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Study #2017-0418

A Phase 1 Study of the TRK Inhibitor Selitrectinib (BAY 2731954) in Adult and Pediatric Subjects with Previously Treated NTRK Fusion Cancers

MD Anderson Study Status

Not Accepting

Treatment Agent

Selitrectinib (BAY2731954)


Description

This research study is done to test the safety of the new drug selitrectinib in children and adults with cancer having a change in a particular gene (NTRK1, NTRK2 or NTRK3). The drug may treat cancer by interfering with the effect of the NTRK genes on cancer growth. The study also investigates how the drug is absorbed and processed in the human body, and how well and for how long the cancer responds to the drug. This is the first study to test selitrectinib in humans with cancer, for whom no other effective therapy exists.


Resources and Links

Phone Number: 1-877-MDA-6789

clinicaltrials.gov NCT No: NCT03215511 Opens a new window

Information and next steps

Disease:

Solid Tumors Harboring NTRK Fusion

Study phase:

Phase I

Physician name:

David Sanghyun Hong

Department:

Investigational Cancer Therapeutics

For general questions about clinical trials:

1-877-632-6789

Ask a Question

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