Study shows strong evidence for effectiveness of metastasis-directed radiation therapy in prostate cancer
Metastasis-directed therapy (MDT) significantly improved progression-free survival and later endpoints
Data indicate statistically significant benefits from the addition of MDT to standard of care across multiple disease states
This individual patient meta-analysis from multiple international studies offers the highest-level evidence to date supporting the benefits of MDT
Metastasis-directed therapy (MDT) significantly improved outcomes...
Study reveals synergistic effect of CDK2 and CDK4/6 combination therapy
This preclinical study explains the mechanism underlying CDK2 and CDK4/6 combination therapy, providing a blueprint for future clinical use...
Engineered nanobodies improved respiratory defenses in preclinical study
There are no current therapies designed to improve protection against multiple different respiratory viruses
Engineered nanobodies improved...
Novel immunotherapy demonstrates early potential to overcome resistance to immune checkpoint therapy
Linavonkibart, also known as SRK-181, is an experimental therapy from Scholar Rock that aims to prevent or overcome resistance to immune checkpoint therapies like pembrolizumab
In this trial, objective responses were seen in multiple tumor types despite a heavily pretreated patient population
These findings warrant continued exploration of linavonkibart in earlier lines of therapy
According to a Phase I study led by researchers...