Publications

miR-141-Mediated Regulation of Brain Metastasis From Breast Cancer                                                                                                   
Bisrat G. Debeb, Lara Lacerda, Simone Anfossi, Parmeswaran Diagaradjane, Khoi Chu, Arvind Bambhroliya, Lei Huo, Caimiao Wei, Richard A. Larson, Adam R. Wolfe, Wei Xu, Daniel L. Smith, Li Li, Cristina Ivan, Pamela K. Allen, WenhuiWu, George A. Calin, Savitri Krishnamurthy, Xiang H. Zhang, Thomas A. Buchholz, Naoto T. Ueno, James M. Reuben, Wendy A. Woodward.  JNCI Journal of National Cancer Institute 108(8):djw026, July 2016.

Landscape of somatic mutations in 560 cancer whole-genome sequences
Nik-Zainal S, Davies H, Staaf J, Ramakrishna M, Glodzik D1, Zou X1, Martincorena I, Alexandrov LB, Martin S, Wedge DC, Van Loo P, Ju YS, Smid M, Brinkman AB, Morganella S, Aure MR, Lingjærde OC, Langerød A, Ringnér M, Ahn SM, Boyault S, Brock JE, Broeks A, Butler A, Desmedt C, Dirix L, Dronov S, Fatima A, Foekens J, Gerstung M, Hooijer GK, Jang SJ, Jones DR, Kim HY, King TA, Krishnamurthy, Lee HJ, Lee JY, Li Y1, McLaren S, Menzies A, Mustonen V, O'Meara S, Pauporté I, Pivot X, Purdie CA, Raine K, Ramakrishnan K, Rodríguez-González FG, Romieu G, Sieuwerts AM, Simpson PT, Shepherd R, Stebbings L, Stefansson OA, Teague J, Tommasi S, Treilleux I, Van den Eynden GG, Vermeulen P, Vincent-Salomon A, Yates L, Caldas C, van't Veer L, Tutt A, Knappskog S, Tan BK, Jonkers J, Borg Å, Ueno NT, Sotiriou C, Viari A, Futreal PA, Campbell PJ, Span PN, Van Laere S, Lakhani SR, Eyfjord J, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL, Richardson AL, Kong G, Thomas G, Stratton MR.   Nature 534, 47-54, June 2016.

Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism
Bisrat G. Debeb, Lara Lacerda, Richard Larson, Adam R. Wolfe1,5, Savitri Krishnamurthy, James M. Reuben, Naoto T. Ueno, Michael Gilcrease, Wendy A. Woodward. Oncotarget, Vol 7, No.19, April 2016. 

Inflammatory breast cancer: what we know and what we need to learn.                                                                       
Yamauchi H, Woodward WA, Valero V, Alvarez RH, Lucci A, Buchholz TA, Iwamoto T, Krishnamurthy S, Yang W, Reuben JM, Hortobágyi GN, Ueno NT. Oncologist. 2012;17(7):891-9. doi: 10.1634/theoncologist.2012-0039. Epub 2012 May 14.

Pre-clinical studies of Notch signaling inhibitor RO4929097 in inflammatory breast cancer cells.
Debeb BG, Cohen EN, Boley K, Freiter EM, Li L, Robertson FM, Reuben JM, Cristofanilli M, Buchholz TA, Woodward WA. Breast Cancer Res Treat. 2012 Jul;134(2):495-510. doi: 10.1007/s10549-012-2075-8. Epub 2012 May 1.

Circulating tumor cells in immunohistochemical subtypes of metastatic breast cancer: lack of prediction in HER2-positive disease treated with targeted therapy.
Giordano A, Giuliano M, De Laurentiis M, Arpino G, Jackson S, Handy BC, Ueno NT, Andreopoulou E, Alvarez RH, Valero V, De Placido S, Hortobagyi GN, Reuben JM, Cristofanilli M. Ann Oncol. 2012 May;23(5):1144-50. doi: 10.1093/annonc/mdr434. Epub 2011 Sep 28.

Selection of metastatic breast cancer cells based on adaptability of their metabolic state.
Singh B, Tai K, Madan S, Raythatha MR, Cady AM, Braunlin M, Irving LR, Bajaj A, Lucci A. PLoS One. 2012;7(5):e36510. doi: 10.1371/journal.pone.0036510. Epub 2012 May 3.

Inhibition of established micrometastases by targeted drug delivery via cell surface-associated GRP78.
Miao YR, Eckhardt BL, Cao Y, Pasqualini R, Argani P, Arap W, Ramsay RG, Anderson RL. Clin Cancer Res. 2013 Apr 15;19(8):2107-16. doi: 10.1158/1078-0432.CCR-12-2991. Epub 2013 Mar 7.

Field match verification during combination proton, photon, and electron therapy for oligometastatic inflammatory breast cancer.
Amos RA, Woodward WA. Med Dosim. 2012 Winter;37(4):442-4. doi: 10.1016/j.meddos.2012.04.002. Epub 2012 May 19.

Outcomes After Multidisciplinary Treatment of Inflammatory Breast Cancer in the Era of Neoadjuvant HER2-directed Therapy.
Tsai CJ, Li J, Gonzalez-Angulo AM, Allen PK, Woodward WA, Ueno NT, Lucci A, Krishnamurthy S, Gong Y, Yang W, Cristofanilli M, Valero V, Buchholz TA. Am J Clin Oncol. 2013 May 2. [Epub ahead of print]

Strategies to consider during the discovery and development of therapies for metastatic breast cancer.
Eckhardt, B.L., Francis, P.A., Parker, B.P., and Anderson, R.L. (2012). Nature Reviews Drug Discovery. 11(6):479-97.  

Metastasis in the Breast Mimicking Inflammatory Breast Cancer.
Alvarez RH, Gong Y, Ueno NT, Alizadeh PA, Hortobagyi GN, Valero V. J Clin Oncol. 2012.

Pretreatment staging Positron Emission Tomography/Computed Tomography in patients with inflammatory breast cancer influences radiation treatment field designs.
Walker GV, Niikura N, Yang W, Rohren E, Valero V, Woodward WA, Alvarez RH, Lucci A, Ueno NT, Buchholz TA. Int J Radiat Oncol Biol Phys. e-Pub 1/2012.

Semiquantitative analysis of maximum standardized uptake values of regional lymph nodes in inflammatory breast cancer: Is there a reliable threshold for differentiating benign from malignant?
Carkaci S, Adrada BE, Rohren E, Wei W, Quraishi MA, Mawlawi O, Buchholz TA, Yang W. Acad Radiol. e-Pub 2/2012.

18F-FDG PET/CT predicts survival in inflammatory breast cancer patients undergoing neoadjuvant chemotherapy.
Carkaci S, Sherman CT, Ozkan E, Adrada BE, Rohren E, Mawlawi O, Ueno NT, Buchholz TA, Yang W. EJNM and MI. In Press.

Statin use in primary inflammatory breast cancer: a cohort study.
Brewer TM, Masuda H, Liu DD, Shen Y, Liu P, Iwamoto T, Kai K, Barnett CM, Woodward WA, Reuben JM, Yang P, Hortobagyi GN, Ueno NT. Br J Cancer. 2013 Jul 2. doi: 10.1038/bjc.2013.342. [Epub ahead of print] 

Genomic and expression analysis of microdissected inflammatory breast cancer.
Woodward WA, Krishnamurthy S, Yamauchi H, El-Zein R, Ogura D, Kitadai E, Niwa S, Cristofanilli M, Vermeulen P, Dirix L, Viens P, van Laere S, Bertucci F, Reuben JM, Ueno NT. Breast Cancer Res Treat. 2013 Apr;138(3):761-72. doi: 10.1007/s10549-013-2501-6. Epub 2013 Apr 9. 

Uncovering the molecular secrets of Inflammatory Breast Cancer biology: An integrated analysis of three distinct Affymetrix gene expression data sets.
Van Laere SJ, Ueno NT, Finetti P, Vermeulen PB, Lucci A, Robertson FM, Marsan M, Iwamoto T, Krishnamurthy S, Masuda H, Van Dam PA, Woodward WA, Viens P, Cristofanilli M, Birnbaum D, Dirix LY, Reuben JM, Bertucci F. Clin Cancer Res. 2013 Feb 8. [Epub ahead of print] 

Role of epidermal growth factor receptor in breast cancer.
Masuda H, Zhang D, Bartholomeusz C, Doihara H, Hortobagyi GN, Ueno NT. Breast Cancer Res Treat. 2012 Nov;136(2):331-45. doi: 10.1007/s10549-012-2289-9. Epub 2012 Oct 17.