siobhan Conroy, Arvid Das
UT GSBS Rotation Students: Hannah Savage, Heather Sonneman
Summer Undergraduate Students: Jeremiah Lin, Joel Reyes, Minerva Contreras, Dwayne Bragg
Summer High School Students: Sathwik Iyer, Isha Mondal
Visiting Scientists/Students: Xing Guo, Xiaoming Wu
Technicians: Hetshree Patel, Farah Mukheef