Research Resources

Services

• Automated tool for cell-based assays
  
• Drug profiling
• Toxicological studies
• Gene function

Mass Spectrometry Core Facility

• Accessible by entire MD Anderson and Texas Medical Center community
• Individual protein quantification or post-translational modification analysis
• Unbiased global quantification by stable isotope and label-free methods
• High Resolution, Accurate Mass (HRAM)
  • Orbitrap Fusion Tribrid Mass Spectrometer
• Matrix-Assisted Laser Desorption Ionization (MALDI)
  • 4700 MALDI TOF/TOF Mass Spectrometer
• Triple Quadrupoles
  • TSQ Quantiva Triple Quadrupole Mass Spectrometer

ONIX-Nikon Ti-E

• Generate proteomic imaging and measure up to 3 fluorescent reporters or markers in single cells (i.e., protein expression or interactions)
• Sort single cells based on their fluorescence for further experiments
• Track live mammalian, yeast or bacterial cells over time in up to 3 fluorescence channels plus transmitted light

Nikon TiE Epifluorescent Microscope

• Image and measure up to 3 fluorescent reporters or markers in single cells (i.e., protein expression or interactions)
• Track live mammalian, yeast or bacterial cells over time in up to 3 fluorescence channels plus transmitted light

FACSAria II System

• Measure up to 5 fluorescent reporters or markers in single cells (i.e., protein expression)
• Sort single cells based on their fluorescence for further experiments

Illumina Gene Expression Profiling

• Generate gene expression profiling data from cells and tumor tissues
• Discover potential prognostic or predictive biomarkers
• Gene expression signatures