Blood biomarker points to increased risk of brain metastasis in patients with inflammatory breast cancer
Brain metastases are a common complication of inflammatory breast cancer
High levels of soluble E-cadherin in the blood are associated with increased brain metastasis in these patients
A CXCR2 inhibitor reduced metastasis and improved survival in preclinical models, suggesting that targeting this pathway could prevent or treat brain metastasis
Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable...
Researchers identify novel therapeutic target to improve recovery after nerve injury
Peripheral nerve injury reduces the ability of macrophages to clear dead or dying cells – a process known as efferocytosis – leading to chronic...
High levels of protein drive tumor immune suppression in head and neck cancer
BATF2 is a new type of tumor suppressor that can be epigenetically silenced by high levels of glutamine in the tumor microenvironment
Glutamine...
Circadian rhythms may affect risk of bacterial infection
Researchers identified an inflammation biomarker in laboratory model that predicts which individuals are at an increased risk of bacterial infection
Maternal circardian rhythms influence how often offspring have high levels of baseline inflammation biomarkers, increasing susceptibility to bacterial infections
Interfering with circadian genes eliminated this, suggesting that changes in circadian timing can lead to non-genetic and non-environmental...
