Promising target improves antitumor response in preclinical models of pancreatic cancer
Mitochondrial enzyme GFER is a key component in creating an immunosuppressive environment in pancreatic cancer
Inhibiting GFER along with immune checkpoint blockade improves antitumor response in preclinical models
Inhibiting GFER along with immune checkpoint blockade improves antitumor response in preclinical models
Researchers at The University of Texas MD Anderson Cancer Center have found that a mitochondrial enzyme, GFER, creates an immunosuppressive environment within pancreatic tumors, leading to treatment resistance.
<...
Researchers identify target to overcome treatment resistance in preclinical models of KRAS-mutant cancers
Researchers identified that RASH3D19 creates a positive feedback loop that drives hyperactivity of RAS signaling and leads to tumor growth and...
Study provides comprehensive insights into DNA language models
Researchers examined five AI models on multiple genomic tasks to see how well they performed
Models performed well overall, with each having...