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Hodgkin's Lymphoma

Our Approach

MD Anderson's  Lymphoma and Myeloma Center is known around the world for groundbreaking developments in the treatment of Hodgkin's lymphoma. In fact, our team of experts is one of the few focused only on lymphoma. While most oncologists see only one or two Hodgkin's lymphoma patients a year, we treat hundreds annually, giving us a remarkable depth of experience and expertise.

At MD Anderson, you are cared for by a team of some of the nation's top authorities on lymphoma. They draw upon the latest and most-advanced treatments for all stages of Hodgkin's lymphoma, examining you carefully to determine the best approach and communicating every step of the way.  

Innovative, Advanced Options

As one of the world's leaders in lymphoma advances, we constantly work to pioneer new treatments that are effective and have the least impact on your body. For instance, MD Anderson has helped advance the development of several new targeted therapies for Hodgkin's lymphoma. And we are studying several biomarkers to guide the future development of even more personalized therapies.

Whether you recently have been diagnosed with Hodgkin's lymphoma or have battled the disease for years, we can help. Call 1-877-632-6789 to make an appointment or request an appointment online.

Why Choose MD Anderson?

  • Innovative Hodgkin's lymphoma treatments, including proton therapy, monoclonal antibodies, biological and targeted therapies, stem cell transplants
  • Latest, most-advanced Hodgkin’s lymphoma therapies with highest success rate and least damage to healthy tissue
  • Accurate, precise diagnosis by specialized pathologists
  • One of world’s largest Hodgkin’s lymphoma referral centers
  • Clinical trials for newly diagnosed and relapsed Hodgkin’s lymphoma

Hodgkins Lymphoma Knowledge Center

Treatment at MD Anderson

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Dewayne Hickman

"I'd never wish cancer on anybody, but if anybody has it, I would recommend MD Anderson wholeheartedly."

Hodgkin's Lymphoma Survivor DeWayne Hickman

Hodgkin’s Lymphoma Facts

According to the American Cancer Society, more than 8,500 people are diagnosed with Hodgkin’s lymphoma in the United States each year. It occurs mainly in people:

  • Between 16 and 34 years of age
  • Over age 55

Most patients with Hodgkin’s lymphoma, even in advanced stages, can be treated successfully. However, treatment may cause late side effects, and sometimes the disease returns.

Lymphoma is a general term for cancers that develop in the lymph system, which is part of the body’s immune system. Hodgkin’s lymphoma is a type of lymphoma that develops in the white blood cells. It is different from other lymphomas because it contains Reed-Sternberg cells, a specific type of large cancer cells. While Hodgkin’s lymphoma can start in the lymph nodes, it can spread to almost any organ or tissue, including the liver, bone marrow and spleen.

Hodgkin’s Lymphoma Types

Hodgkin’s lymphoma is divided into two major types, as well as subtypes, according to how the lymph cells look under a microscope and how many Reed-Sternberg cells are present. Knowing the type of lymphoma helps doctors determine your best treatment.

Classical Hodgkin’s lymphoma is the most common type in the United States. It accounts for about 95% of cases and is the most curable Hodgkin’s lymphoma. Subtypes include:

Nodular sclerosing Hodgkin’s lymphoma: The affected lymph nodes have mixed areas of normal cells, Reed-Sternberg cells and prominent scar tissue. This is the most common type, making up 60% to 80% of cases. It is more common in adolescents and young adults, but it can occur at any age.

Lymphocyte-rich classical Hodgkin’s lymphoma: This recently created subtype in the past was confused sometimes with lymphocyte-predominant lymphoma. It is similar to mixed cellularity Hodgkin’s lymphoma.

Mixed cellularity Hodgkin’s lymphoma: The affected lymph nodes contain many Reed-Sternberg cells in addition to several other cell types. Mixed cellularity accounts for about 25% to 30% of cases of Hodgkin’s lymphoma. It primarily affects older adults.

Lymphocyte depletion Hodgkin’s lymphoma: Large numbers of Reed-Sternberg cells, but very few other cell types, are found in the lymph nodes. This is the least common form of Hodgkin's lymphoma, and it is seen more often in people who are elderly or have AIDS.

Lymphocyte-predominant Hodgkin’s lymphoma, also called nodular lymphocyte-predominant Hodgkin’s lymphoma, this rare lymphoma is:

  • Usually diagnosed at an early stage with an excellent prognosis
  • More common among men between 35 and 40

If you have been diagnosed with Hodgkin's lymphoma, we’re here to help. Call 1-877-632-6789 to make an appointment or request an appointment online.


© 2014 The University of Texas MD Anderson Cancer Center