As with most cancers, triple-negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes. A new study used single-cell sequencing technology to provide previously unknown details about how and when CNAs impact tumor formation and growth.
The study’s results, published in the online issue of Nature Genetics, challenge the prevailing belief that CNAs take place slowly...

MD Anderson again has been ranked No. 1 for cancer care by U.S. News & World Report’s annual “Best Hospitals” rankings. Since the rankings...
Chemotherapy, radiation, hormone therapy, various cancer drugs and even cancer itself can weaken patients’ bones, leading to cancer-related...
Up to 15% of colorectal cancers show a genetic mutation known as DNA mismatch repair deficiency, or dMMR. Until now, little has been known about how the mutation behaves in rectal cancer patients, what causes dMMR, and which treatments may be most effective.
A study at MD Anderson uncovered new data about dMMR’s hereditary basis in rectal cancer which may guide physicians in diagnoses, treatment and preventive measures, and in...

Reported online in the July 28 issue of Molecular Cell, a study conducted at MD Anderson has shown that a protein called ZMYND8 blocks expression...
Patients diagnosed with blood-related cancers such as leukemia, lymphoma and multiple myeloma often undergo what is called a hematopoietic...
Tobacco use has significantly declined during the past five decades since the release of the U.S. Surgeon General’s Report on Smoking &...