The T. C. Hsu Molecular Cytogenetics Facility (MCF) is funded by the Center for Genetics and Genomics (CGG). Guillermina Lozano, Ph.D. is the Director and Asha S. Multani, Ph.D. is the Co-Director of the facility. The MCF is administered through theDepartment of Genetics.
This facility offers conventional as well as molecular cytogenetic services including cell line authentication, species identification, karyotyping, analysis of genomic instability, fluorescence in situ hybridization and Spectral Karyotyping.
One of the key expertise of our facility is to validate the origin of cell lines. Approximately 20-30% of all cell lines used in biomedical research are contaminated. Many top tier journals have begun to request proof of cell line authentication from investigators. Unlike other methods, chromosomal analysis is able to unambiguously identify cells from all common mammalian species and can also differentiate between cells from the same species. This analysis can therefore identify intra-species and inter-species cell line contaminations.
Meet the team
Left to right: Sen Pathak, Asha Multani, Jin Ma
Please contact Dr. Multani for guidelines for sample preparation, technical assistance and to discuss the services that you require.
Asha S. Multani, Ph.D.
We will take the time to understand your project and plan for the preparation of samples for analysis. We will help with interpretation of the results and upon request provide a detailed description of method as well as microphotographs (color or black and white) suitable for inclusion in reports or manuscripts to the investigators.