Publications
Dantzer Lab
Kappelmann N, Dantzer R, Khandaker GM. Interleukin-6 as potential mediator of long-term neuropsychiatric symptoms of COVID-19. Psychoneuroendocrinology. 2021 Sep;131:105295. doi: 10.1016/j.psyneuen.2021.105295. Epub 2021 Jun 3. PMID: 34119855; PMCID: PMC8172271.
Vichaya EG, Ford BG, Moltenkine JM, Taniguchi CM, Phillip West A, Dantzer R. Sex differences in the behavioral and immune responses of mice to tumor growth and cancer therapy. Brain Behav Immun. 2021 Aug 19;98:161-172. doi: 10.1016/j.bbi.2021.08.225. Epub ahead of print. PMID: 34418499.
Bryant JD, Kodali M, Shuai B, Menissy SS, Graves PJ, Phan TT, Dantzer R, Shetty AK, Ciaccia West L, West AP. Neuroimmune mechanisms of cognitive impairment in a mouse model of Gulf War illness. Brain Behav Immun. 2021 Jul 29:S0889-1591(21)00279-8. doi: 10.1016/j.bbi.2021.07.015. Epub ahead of print. PMID: 34333111.
Willette AA, Pappas C, Hoth N, Wang Q, Klinedinst B, Willette SA, Larsen B, Pollpeter A, Li T, Le S, Collazo-Martinez AD, Mochel JP, Allenspach K, Dantzer R; Alzheimer's Disease Neuroimaging Initiative. Inflammation, negative affect, and amyloid burden in Alzheimer's disease: Insights from the kynurenine pathway. Brain Behav Immun. 2021 Jul;95:216-225. doi: 10.1016/j.bbi.2021.03.019. Epub 2021 Mar 26. PMID: 33775832; PMCID: PMC8187283.
Dantzer R. Love and fear in the times of sickness. Compr Psychoneuroendocrinol. 2021 May;6:100032. doi: 10.1016/j.cpnec.2021.100032. Epub 2021 Feb 22. PMID: 34327337; PMCID: PMC8318348.
Grace Lab
Cata JP, Patiño M, Lacagnina MJ, Li J, Gorur A, Agudelo-Jimenez R, Wei B, Hagberg CA, Dougherty PM, Shureiqi I, Yang P, Grace PM. A rat model to investigate quality of recovery after abdominal surgery. Pain Rep. 2021 Jul-Aug;6(2):e943. doi: 10.1097/PR9.0000000000000943. eCollection 2021 Jul-Aug. PubMed PMID: 34235345; PubMed Central PMCID: PMC8253582.
Hoogendoorn A, Avery TD, Li J, Bursill C, Abell A, Grace PM. Emerging Therapeutic Applications for Fumarates. Trends Pharmacol Sci. 2021 Apr;42(4):239-254. doi: 10.1016/j.tips.2021.01.004. Epub 2021 Feb 19. Review. PubMed PMID: 33618840; PubMed Central PMCID: PMC7954891.
Lacagnina MJ, Heijnen CJ, Watkins LR, Grace PM. Autoimmune regulation of chronic pain. Pain Rep. 2021;6(1):e905. doi: 10.1097/PR9.0000000000000905. eCollection 2021. Review. PubMed PMID: 33981931; PubMed Central PMCID: PMC8108590.
Grace PM, Tawfik VL, Svensson CI, Burton MD, Loggia ML, Hutchinson MR. The Neuroimmunology of Chronic Pain: From Rodents to Humans. J Neurosci. 2021 Feb 3;41(5):855-865. doi: 10.1523/JNEUROSCI.1650-20.2020. Epub 2020 Nov 25. Review. PubMed PMID: 33239404; PubMed Central PMCID: PMC7880288.
Muscat SM, Deems NP, D'Angelo H, Kitt MM, Grace PM, Andersen ND, Silverman SN, Rice KC, Watkins LR, Maier SF, Barrientos RM. Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats. Neurobiol Aging. 2021 Feb;98:214-224. doi: 10.1016/j.neurobiolaging.2020.11.008. Epub 2020 Nov 24. PubMed PMID: 33341652; PubMed Central PMCID: PMC7870544.
- Editorials: Bhakta NR. Fire extinguishers turn down the gain on pain. Science Translational Medicine, 2016 Jun; 8: 344ec98.
- Recommended by Faculty of 1000
- Ray LB. Even more pain in opioid treatment. Science, 2016 Jul; 353: 134.
Pan Lab
Pan Y, Hysinger JD, Barron T, Schindler NF, Cobb O, Guo X, Yalçın B, Anastasaki C, Mulinyawe SB, Ponnuswami A, Scheaffer S, Ma Y, Chang KC, Xia X, Toonen JA, Lennon JJ, Gibson EM, Huguenard JR, Liau LM, Goldberg JL, Monje M, Gutmann DH. NF1 mutation drives neuronal activity-dependent initiation of optic glioma. Nature. 2021 Jun;594(7862):277-282. doi: 10.1038/s41586-021-03580-6. Epub 2021 May 26. PubMed PMID: 34040258; PubMed Central PMCID: PMC8346229.
Guo X, Pan Y, Xiong M, Sanapala S, Anastasaki C, Cobb O, Dahiya S, Gutmann DH. Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth. Nat Commun. 2020 May 1;11(1):2177. doi: 10.1038/s41467-020-15770-3. PubMed PMID: 32358581; PubMed Central PMCID: PMC7195398.
Pan Y, Monje M. Activity Shapes Neural Circuit Form and Function: A Historical Perspective. J Neurosci. 2020 Jan 29;40(5):944-954. doi: 10.1523/JNEUROSCI.0740-19.2019. Review. PubMed PMID: 31996470; PubMed Central PMCID: PMC6988998.
Guo X, Pan Y, Gutmann DH. Genetic and genomic alterations differentially dictate low-grade glioma growth through cancer stem cell-specific chemokine recruitment of T cells and microglia. Neuro Oncol. 2019 Oct 9;21(10):1250-1262. doi: 10.1093/neuonc/noz080. PubMed PMID: 31111915; PubMed Central PMCID: PMC6784288.
Pan Y, Xiong M, Chen R, Ma Y, Corman C, Maricos, Kindler U, Chen YH, Dahiya S, Gutmann DH. Athymic mice reveal a requirement for T-cell microglia interactions in establishing a microenvironment supportive of Nf1 low-grade glioma growth. Genes Dev. 2018 Apr 1;32(7-8):491-496. doi:10.1101/gad.310797.117.Epub 2018 Apr 9. PubMed PMID:29632086; PubMed Central PMCID: PMC5959233.
Shepherd Lab
English K, Shepherd A, Uzor NE, Trinh R, Kavelaars A, Heijnen CJ. Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer. Acta Neuropathol Commun. 2020 Mar 20;8(1):36. doi: 10.1186/s40478-020-00897-7. PubMed PMID: 32197663; PubMed Central PMCID: PMC7082981.
Shepherd AJ, Mohapatra DP. Attenuation of Unevoked Mechanical and Cold Pain Hypersensitivities Associated With Experimental Neuropathy in Mice by Angiotensin II Type-2 Receptor Antagonism. Anesth Analg. 2019 Jun;128(6):e84-e87. doi: 10.1213/ANE.0000000000003857. PubMed PMID: 31094778; PubMed Central PMCID: PMC6652216.
Warwick CA, Shutov LP, Shepherd AJ, Mohapatra DP, Usachev YM. Mechanisms underlying mechanical sensitization induced by complement C5a: the roles of macrophages, TRPV1, and calcitonin gene-related peptide receptors. Pain. 2019 Mar;160(3):702-711. doi: 10.1097/j.pain.0000000000001449. PubMed PMID: 30507785; PubMed Central PMCID: PMC6377341.
Shepherd AJ, Mickle AD, McIlvried LA, Gereau RW 4th, Mohapatra DP. Parathyroid hormone-related peptide activates and modulates TRPV1 channel in human DRG neurons. Eur J Pain. 2018 Oct;22(9):1685-1690. doi: 10.1002/ejp.1251. Epub 2018 Jun 11. PubMed PMID: 29797679.
Shepherd AJ, Mickle AD, Golden JP, Mack MR, Halabi CM, de Kloet AD, Samineni VK, Kim BS, Krause EG, Gereau RW 4th, Mohapatra DP. Macrophage angiotensin II type 2 receptor triggers neuropathic pain. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8057-E8066. doi: 10.1073/pnas.1721815115. Epub 2018 Aug 6. PubMed PMID: 30082378; PubMed Central PMCID: PMC6112686.