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Ewing's Sarcoma

Our Approach

At MD Anderson's Children's Cancer Hospital, each child with Ewing's sarcoma has a team of highly specialized experts who customize your child's treatment to ensure the most effective therapy with the least impact on the body – now and in the future.

Ewing's sarcoma is rare, and many doctors have little experience with treating it. Our physicians are among the world's most highly trained and experienced in treating Ewing's. This can translate into a better outcome in many cases.

Diagnosis and Treatment

Accurate diagnosis of Ewing's sarcoma can be challenging, but it is essential to successful treatment. Our pathologists are dedicated to sarcoma, and they use the latest, most-sophisticated tests to pinpoint the type and extent of the cancer.

Ewing's sarcoma often requires a multi-therapy approach. Using the latest advances in complex limb-sparing surgeries, our surgeons are often able to avoid amputation if the cancer is in an arm or leg. If amputation is needed, we offer specialized rehabilitation.

Advancing Research

Many children with Ewing's sarcoma are treated with clinical trials. We participate in trials of the Children's Oncology Group and offer other innovative therapies available at only a few hospitals in the nation. Our researchers have helped make many advances, including using drug combinations to treat Ewing's sarcoma.

Our Osteosarcoma and Ewing's Sarcoma Center coordinates care and streamlines and speeds access to clinical trials. In addition, sarcoma researchers work with physicians to translate laboratory research into new clinical trials, which are especially beneficial for patients with relapsed or refractory sarcoma.

Comprehensive Care

Children's Cancer Hospital is designed just for children, with a full range of services and amenities that help make the child and family's experience as comfortable as possible. We go beyond medical care to deliver a comprehensive experience that treats the whole child.

And at Children's Cancer Hospital, you're surrounded by the strength of one of the nation's top cancer centers.

If your child has been diagnosed with Ewing's sarcoma, we're here to help. Call 1-877-632-6789 to make an appointment or request an appointment online.

Why Choose MD Anderson?

  • Extensive expertise in pediatric Ewing's sarcoma
  • Latest diagnostic tools, specialized pathologists
  • Advanced sarcoma surgical procedures, including limb-sparing surgery
  • Most advanced chemotherapy agents and delivery methods
  • Clinical trials of new sarcoma therapies
  • Family-centered care, including comprehensive support services

Ewing's Sarcoma Knowledge Center

Treatment at MD Anderson

Childhood Ewing's sarcoma is treated in our: 

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Jacob Ralston

"We credit proton therapy at MD Anderson for helping to save our son’s life and hope to help others." –Jacob's mom, Susan Ralston

Ewing's Sarcoma Survivor Jacob Ralston

Ewing's Sarcoma Facts

Ewing's sarcomas, or Ewing's tumors, are a category of cancers that form in the bones or soft tissues. According to the American Cancer Society, about 225 children and teens are diagnosed annually with the disease in North America. They account for about 1 percent of pediatric cancers.

Ewing's sarcomas usually form in the pelvis (hip bones), chest (ribs or shoulder blades) or legs, particularly the long bones. Rarely, tumors grow in the skull or flat bones of the trunk.

Researchers have found that Ewing's sarcomas are caused by genetic changes that happen after birth. However, it is not known why some people develop the disease. It is not passed down in families.

About two-thirds of Ewing's sarcoma patients become long-term survivors of the disease.

Ewing's Sarcoma Types

Ewing's sarcomas are categorized into three types. While each type is slightly different, they all are caused by the same gene abnormalities and are treated in the same way.

Ewing's sarcoma of the bone: This is the most common type of Ewing's sarcoma.

Extraosseous Ewing tumor (EOE): These tumors form in soft tissues around bones.

Peripheral primitive neuroectodermal tumor (PPNET): An extremely rare type of cancer, these tumors share certain characteristics with Ewing's sarcoma of the bone and EOE.

If your child has been diagnosed with Ewing's sarcoma, we're here to help. Call 1-877-632-6789 to make an appointment or request an appointment online.

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