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The Brief Fatigue Inventory (BFI)

ORDER ASSESSMENT TOOLS

  

The Brief Fatigue Inventory (BFI) is used to rapidly assess the severity and impact of cancer-related fatigue. An increasing focus on cancer-related fatigue emphasized the need for sensitive tools to assess this most frequently reported symptom. The six inventory items correlate with standard quality-of-life measures.

BFI Features

  • Purpose: To assess the severity of fatigue and the impact of fatigue on daily functioning
  • Population: Patients with fatigue due to cancer and cancer treatment
  • Assessment Areas: Severity of fatigue and the impact of fatigue on daily functioning in the past 24 hours
  • Method: Self-report, interview with research staff, or interactive voice response system (IVR)
  • Time required: Five minutes
  • Scoring: A global fatigue score can be obtained by averaging all the items on the BFI
  • Reliability: Cronbach alpha reliability ranges from 0.82 to 0.97

BFI Language Versions

The BFI is available in the following languages. The BFI may not be modified or translated into another language without the express written consent of the copyright administrator (see Notice of Copyright below).  

Click on a linked language to view a sample in PDF format.

Psychometrically and Linguistically ValidatedLinguistically
Validated
Chinese (Simplified)Afrikaans
Chinese (Traditional)Arabic
EnglishBengali
FilipinoBulgarian
GermanCroatian
GreekCzech
JapaneseDanish
KoreanDutch
Russian French
 Gujarati
 Hebrew
 Hindi
 Hungarian
 Italian
 Latvian
 Malay
 Marathi
 Norwegian
 Polish
 Portuguese (Brazil)
 Slovak
 Spanish
 Tamil
 Telegu
 Thai
 Ukrainian
 Urdu
 

Future Validation Studies: We would like to collaborate with investigators from other countries to develop and validate other language versions of the BFI. Contact us for more information.

To Order the BFI

To use the BFI in a publication or clinical or research trial, you must obtain permission and you must agree to comply with the copyright. Fees may apply (see below).

  • To obtain permission, fill out our order form. The BFI will be e-mailed to you as a PDF file within seven to 10 business days. If your request is urgent, please contact us via e-mail or at the address/phone number below to make special arrangements.
The Department of Symptom Research
Attn: Assessment Tools
The University of Texas MD Anderson Cancer Center
1515 Holcombe Boulevard, Unit 1450
Houston, Texas 77030
713-745-3805
  • The fee structure is as follows:
    • Non-funded academic research and individual clinical practice
      • free of charge
    • Funded academic research
      • $300 per project for the first language version
      • $150 per each additional language version within a project
    • Commercial research
      • $2,000 per project for the first language version
      • $1,200 per each additional language version within a project

If applicable, an invoice will be e-mailed to you within 10 days. Please reference the invoice number on your payment. Include on the memo line, "MD Anderson Assessment Tool Distribution."

Notice of Copyright

The Brief Fatigue Inventory (BFI) copyright is held by The University of Texas MD Anderson Cancer Center and administered by Charles S. Cleeland, PhD. The copyright applies to the BFI and all its derivatives in any language. 

The BFI may not be used or reproduced without permission from the copyright administrator or his designee. Fees for use may apply (see above).

The BFI may not be modified or translated into another language without the express written consent of the copyright administrator. Failure to comply may result in legal action. Contact us via e-mail or at the address shown above to obtain permission to alter or translate the instrument.

Selected References

Validation 

Mendoza T, Wang XS, Cleeland CS, Morrissey M, Johnson BA, Wendt JK, Huber SL. The rapid assessment of fatigue severity in cancer patients: use of the Brief Fatigue Inventory. Cancer 85: 1186-1196, 1999.

Mendoza TR, Laudico AV, Wang XS, Guo H, Matsuda ML, Yosuico VD, Fragante EP, Cleeland CS. Assessment of fatigue in cancer patients and community dwellers: validation study of the Filipino version of the Brief Fatigue Inventory. Oncology 79(1-2): 112-117, 2010.

Mystakidou K, Tsilika E, Parpa E, Mendoza TR, Pistevou-Gombaki K, Vlahos L, Cleeland CS. Psychometric properties of the Brief Fatigue Inventory in Greek patients with advanced cancer. J Pain Symptom Manage 36(4): 367-373, 2008.

Lin CC, Chang AP, Chen ML, Cleeland CS, Mendoza TR, Wang XS. Validation of the Taiwanese Version of the Brief Fatigue Inventory. J Pain Symptom Manage 32(1): 52-59, 2006.

Yun YH, Wang XS, Lee JS, Roh JW, Lee CG, Lee WS, Lee KS, Bang SM, Mendoza TR, Cleeland CS. Validation study of the Korean version of the Brief Fatigue Inventory. J Pain Symptom Manage 29(2): 165-172, 2005.

Wang XS, Hao XS, Wang Y, Guo H, Jiang YQ, Mendoza TR, Cleeland CS. Validation study of the Chinese version of the Brief Fatigue Inventory (BFI-C). J Pain Symptom Manage 27(4): 322-332, 2004.

Okuyama T, Wang XS, Akechi T, Mendoza TR, Hosaka T, Cleeland CS, Uchitomi Y. Validation study of the Japanese version of the Brief Fatigue Inventory. J Pain Symptom Manage 25(2): 106-117, 2003.

Radbruch L, Sabatowski R, Elsner F, Everts J, Mendoza T, Cleeland C. Validation of the German version of the Brief Fatigue Inventory. J Pain Symptom Manage 25(5): 449-458, 2003.

Ionova TI, Novik AA, Manikhas GV, Wang XS, Mendoza TR, Kalyadina SA, Ivanova MO, Uspenskaya OS, Kishtovich AV, Cleeland CS. Validation of Russian versions of Brief Pain Inventory (BPI-R), Brief Fatigue Inventory (BFI-R) and M. D. Anderson Symptom Inventory (MDASI-R) to assess symptoms in cancer patients [abstract]. International Society for Quality of Life Research 10th Annual Conference, Prague, Czech Republic, Nov 12-15, 2003. Qual Life Res 12(7): 798, 2003; 1561.

Valenzuela JO, Gning I, Irarrazaval ME, Fasce G, Marin L, Mendoza TR, Palos G, Reynolds R, Wang XS, Cleeland CS. Psychometric validation of the Spanish version of the Brief Fatigue Inventory [abstract]. The University of Texas MD Anderson Cancer Center, Division of Internal Medicine Research Retreat, Houston TX, May 24, 2012, 2012.

 

Clinical Application

Escalante CP, Meyers C, Reuben JM, Wang X, Qiao W, Manzullo E, Alvarez RH, Morrow PK, Gonzalez-Angulo AM, Wang XS, Mendoza T, Liu W, Holmes H, Hwang J, Pisters K, Overman M, Cleeland C. A randomized, double-blind, 2-period, placebo-controlled crossover trial of a sustained-release methylphenidate in the treatment of fatigue in cancer patients. Cancer J 20(1): 8-14, 1/2014.

Sternberg CN, Molina A, North S, Mainwaring P, Fizazi K, Hao Y, Rothman M, Gagnon DD, Kheoh T, Haqq CM, Cleeland C, de Bono JS, Scher HI. Effect of abiraterone acetate on fatigue in patients with metastatic castration-resistant prostate cancer after docetaxel chemotherapy. Ann Oncol 24(4): 1017-1025, 4/2013.

Shelton ML, Lee JQ, Morris GS, Massey PR, Kendall DG, Munsell MF, Anderson KO, Simmonds MJ, Giralt SA. A randomized control trial of a supervised versus a self-directed exercise program for allogeneic stem cell transplant patients. Psychooncology 18(4): 353-359, 2009.

Park HC, Janjan NA, Mendoza TR, Lin EH, Vadhan-Raj S, Hundal M, Zhang Y, Delclos ME, Crane CH, Das P, Wang XS, Cleeland CS, Krishnan S. Temporal patterns of fatigue predict pathologic response in patients treated with preoperative chemoradiation therapy for rectal cancer. Int J Radiat Oncol Biol Phys 75(3): 775-781, 11/2009.

Yun YH, Lee MK, Chun HN, Lee YM, Park SM, Mendoza TR, Wang XS, Cleeland CS. Fatigue in the general Korean population: application and normative data of the Brief Fatigue Inventory. J Pain Symptom Manage 36(3): 259-267, 2008.

Chang YJ, Lee JS, Lee CG, Lee WS, Lee KS, Bang SM, Wang XS, Mendoza TR, Cleeland CS, Yun YH. Assessment of clinical relevant fatigue level in cancer. Support Care Cancer 15(7): 891-896, 2007.

Anderson KO, Getto CJ, Mendoza TR, Palmer SN, Wang XS, Reyes-Gibby CC, Cleeland CS. Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adults. J Pain Symptom Manage 25(4): 307-318, 2003.

Wang XS, Janjan NA, Guo H, Johnson BA, Engstrom MC, Crane CH, Mendoza TR, Cleeland CS. Fatigue during preoperative chemoradiation for resectable rectal cancer. Cancer 92(6 Suppl): 1725-1732, 2001.

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© 2014 The University of Texas MD Anderson Cancer Center