Why is our immune system usually not capable of eradicating cancerous tumor cells?
This is the main question that Greg Lizee, Ph.D., associate professor in the Department of Melanoma Medical Oncology, has been trying to answer. His research focuses on the interplay between cancer cells and immune cells, with the ultimate goal of developing immunotherapies that will boost a patient's own immune system to fight off cancer.
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The epidermal growth factor receptor (EGFR) often goes haywire in cancer, sending constant, urgent signals into a cell, telling it to grow...
The U.S. Centers for Disease Control and Prevention estimates obesity to be a contributing factor to millions of dollars in health care costs...
A pivotal protein leads to autoimmune inflammation of the central nervous system in a mouse model of multiple sclerosis (MS) and potentially captures a key element of the human disease.
Researchers found that Peli1 plays a central signaling role in experimental autoimmune encephalomyelitis (EAE) and reported their findings in an advance online publication at Nature Medicine.
"The major implication of discovering a signaling...