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Non-Hodgkin's Lymphoma

Our Approach

Nathan Fowler, M.D., is focusing his clinical research on finding new therapies that use the body's own immune system to fight non-Hodgkin's lymphoma.

At MD Anderson's Lymphoma and Myeloma Center, one of the nation's most experienced and skilled teams of experts focus their expertise on helping you fight non-Hodgkin's lymphoma. Drawing upon a wide range of treatments for every stage of disease, as well as clinical trials of new and novel agents, physicians design a treatment plan that is uniquely yours.

Our goal is to treat non-Hodgkin's lymphoma with methods that are strong on the disease, but as gentle as possible on your body. We're constantly working to bring new treatments to patients, including targeted biological agents that help your body fight the cancer.

While some patients with non-Hodgkin's lymphoma can be successfully treated, for many the most-effective course is to keep knocking back the disease over a period of many years. In these cases, personalized long-term care is especially important. Our teams of specialized physicians, as well as support staff including nurses, physician assistants, dietitians, social workers and many others, work closely together – and with you – to give you higher chance for successful treatment.

Groundbreaking Research

MD Anderson has helped advance the treatment of non-Hodgkin's lymphoma in many areas, including development of new, leading-edge treatments. Our doctors recently pioneered Rituxan®, a vaccine that helps the body fight lymphoma. And we continue to research ways to improve your health and quality of life.

At MD Anderson's Lymphoma and Myeloma Center, you benefit from one of the most active research programs in the United States, which includes a prestigious federally funded SPORE (Specialized Program of Research Excellence) program. This means we are able to offer a wide range of clinical trials (research studies) for every type and stage of non-Hodgkin's lymphoma.

If you have been diagnosed with non-Hodgkin's lymphoma or have been fighting it for a while, we're here to help. Call 1-877-632-6789 to make an appointment or request an appointment online.

Why Choose MD Anderson?

  • Customized non-Hodgkin’s lymphoma treatments include vaccine and cytokine therapies, monoclonal antibodies, liposomal drug delivery and proton therapy
  • Advanced therapies that deliver maximum effects with the least impact on your body
  • Specialized team approach to long-term care
  • One of nation’s most active lymphoma programs
  • Renowned research program with numerous lymphoma clinical trials

Non-Hodgkins Lymphoma Knowledge Center

Treatment at MD Anderson

Non-Hodgkin's lymphomas are treated in our:

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Bill Crews

"You get top-notch treatment here. You're not just a number. You're a person, and they want to see you survive."

Non-Hodgkin's Lymphoma Survivor Bill Crews

Non-Hodgkin’s Lymphoma Facts

Non-Hodgkin’s lymphoma is the seventh most common cancer in men and women in the nation. According to the American Cancer Society, about 66,000 new cases of non-Hodgkin’s lymphoma are diagnosed each year in the United States. Non-Hodgkin’s lymphoma is slightly more common in white men.

Lymphoma is a general term for cancers that develop in the lymphatic system (the tissues and organs that produce, store and carry white blood cells). Hodgkin’s disease is a type of lymphoma that develops in white blood cells.

Lymphomas that do not start in white blood cells are called non-Hodgkin’s lymphoma. They may start in the bone marrow, spleen, thymus or lymph nodes and spread to other parts of the body.

The lymph system carries disease-fighting white blood cells throughout the body. It includes:

Lymph: Fluid that carries lymphocytes, a type of white blood cells, through the body in a network of lymph vessels, which are like tiny veins. Lymph helps fight against infection and cancer.

Lymph nodes: Tiny, bean-shaped masses in the underarm, pelvis, neck, abdomen and groin. They filter lymph and store white blood cells to help the body fight disease.

Spleen: An organ on the left side of the abdomen that makes lymphocytes, stores blood cells and gets rid of old blood cells.

Thymus: Located in the chest, this tiny organ stores lymphocytes.

Tonsils: Nodes in back of throat that produce lymphocytes.

Bone marrow: Material in bones that produces blood cells.

Non-Hodgkin's Lymphoma Types

Non-Hodgkin’s lymphoma is divided into three types depending on the type of cells in the cancer. These types are:

  • B-cell, which makes up 85% of Non-Hodgkin’s lymphoma cases
  • T-cell
  • NK-cell

Non-Hodgkin’s lymphoma is classified also by how quickly it spreads.

Low-grade non-Hodgkin’s lymphoma includes:

  • Marginal zone lymphoma
  • Mucosa-associated lymphoid tissue (MALT) lymphoma
  • Follicular lymphoma
  • Mantle cell lymphoma

Intermediate grade non-Hodgkin’s lymphoma includes:

  • Diffuse large cell lymphoma
  • Primary mediastinal large cell lymphoma
  • Anaplastic large cell lymphoma

High-grade non-Hodgkin’s lymphoma includes:

  • Burkitt’s lymphoma
  • Lymphoblastic lymphoma

Relapsed non-Hodgkin’s lymphoma is disease that comes back after you have been treated for Non-Hodgkin’s lymphoma.

Refractory non-Hodgkin’s lymphoma is new or relapsed disease that does not respond to treatment.

If you have been diagnosed with non-Hodgkin's lymphoma, we’re here to help. Call 1-877-632-6789 to make an appointment or request an appointment online.


© 2014 The University of Texas MD Anderson Cancer Center